DrugMap: GAPDH (KB03)

name	peptide	skin_A375	skin_RPMI7951	skin_SKMEL2	skin_HMCB	skin_SKMEL3	skin_G361	skin_UACC257	skin_SKMEL30	skin_MEWO	skin_UACC62	skin_LOXIMVI	skin_WM2664	skin_COLO792	skin_MELJUSO	skin_COLO679	skin_A2058	skin_SKMEL28	skin_IGR1	skin_HS944T	skin_IGR37	skin_RVH421	skin_IPC298	skin_WM793B	skin_MEL182	skin_MEL167	skin_IGR39	skin_CHL1	skin_COLO829	skin_A375S2	skin_A101D	skin_SKMEL24	skin_SH4	skin_HS936T	skin_WM115	skin_C32	skin_COLO853	skin_COLO800	skin_SKMEL5	skin_A431	skin_WM1552C	skin_MELHO	skin_MCC13	skin_MCC26
CYS 152	IISNASCTTNCLAPLAK	71	66	60	48	65	69	52	45	50	53	62	44	36	43	42	42	55	49	61	57	25	56	35	74	80	59	60	48	63	51	71	69	57	22	42	54	45	51	49	46	57	57	14
	LTGMAFRVPTANVSVVDLTCR	13	22	17	31	5	23	15	11	45	14	7	12	23	13	9	3	8	0	15	4	26	13	38	54	40	27	26	32	34	49	48	39	16	11	39	31	38	27	19	43	28	19	15

GAPDH	DNA copy number	1.07842357073596	0.929996386015604	0.979539181216483	0.902625538579391	0.986181320820785	1.02398105688762	1.01320589308885	0.932216700498127	0.622496959389376	1.06237833174734	1.19422464271386	0.766503340446135	1.08882187957141	1.00946534822271	1.2810927585834	0.971099401389622	0.858749718215486	1.09184167200803	0.801597670677601	1.05400907357853	1.09114483062869	1.09058247969261				1.31812953511656		1.01805508314214		1.15426139814151	1.02023849377038	0.95779207988396	0.996477311277247	1.00950158409039	0.99613668656885		0.954154893791088	1.04419845605223	1.01857658002288		0.934421713761759	0.999626548347795	1.16695295770333
GAPDH	DNA mutation status	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0				0		0		0	0	0	0	1			0	0	0		0	0	0
GAPDH	RNA expression	12.8211959911196	11.7874128739059	12.4394673081047	11.927407612949	11.8969756449528	12.472005370899	12.5862064765764	12.8563282562632	11.9200178254083	13.0305636888211	12.8162236890596	12.174894482011	11.9853082972559	12.8581364495796	13.6519486107234	12.6921141761429	12.354332039721	12.9912560992833	12.1619506477906	12.8344908019717	12.0454525270988	12.7564520777868				12.9961556794928		12.3932295531137		12.676221561569	13.3721848964864	12.9853082972559	12.8988847595935	12.9832608476825	13.4070021479242		12.6428414380336	12.2110973933293	11.6847486204216		12.8014052398816	11.770787759526	12.5599506127131
GAPDH	CRISPR gene dependency	1.00	1.00	1.00				0.92	0.98		0.99		0.99	0.96	1.00	1.00	1.00		1.00	1.00		0.84	1.00				1.00					0.97	0.98	0.99	0.63	0.99		1.00		0.99		0.99	0.96	0.98

Cysteine	Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Pocket Volume (Å^3)	Presence at Interface	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
	GAPDH	P04406	6ynd	7.2	0.0	25.0	24.0	49.0	0.0	-2.5	-2.2	-0.6	-0.5	-0.9	37.5	-135.7	-134.8	154.6	E	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.7	0.0