DrugMap: GAPDH (KB02)

name	peptide	bile_duct_ICC21	bile_duct_ICC137	bile_duct_ICC10	bile_duct_ICC106	bile_duct_SNU245	bile_duct_ICC11	bile_duct_ICC108	bile_duct_ICC24	bile_duct_TGBC1TKB	bile_duct_ICC20	bile_duct_ICC8	bile_duct_KMCH1	bile_duct_ICC26	bile_duct_TFK1	bile_duct_ICC3	bile_duct_ICC18	bile_duct_SNU1079	bile_duct_RBE	bile_duct_YSCCC	bile_duct_ETK1	bile_duct_ECC2	bile_duct_EGI1	bile_duct_SNU869	bile_duct_SNU1196	bile_duct_OCUG1	bile_duct_GB2	bile_duct_SNU308	bile_duct_G415	bile_duct_CCSW1	bile_duct_CCLP1	bile_duct_SG231	bile_duct_HUCCT1	bile_duct_TKKK	bile_duct_SNU478	bile_duct_HUH28	bile_duct_ICC12	bile_duct_HKGZCC	bile_duct_TGBC52TKB	bile_duct_ICC9	bile_duct_MG984	bile_duct_OZ	bile_duct_SSP25	bile_duct_ICC19	bile_duct_ICC4
CYS 152	IISNASCTTNCLAPLAK	74	71	75	79	76	58	65	71	69	69	45	62	29	58	45	60	28	31	49	36	22	52	65	34	44	35	54	42	12	42	53	49	58	52	45	63					34	32	25	10
	LTGMAFRVPTANVSVVDLTCR	26	38	38	36	-21	35	32	39	-11	32	8	-14	9	-14	-29	-17	-4	-5	-7	3	8	-11	-21	-5	-3	11	-5	17	24	18	-24	1	38	-23	39	40	19	16	21	13	-12	13	6	32

GAPDH	DNA copy number		1.11065123786894	0.842269890494365	1.02080640341214	1.17102083701151		1.15857204116424		1.14952070400527		0.978651824400841	1.179615277564		0.997144331858665	1.03092755694223		1.03025524089801	1.16873201027936	1.03607197876494		1.12838725823974	1.02107725112735	1.02729389583634	0.905318478760397	0.852307637650105	1.26536334761654	1.01826163467931	1.34535097557345	1.18834241129809	1.00592461536652	1.07932353299461	1.46929474952256	0.988803288728166	1.02439939914007	0.884218990995403	0.931230432829518	1.09652877905683	0.930975541902679	0.970581692012544			1.05206743053329		1.02111986088282
GAPDH	DNA mutation status		0	0	0	0		0		0		0	0		0	0		0	0	0		0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0		0
GAPDH	RNA expression		12.1430961771402	11.9009799856836	11.6488069497258	11.7144172568534		12.1525700569802		12.4504122559452		11.9725849647462	11.2768804585651		12.374713484505	12.067501586359		11.7003530151127	12.6139045440436	11.4712687641736		11.4600974818388	11.1198489583368	11.013880937935	11.3281700079019	12.2418640122368	12.1447219647038	11.915543308242	13.1814473516381	12.6937047392253	11.1784781225672	11.7701270146839	11.9900684989417	11.3316447626131	12.1704571475519	11.6774113405306	10.5895575227735	11.3276087789829	11.7829982089204	11.1930324684428			12.72470568811		12.8232876189175
GAPDH	CRISPR gene dependency		0.94	1.00	1.00			1.00		0.96		0.99	1.00		1.00	1.00		0.98	0.98	0.96		1.00	1.00	0.99	0.84	0.84	1.00	0.90	1.00	1.00	0.99	1.00	0.96	0.59	1.00		0.76	1.00	0.98	1.00			1.00		0.98

Cysteine	Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Pocket Volume (Å^3)	Presence at Interface	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
	GAPDH	P04406	6ynd	7.2	0.0	25.0	24.0	49.0	0.0	-2.5	-2.2	-0.6	-0.5	-0.9	37.5	-135.7	-134.8	154.6	E	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.7	0.0