DrugMap cysteine engagement data for:
Probe: KB05 KB02 | Download Table Download Statistics |
name | peptide | skin_A375 | skin_RPMI7951 | skin_SKMEL2 | skin_HMCB | skin_SKMEL3 | skin_G361 | skin_UACC257 | skin_SKMEL30 | skin_MEWO | skin_UACC62 | skin_LOXIMVI | skin_WM2664 | ovary_TOV21G | ovary_OVTOKO | ovary_EFO21 | ovary_OVK18 | ovary_OV90 | ovary_PEO1 | ovary_OAW28 | ovary_OVCAR4 | ovary_SKOV3 | ovary_OVISE | ovary_NIHOVCAR3 | ovary_EFO27 | bile_duct_ICC21 | bile_duct_ICC137 | bile_duct_ICC10 | bile_duct_ICC106 | bile_duct_SNU245 | bile_duct_ICC11 | bile_duct_ICC108 | bile_duct_ICC24 | bile_duct_TGBC1TKB | bile_duct_ICC20 | bile_duct_ICC8 | bile_duct_KMCH1 | ovary_OVKATE | ovary_OVCAR5 | ovary_A2780 | ovary_CAOV3 | ovary_MCAS | ovary_OVCA429 | ovary_OAW42 | soft_tissue_RKN | bile_duct_ICC26 | bile_duct_TFK1 | bile_duct_ICC3 | bile_duct_ICC18 | lung_MGH0061 | lung_NCIH3122 | lung_MGH0651 | lung_MGH0261 | lung_MGH0732 | lung_MGH0653 | lung_MGH9153 | lung_MGH0752 | lung_MGH97967 | lung_MGH9521R | lung_MGH92431 | lung_MGH91621 | skin_COLO792 | skin_MELJUSO | skin_COLO679 | skin_A2058 | skin_SKMEL28 | skin_IGR1 | skin_HS944T | skin_IGR37 | skin_RVH421 | skin_IPC298 | skin_WM793B | breast_AU565 | breast_CAL148 | breast_ZR751 | breast_MCF7 | breast_HDQP1 | breast_HCC1419 | breast_CAL51 | breast_MDAMB231 | breast_BRX142JUNE | breast_BRX330FEB | breast_BRX50 | breast_BRX82 | breast_BRX394JUNE | breast_BRX29 | breast_BRX330JAN | breast_BRX401 | breast_BRX68 | breast_BRX390 | breast_BRX250MAY | breast_BRX211MAY | skin_MEL182 | skin_MEL167 | skin_IGR39 | fibroblast_HS839T | blood_CMK | blood_THP1 | blood_U937 | blood_MONOMAC1 | blood_KASUMI1 | blood_MOLM13 | blood_P31FUJ | blood_OCIAML5 | bile_duct_SNU1079 | bile_duct_RBE | bile_duct_YSCCC | bile_duct_ETK1 | bile_duct_ECC2 | bile_duct_EGI1 | bile_duct_SNU869 | bile_duct_SNU1196 | bile_duct_OCUG1 | bile_duct_GB2 | bile_duct_SNU308 | bile_duct_G415 | lymphocyte_HT | lymphocyte_A3KAW | lymphocyte_RL | lymphocyte_KARPAS422 | lung_MGH8022 | lung_MGH8021 | lung_MGH8091 | lung_MGH9201 | lung_MGH1701 | lung_MGH100151 | lung_MGH1542 | lung_MGH100164 | bile_duct_CCSW1 | bile_duct_CCLP1 | bile_duct_SG231 | bile_duct_HUCCT1 | skin_CHL1 | skin_COLO829 | skin_A375S2 | skin_A101D | skin_SKMEL24 | skin_SH4 | skin_HS936T | lung_MGH90921 | plasma_cell_KMS12BM | plasma_cell_KMS11 | plasma_cell_KMS27 | plasma_cell_RPMI8226 | ovary_TYKNU | ovary_FUOV1 | lung_ABC1 | lung_A549 | lung_HCC15 | lung_CALU6 | pancreas_CFPAC1 | pancreas_BXPC3 | pancreas_KP4 | pancreas_HUPT4 | breast_HCC1937 | breast_HCC1806 | breast_CAMA1 | breast_BT549 | breast_MDAMB436 | lung_MGH1543 | lung_MGH1541 | lung_MGH8222 | lung_MGH1904 | bile_duct_TKKK | bile_duct_SNU478 | bile_duct_HUH28 | bile_duct_ICC12 | lung_NCIH1703 | lung_LU65 | lung_NCIH1155 | liver_HLF | liver_HUH7 | liver_JHH6 | liver_JHH1 | bile_duct_HKGZCC | bile_duct_TGBC52TKB | bile_duct_ICC9 | bile_duct_MG984 | bile_duct_OZ | bile_duct_SSP25 | bile_duct_ICC19 | bile_duct_ICC4 | brain_MGG75 | brain_MGG23 | brain_MGG123 | kidney_KMRC1 | kidney_CAKI1 | kidney_KMRC20 | kidney_786O | colorectal_SW403 | colorectal_RKO | colorectal_MDST8 | colorectal_SW948 | uterus_HEC1 | uterus_AN3CA | uterus_MFE296 | uterus_RL952 | lung_NCIH2172 | lung_HCC44 | lung_CORL23 | lung_NCIH1299 | colorectal_HCT15 | colorectal_LS513 | colorectal_HT115 | colorectal_HT29 | upper_aerodigestive_DETROIT562 | upper_aerodigestive_BICR22 | upper_aerodigestive_CAL27 | upper_aerodigestive_HSC3 | ovary_OV56 | ovary_IGROV1 | pancreas_SW1990 | pancreas_DANG | pancreas_HUPT3 | pancreas_PATU8988T | prostate_LNCAPCLONEFGC | prostate_DU145 | prostate_VCAP | prostate_PC3 | lung_NCIH1666 | lung_NCIH23 | lung_SW1573 | lung_NCIH1944 | lung_PC14 | lung_HCC827 | lung_LUDLU1 | lung_NCIH1975 | esophagus_KYSE150 | esophagus_TE11 | esophagus_KYSE30 | esophagus_KYSE510 | bone_CAL72 | bone_U2OS | bone_SAOS2 | bone_SJSA1 | uterus_MFE280 | cervix_SISO | uterus_ISHIKAWAHERAKLIO02ER | uterus_SNGM | lung_NCIH2170 | lung_NCIH2122 | lung_NCIH1792 | blood_MOLM16 | blood_MONOMAC6 | blood_JURLMK1 | blood_NOMO1 | blood_KASUMI2 | blood_697 | blood_REH | blood_JM1 | skin_WM115 | skin_C32 | skin_COLO853 | urinary_tract_KU1919 | urinary_tract_HT1376 | urinary_tract_UMUC3 | urinary_tract_J82 | urinary_tract_RT112 | urinary_tract_TCCSUP | urinary_tract_HT1197 | urinary_tract_T24 | breast_MDAMB453 | breast_DU4475 | breast_CAL120 | lung_NCIH1048 | lung_SW1271 | lung_NCIH446 | lung_NCIH2286 | thyroid_8505C | thyroid_8305C | thyroid_FTC133 | thyroid_CAL62 | breast_MDAMB157 | breast_HCC1143 | breast_MDAMB468 | central_nervous_system_GB1 | central_nervous_system_KNS81FD | central_nervous_system_LN229 | central_nervous_system_T98G | liver_SNU449 | liver_SNU423 | liver_HUH1 | liver_JHH4 | liver_SKHEP1 | liver_JHH7 | liver_HEP3B217 | liver_HEPG2 | skin_COLO800 | skin_SKMEL5 | esophagus_KYSE180 | esophagus_KYSE410 | esophagus_TE4 | esophagus_TE1 | ovary_KURAMOCHI | ovary_OVCAR8 | pancreas_PANC0403 | pancreas_MIAPACA2 | pancreas_SUIT2 | blood_MV411 | blood_KO52 | blood_TF1 | blood_OCIAML2 | cervix_HT3 | cervix_CASKI | cervix_C4II | cervix_DOTC24510 | lymphocyte_SUDHL4 | blood_NALM6 | lymphocyte_JEKO1 | blood_JVM3 | skin_A431 | esophagus_OE33 | esophagus_TE10 | lymphocyte_OCILY3 | blood_MEC1 | blood_HG3 | lymphocyte_SUDHL6 | breast_HS578T | breast_KPL1 | breast_HCC1954 | breast_HCC1395 | colorectal_COLO678 | colorectal_LS123 | colorectal_SW1116 | colorectal_CCK81 | bone_SKNMC | bone_A673 | bone_SKES1 | bone_TC71 | central_nervous_system_DAOY | central_nervous_system_D283MED | central_nervous_system_PFSK1 | central_nervous_system_ONS76 | uterus_SKN | uterus_MFE319 | kidney_OSRC2 | kidney_769P | kidney_RCC10RGB | lung_NCIH1793 | lung_NCIH1650 | lung_CALU1 | lung_NCIH358 | skin_WM1552C | skin_MELHO | lung_NCIH2052 | lung_MSTO211H | lung_CORL88 | lung_SBC5 | gastric_KATOIII | gastric_MKN45 | gastric_OCUM1 | gastric_SNU1 | peripheral_nervous_system_SKNAS | peripheral_nervous_system_KPNYN | peripheral_nervous_system_NB1 | peripheral_nervous_system_KELLY | kidney_G401 | soft_tissue_A204 | soft_tissue_KYM1 | kidney_G402 | lung_NCIH196 | lung_NCIH146 | lung_SHP77 | lung_NCIH82 | gastric_HGC27 | gastric_AGS | gastric_NCIN87 | gastric_IM95 | upper_aerodigestive_FADU | upper_aerodigestive_CAL33 | upper_aerodigestive_SCC25 | upper_aerodigestive_HSC4 | cervix_SW756 | bone_CAL78 | lymphocyte_KARPAS299 | gastric_MKN1 | plasma_cell_OPM2 | plasma_cell_SKMM2 | soft_tissue_HT1080 | central_nervous_system_LN18 | breast_HCC1187 | breast_HCC70 | blood_HEL9217 | blood_HEL | blood_EOL1 | gastric_SNU5 | gastric_NUGC3 | soft_tissue_RD | soft_tissue_RH30 | soft_tissue_RH41 | lymphocyte_REC1 | esophagus_TE8 | pancreas_PANC1 | kidney_KMRC3 | lung_NCIH2291 | lymphocyte_L428 | unknown_HDMYZ | skin_MCC13 | skin_MCC26 | prostate_22RV1 | kidney_A498 | kidney_VMRCRCW | colorectal_SW837 | colorectal_LS180 | colorectal_SW620 | colorectal_COLO320 | central_nervous_system_SF295 | central_nervous_system_A172 | central_nervous_system_GAMG | central_nervous_system_KNS42 | blood_JURKAT | blood_PF382 | lymphocyte_DEL | blood_SUPT1 | central_nervous_system_SW1783 | central_nervous_system_42MGBA | central_nervous_system_U87MG | central_nervous_system_U118MG |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
VLISDSLDPCCR | 37 | 33 | 45 | 32 | 21 | 41 | 41 | 36 | 72 | -10 | 22 | 26 | 20 | 13 | 7 | -4 | 2 | 14 | 25 | 29 | 83 | 57 | 29 | 40 | 42 | 20 | -4 | 44 | 36 | 29 | 35 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
EELIAELQDCEGLIVR | -2 | 1 | 42 | 11 | 33 | -42 | 16 | -5 | 28 | 11 | 35 | 9 | -7 | 22 | 26 | -9 | -20 | 0 | -16 | -17 | 39 | 23 | 60 | 74 | 37 | 16 | 34 | 18 | 28 | 49 | 28 | -21 | 11 | 49 | 9 | 33 | 8 | 8 | 34 | 4 | 35 | -21 | 43 | 6 | 12 | 9 | 13 | -3 | -9 | -23 | -14 | -4 | -15 | 7 | 6 | -13 | 21 | -23 | -37 | 15 | -35 | -25 | -26 | 18 | 12 | -8 | -38 | 4 | -5 | 8 | -46 | 12 | -30 | -38 | 31 | -34 | -17 | -36 | -41 | 33 | -14 | -19 | 4 | 21 | -32 | 51 | -6 | -17 | 21 | 15 | 17 | 6 | 8 | 27 | -12 | 9 | -15 | 36 | 38 | 28 | 17 | 39 | 60 | 8 | 35 | 20 | 41 | 70 | 53 | -42 | -6 | 12 | -32 | -12 | -5 | 13 | 0 | -37 | 0 | 41 | 46 | -9 | 23 | 39 | 53 | 42 | -37 | 35 | -17 | 45 | 26 | 43 | -15 | 37 | 51 | 25 | 20 | 11 | 17 | 41 | 51 | 27 | 7 | 39 | 28 | 69 | -1 | 9 | -31 | 39 | 80 | 4 | 40 | 6 | 0 | 12 | 45 | -13 | -12 | 18 | 50 | -33 | -35 | -36 | 40 | -18 | -18 | 67 | 24 | 53 | -23 | 39 | 21 | 8 | 8 | 4 | 1 | 1 | -7 | -26 | -9 | 50 | 37 | 1 | 38 | 18 | -10 | -2 | 41 | 7 | -17 | -9 | -3 | 16 | 37 | 8 | 20 | 65 | 48 | 8 | 35 | -20 | 21 | 8 | 6 | 11 | 7 | 16 | 23 | 1 | 27 | 3 | 19 | 1 | 8 | -5 | 16 | 25 | 4 | -11 | 43 | 30 | 16 | 17 | -25 | 13 | 0 | 53 | 47 | 38 | 41 | 18 | 36 | 25 | 13 | 26 | 47 | -10 | -4 | 35 | 17 | 31 | 16 | 27 | 9 | 36 | 26 | 55 | 39 | 44 | -7 | -6 | 1 | 2 | 0 | 24 | 28 | 32 | 56 | 46 | 54 | -18 | 14 | 16 | -8 | 32 | 4 | -39 | 7 | 7 | 19 | 40 | 55 | -2 | 24 | 15 | -7 | -5 | -2 | -15 | -21 | 20 | -8 | -26 | -4 | 9 | 11 | -23 | 18 | 40 | -4 | 9 | -3 | -1 | 7 | -11 | 31 | 2 | -5 | 47 | 20 | 29 | 25 | -7 | 27 | 13 | 6 | 15 | 5 | -24 | -7 | 27 | 15 | 18 | 10 | 10 | -4 | -16 | 4 | 17 | 8 | -25 | 56 | -35 | 19 | 30 | -6 | -20 | -21 | -24 | 2 | -28 | -15 | 1 | -13 | -13 | -23 | -1 | -35 | 18 | 10 | -12 | -20 | -13 | -6 | 38 | -19 | 11 | -27 | -21 | -3 | 8 | 10 | 12 | 20 | 64 | 30 | 53 | -9 | -2 | -27 | -36 | 4 | 58 | -14 | 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
* | VVNCAHGGIVDEGALLR | 20 | 3 | 35 | 55 | 47 | 78 | 38 | 38 | 32 | 21 | 56 | 57 | 65 | 19 | 35 | 48 | 79 | 39 | 45 | 39 | 45 | 52 | 45 | 39 | 19 | 39 | 51 | 44 | 44 | 60 | 42 | 46 | 41 | 36 | 35 | 53 | 31 | 24 | 33 | 40 | 46 | 29 | 12 | 32 | 27 | 26 | -8 | 45 | 36 | 38 | 40 | 45 | 35 | 31 | 41 | 29 | 38 | 25 | 54 | 35 | 45 | 40 | -13 | -3 | 22 | 18 | -1 | 16 | 73 | 43 | 12 | 34 | 41 | 48 | 64 | 22 | 31 | 96 | 60 | 31 | 41 | 22 | 28 | 40 | 17 | 31 | 28 | 44 | 75 | 32 | 27 | 7 | 35 | 62 | 37 | 39 | 31 | -4 | 15 | 32 | 39 | 40 | 40 | 30 | 31 | 62 | 29 | 35 | 33 | 11 | 18 | 27 | 38 | 34 | 30 | 28 | 37 | 25 | 26 | 50 | 35 | 39 | 45 | 44 | 27 | 43 | -10 | 3 | 57 | 12 | 54 | 42 | -14 | 17 | -8 | 25 | 11 | 37 | 18 | 16 | 30 | 24 | 16 | 27 | 37 | 12 | 27 | 29 | 29 | 19 | -5 | 20 | 14 | 31 | 45 | 48 | 47 | 22 | 21 | 34 | 18 | 32 | 66 | 18 | 38 | 28 | 24 | 12 | 41 | 22 | 30 | 41 | 41 | 29 | 37 | 28 | 43 | 37 | 22 | 24 | 34 | 23 | 33 | 10 | 46 | 40 | 31 | 49 | 59 | 25 | 17 | 1 | 19 | 34 | 32 | 25 | 53 | 37 | 27 | 46 | 32 | 30 | 15 | 19 | 17 | 13 | 20 | 11 | 19 | 27 | 31 | 23 | 1 | 3 | 10 | -3 | 9 | 12 | 26 | 38 | 29 | 29 | 20 | 32 | 39 | 35 | 30 | 9 | 27 | 9 | 12 | 21 | 21 | 8 | 29 | 11 | -8 | 24 | 31 | 27 | 27 | 41 | 1 | 26 | 15 | 17 | -2 | 23 | 27 | 19 | 26 | 27 | 29 | 23 | 29 | 28 | 4 | 52 | 27 | 60 | 27 | 48 | 45 | 7 | 24 | 16 | 30 | 46 | 18 | 60 | 30 | 22 | 37 | 14 | 30 | 34 | 45 | 27 | -12 | 25 | 19 | -6 | 28 | 31 | 43 | 28 | 17 | 34 | 15 | 32 | 6 | 44 | 22 | 22 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ALQSGQCAGAALDVFTEEPPR | 40 | 34 | 33 | 35 | 38 | 7 | -20 | 20 | 39 | 40 | 37 | 35 | 24 | 15 | 32 | 10 | 27 | 4 | 11 | -1 | 35 | 15 | 36 | 7 | 50 | 40 | 22 | 30 | 29 | 26 | 52 | 14 | 22 | 42 | 12 | 49 | 44 | 28 | 35 | 33 | 34 | 30 | 13 | 8 | 16 | 29 | 8 | 32 | 42 | 17 | 15 | 29 | 25 | 18 | 22 | 18 | 31 | 24 | 8 | 23 | 32 | 27 | 20 | 20 | 1 | 19 | 19 | 18 | 12 | 42 | 24 | 26 | 20 | 37 | 15 | 37 | 19 | 20 | 26 | 35 | 30 | 36 | 27 | 31 | 34 | 38 | 24 | 34 | 30 | 24 | 27 | 6 | 21 | 1 | 5 | 20 | 27 | 8 | 23 | 31 | 6 | 47 | 11 | 53 | 20 | 61 | 15 | 40 | 35 | 35 | 43 | 31 | -4 | 27 | 13 | 23 | 11 | 1 | 37 | 56 | 37 | 23 | 32 | 49 | 56 | 37 | 15 | 39 | 9 | 38 | 21 | 33 | 27 | 36 | 18 | 18 | 42 | 18 | 33 | 36 | 22 | 10 | 14 | 19 | 32 | 31 | 10 | 8 | 6 | 9 | 24 | -7 | -4 | 26 | 23 | 43 | 0 | 27 | 15 | 17 | -20 | 7 | 5 | 3 | 18 | 10 | 7 | 3 | 11 | 10 | 28 | 20 | 5 | 25 | 28 | 25 | 3 | 32 | 20 | 26 | 1 | 33 | 22 | 11 | 14 | 14 | 10 | 38 | 17 | 22 | 55 | 25 | 42 | 36 | -11 | 19 | -3 | 9 | 11 | 28 | 22 | 20 | 35 | 24 | 20 | 24 | 29 | 13 | 20 | 46 | 33 | 25 | -9 | 22 | 15 | 29 | 40 | 34 | 41 | 23 | 11 | 33 | 30 | 48 | 33 | 40 | 36 | 16 | 30 | 22 | 26 | 29 | 25 | 5 | 22 | 32 | 19 | 26 | 25 | 17 | 22 | 27 | 26 | 30 | 32 | 11 | 17 | 12 | 19 | 18 | 9 | 38 | 40 | 30 | 40 | 31 | 23 | 47 | 37 | 41 | 19 | 33 | 18 | -4 | 31 | 24 | 5 | 15 | 16 | 42 | 21 | 41 | 36 | 10 | 42 | 29 | 24 | 8 | 9 | -3 | 11 | 6 | 15 | 22 | 13 | 24 | 30 | 3 | 25 | 37 | 11 | 20 | 4 | 31 | -5 | 18 | 11 | 25 | 16 | 41 | 25 | 37 | 31 | 9 | 6 | 13 | 13 | 19 | 20 | 0 | 20 | 23 | 0 | 17 | 16 | 21 | 4 | 25 | 7 | 30 | 18 | 4 | 21 | -3 | 27 | 19 | 25 | -6 | 6 | 5 | 8 | -1 | 6 | 24 | 1 | 29 | 7 | 24 | 8 | 46 | 34 | 6 | 3 | 1 | 8 | 8 | 20 | 21 | 16 | 12 | 14 | 27 | 18 | 21 | 14 | 26 | 3 | 22 | 16 | 37 | 25 | 11 | 9 | 3 | 15 | 12 | 37 | 28 | 21 | |||||||||||||||||||||||||||||||||||||||||||||||||
ALVDHENVISCPHLGASTK | 42 | 40 | 48 | 48 | -2 | 2 | 21 | 50 | 42 | 53 | 29 | 25 | 54 | 58 | 11 | 26 | 40 | 53 | 28 | 63 | 47 | 57 | 46 | 65 | 50 | 16 | 24 | -5 | 15 | 20 | 30 | 29 | 33 | 20 | 51 | 21 | 44 | 50 | 30 | 50 | 41 | 36 | 61 | 12 | 0 | 32 | 39 | 34 | 11 | 59 | 29 | 70 | 45 | 8 | 16 | 27 | 45 | 31 | 25 | 41 | 26 | 23 | 48 | 28 | 43 | 42 | 29 | 37 | 45 | 53 | 43 | 38 | 16 | 33 | 54 | 28 | 36 | 55 | 41 | 62 | 45 | 71 | 37 | 63 | 5 | 44 | 20 | 45 | 39 | 42 | 53 | 49 | 40 | 53 | 28 | 32 | 58 | 48 | 33 | 46 | 41 | 54 | 42 | 27 | 53 | 40 | 36 | 38 | 36 | 48 | 41 | 37 | 79 | 64 | 37 | 37 | 43 | 57 | 43 | 41 | 44 | 25 | 48 | 35 | 50 | 55 | 41 | 25 | 33 | 44 | 41 | 48 | 47 | 22 | 26 | 56 | 51 | 24 | 36 | 67 | 75 | 44 | 27 | 63 | 37 | 64 | 56 | 71 | 42 | 62 | 77 | 47 | 48 | 45 | 46 | 65 | 55 | 45 | 31 | 69 | 54 | 64 | 59 | 15 | 33 | 66 | 61 | 44 | 57 | 50 | 62 | -6 | 53 | 41 | 52 | 50 | 44 | 7 | 44 | 1 | 31 | 29 | 32 | 32 | 0 | 14 | 17 | -10 | 49 | 42 | -15 | -16 | 2 | 55 | 17 | 16 | -13 | 20 | 25 | 16 | 52 | 19 | 35 | 34 | 44 | 30 | 42 | 39 | 17 | 54 | 42 | 56 | 18 | 55 | 44 | 2 | 15 | 64 | 35 | 19 | 24 | 11 | 29 | 52 | 37 | 39 | 59 | 42 | 47 | 57 | 12 | 49 | 17 | 39 | 41 | 35 | 46 | 19 | 41 | 28 | 40 | 36 | 54 | 24 | 49 | 52 | 49 | 53 | 27 | 45 | 30 | 46 | 51 | 59 | 25 | 57 | 18 | 68 | 52 | 61 | 40 | 45 | 43 | 47 | 64 | 52 | 55 | 29 | 24 | 36 | 69 | 48 | 52 | 48 | 47 | 48 | 51 | 55 | 60 | 48 | 59 | 40 | 22 | 38 | 34 | 11 | 62 | 55 | 58 | 56 | 59 | 58 | 61 | 59 | 46 | 47 | 48 | 41 | 14 | 55 | 42 | 22 | 27 | 41 | 50 | 52 | 46 | 50 | 28 | 44 | 19 | 41 | 41 | 37 | 27 | 32 | 40 | 24 | 33 | 21 | 42 | 33 | 15 | 44 | 59 | 26 | 42 | 38 | 43 | 37 | 29 | 52 | 52 | 30 | 48 | 45 | 54 | 45 | 37 | 49 | 45 | 34 | 27 | 40 | 16 | 36 | 42 | 28 | 48 | 26 | 56 | 40 | 52 | 32 | 40 | 41 | 6 | 32 | 10 | 0 | 37 | 25 | 21 | -1 | 34 | 22 | 32 | 29 | 33 | 20 | 34 | 41 | 15 | 29 | 16 | 39 | 17 | 57 | 40 | 38 | 32 | 32 | 30 | 16 | 26 | 55 | 51 | 54 | 30 | 36 | 36 | 21 | 46 | 26 | 37 | 37 | 33 | 24 | 47 | 45 | 52 | 52 | 33 | 32 | 11 | 25 | 44 | 54 | 56 | 54 | ||||||||
CGEEIAVQFVDMVK | 18 | 4 | 39 | 20 | 6 | 17 | 38 | 13 | 28 | 19 | 2 | 16 | 13 | 18 | 31 | 34 | 34 | 32 | 39 | 47 | 28 | 50 | 20 | 56 | 24 | 9 | 35 | 0 | 25 | 14 | 15 | 45 | 35 | 21 | 17 | 21 | 18 | 28 | -1 | 39 | 20 | 17 | 27 | 14 | 18 | 6 | 21 | 31 | 22 | 11 | 21 | 11 | 22 | 3 | 7 | 2 | 2 | 53 | -1 | 0 | 7 | 11 | 35 | 11 | 15 | 33 | 55 | 40 | 17 | 26 | 19 | 16 | 54 | 38 | 12 | 37 | 38 | 45 | 58 | 36 | -8 | 2 | 19 | 23 | 11 | 13 | 15 | 28 | 19 | 22 | 53 | 31 | 30 | 1 | 52 | 7 | 40 | 33 | 70 | 31 | 32 | 33 | 42 | 26 | 15 | 31 | 20 | 3 | 49 | 69 | 33 | 49 | 15 | 28 | 20 | 22 | 13 | 20 | 17 | 19 | 20 | -5 | 3 | 31 | 22 | 29 | 37 | 41 | 40 | 35 | 37 | 26 | 46 | 64 | 44 | 40 | 44 | 31 | 21 | 38 | 49 | 53 | 32 | 39 | 22 | 28 | 40 | 30 | 27 | 45 | 43 | 45 | 50 | 7 | 34 | 24 | 31 | 33 | 42 | 34 | 17 | 39 | 32 | 28 | 25 | 23 | 21 | 6 | 11 | 27 | 23 | 16 | 28 | 6 | 63 | 39 | 57 | 48 | 51 | 60 | 32 | 30 | 29 | 30 | 38 | 39 | 7 | 20 | 44 | 33 | 24 | 41 | 48 | 37 | 34 | 47 | 48 | 52 | 38 | 28 | 32 | 43 | 33 | 29 | 40 | 38 | 25 | 58 | 39 | 49 | 19 | 30 | 34 | 29 | 34 | 23 | 14 | 37 | 26 | 38 | 40 | 33 | 24 | 39 | 22 | 29 | 20 | 43 | 15 | 28 | 40 | 35 | 22 | 22 | 30 | 23 | 3 | 42 | 36 | 12 | 26 | 20 | 22 | 27 | 21 | 37 | 32 | 43 | 38 | 22 | 34 | 27 | 14 | 34 | 25 | 8 | 20 | 9 | 7 | 33 | 13 | 28 | 14 | 38 | 22 | 16 | 30 | 9 | 28 | 14 | 39 | 42 | 26 | 19 | 35 | 13 | 13 | 27 | 48 | 0 | 23 | 13 | 27 | 12 | 29 | 15 | 27 | 17 | 16 | 32 | 20 | 28 | 14 | 14 | 29 | 31 | 20 | 12 | 25 | 12 | 27 | 16 | 6 | 7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CYS 369 | NAGNCLSPAVIVGLLK | 82 | 83 | 86 | 90 | 35 | 82 | 79 | 85 | 90 | 90 | 81 | 70 | 84 | 70 | 79 | 87 | 93 | 87 | 83 | 87 | 85 | 79 | 84 | 94 | 95 | 88 | 86 | 83 | 75 | 64 | 63 | 91 | 4 | 77 | 26 | 26 | 85 | 82 | 92 | 88 | 87 | 53 | 72 | 93 | 45 | 80 | 85 | 86 | 74 | 92 | 93 | 72 | 76 | 86 | 91 | 86 | 92 | 91 | 14 | 19 | 81 | 90 | 94 | 94 | 88 | 93 | 69 | 91 | 42 | 96 | 97 | 84 | 87 | 91 | 92 | 89 | 57 | 76 | 91 | 82 | 94 | 88 | 94 | 84 | 74 | 87 | 43 | 87 | 97 | 92 | 96 | 84 | 92 | 93 | 77 | 70 | 39 | 72 | 62 | 86 | 93 | 29 | 81 | 64 | 76 | 56 | 88 | 78 | 87 | 73 | 71 | 87 | 92 | 73 | 88 | 92 | 58 | 45 | 74 | 90 | 90 | 93 | 91 | 83 | 85 | 75 | 81 | 89 | 92 | 94 | 96 | 94 | 86 | 85 | 94 | 81 | 95 | 86 | 84 | 94 | 97 | 82 | 85 | 97 | 94 | 95 | 92 | 92 | 95 | 93 | 86 | 77 | 60 | 79 | 83 | 89 | 87 | 94 | 94 | 74 | 90 | 94 | 89 | 93 | 89 | 97 | 85 | 55 | 94 | 85 | 63 | 82 | 7 | 55 | 47 | 85 | 83 | 74 | 90 | 84 | 88 | 39 | 85 | 89 | 74 | 89 | 92 | 69 | 93 | 78 | 79 | 87 | 90 | 71 | 78 | 67 | 36 | 72 | 84 | 58 | 82 | 80 | 82 | 86 | 75 | 85 | 91 | 93 | 88 | 88 | 85 | 72 | 57 | 19 | 83 | 75 | 75 | 87 | 86 | 81 | 81 | 81 | 89 | 88 | 83 | 92 | 67 | 83 | 91 | 81 | 85 | 74 | 92 | 87 | 87 | 88 | 86 | 86 | 93 | 78 | 75 | 89 | 83 | 90 | 93 | 76 | 91 | 84 | 81 | 79 | 69 | 72 | 75 | 77 | 88 | 63 | 77 | 92 | 64 | 79 | 63 | 87 | 89 | 76 | 85 | 65 | 58 | 92 | 92 | 83 | 89 | 87 | 76 | 68 | 88 | 77 | 70 | 75 | 68 | 79 | 91 | 80 | 86 | 79 | 89 | 84 | 87 | 86 | 72 | 69 | 74 | 71 | 90 | 80 | 90 | 80 | 82 | 89 | 85 | 45 | 91 | 92 | 74 | 69 | 81 | 80 | 56 | 87 | 57 | 34 | 80 | 75 | 77 | 88 | 86 | 72 | 76 | 90 | 85 | 87 | 90 | 91 | 64 | 82 | 86 | 79 | 87 | 82 | 88 | 92 | 89 | 73 | 81 | 79 | 85 | 23 | 80 | 92 | 87 | 85 | 92 | 39 | 79 | 92 | 88 | 78 | 93 | 88 | 94 | 84 | 90 | 83 | 27 | 89 | 93 | 94 | 91 | 91 | 86 | 65 | 84 | 86 | 85 | 85 | 8 | 85 | 86 | 85 | 86 | 88 | 85 | 73 | 84 | 70 | 83 | 91 | 90 | 91 | 72 | 86 | 84 | 56 | 65 | 52 | 78 | 77 | 68 | 83 | 54 | 80 | 86 | 89 | 92 | 96 | 93 | 88 | 75 | 84 | 87 | 89 | 87 | 88 | 83 | 75 | 87 | 85 | |||||||||||
PHGDH | DNA copy number | 1.08577225133498 | 1.09292015984736 | 1.62045527571331 | 1.00205149574989 | 1.08010331123351 | 1.01771798009804 | 1.14883101272233 | 1.25458053307856 | 1.00558426590135 | 1.07995891833598 | 0.959886652963831 | 1.40148869008426 | 0.994039364576736 | 0.918070186230214 | 1.31181097348351 | 1.00533482728845 | 1.02075974549882 | 1.09301790145481 | 1.36402334135254 | 1.04527484794726 | 1.05158654013213 | 1.23448588773225 | 1.01441126669469 | 1.13779405403235 | 0.740448303816749 | 0.903875600319968 | 1.15488545568103 | 1.47104002110976 | 1.39466558133709 | 0.751813656090129 | 1.17072345873768 | 1.01664795970722 | 0.889527966023906 | 1.02852809908145 | 1.2513980800014 | 1.09856098692039 | 1.09491652138609 | 1.31230908382645 | 1.12457018233871 | 0.971782466339412 | 0.876482348997776 | 0.951018312818169 | 0.821767250070994 | 0.973435659515332 | 1.74131440304789 | 0.975598418429519 | 1.1286151541643 | 1.02481785873168 | 0.93878258553207 | 1.86449627859963 | 1.20292660626317 | 0.985861465655612 | 1.26367744230954 | 1.02997447700613 | 1.02105290324452 | 1.13197796861611 | 1.02551572172341 | 1.1983727842501 | 0.930405070634609 | 1.00475480967831 | 1.05030920544215 | 1.32659962401581 | 1.14334566981952 | 1.00077420762391 | 1.00452407122957 | 0.974120366033681 | 0.997344947607448 | 0.993548489900791 | 1.25483730055181 | 1.07275581528921 | 1.00220568352076 | 0.994884102952812 | 1.01510273258332 | 1.03613499870674 | 1.05470695916055 | 1.13589441456422 | 0.984943398031732 | 1.19658614784147 | 1.09675132047943 | 1.01268931866103 | 1.00685320037247 | 1.0150613061995 | 0.98191775815051 | 1.41459341894234 | 1.01287494168128 | 0.825965272431997 | 0.952052240385974 | 0.747865745378424 | 1.15920479649057 | 1.02158255977089 | 1.26349305871352 | 0.978845408465616 | 0.889822535238806 | 0.795782349883345 | 0.984650533756616 | 1.32188939480072 | 1.1653430079759 | 1.05375301888561 | 0.963975319362439 | 0.812766033180691 | 1.08070262765575 | 0.921536526646135 | 1.08847380219724 | 1.1622684995519 | 0.961846733520358 | 0.945076008767481 | 1.36493894531944 | 0.942182108574755 | 1.7699780113626 | 1.24486862306414 | 1.51418983280376 | 0.738111676571398 | 1.04218579419742 | 1.22156488555217 | 1.12867755953087 | 1.24932117077303 | 0.942550937445138 | 0.990334595417959 | 1.17610605790823 | 0.880125732655817 | 1.0590308620143 | 0.850345110763933 | 0.709200343174384 | 1.09091509214127 | 0.994676358686918 | 1.10714189213457 | 0.963744331308925 | 0.902694362008174 | 0.984002688464624 | 0.968382241573663 | 1.07684235664614 | 1.0681926712546 | 1.00501518686425 | 0.822807770853016 | 1.09914314538451 | 1.11675901669342 | 0.987533829206112 | 1.02995670029441 | 1.03452087538245 | 1.49356336942089 | 1.32117432578269 | 1.00304520710784 | 0.940016287549794 | 0.999143254540612 | 0.958284602169236 | 1.02858213779168 | 1.06794460638163 | 0.829980099801736 | 1.0385009075751 | 1.03830386424323 | 1.10981332344941 | 1.01100414956778 | 1.05406920590435 | 1.23288285463388 | 0.969718131178683 | 1.04020454861863 | 0.770496777768832 | 1.04775615260854 | 0.945575443289531 | 1.05542176115651 | 1.04103600897578 | 1.82535084495077 | 1.10921185156056 | 0.970946076552293 | 1.34648531090398 | 1.0980935965318 | 0.67949942833772 | 0.895889703266283 | 1.2048489551096 | 1.12959165172785 | 1.04023023590877 | 0.856206397718287 | 1.74879849118565 | 1.26111116999378 | 1.19979067645701 | 1.03794627530791 | 1.49534702975943 | 1.133361179877 | 1.03256237848084 | 1.0155180711977 | 1.103825998734 | 0.934862302574308 | 1.38135650907417 | 1.16328444620823 | 0.94728377547068 | 1.02022531273482 | 0.990126022329576 | 1.00360148410621 | 1.00250567215313 | 1.00646441827976 | 0.934888532754183 | 1.7321254860684 | 0.995588764663682 | 1.88118733208289 | 1.00151479441445 | 1.11457208021441 | 0.987647340080493 | 1.03617035250417 | 0.999992000022181 | 1.02421181683908 | 1.0168598785438 | 1.01356164808002 | 1.03873852242202 | 1.15981512713411 | 1.02324123942833 | 0.872960704329724 | 1.19268609624202 | 1.05963215036771 | 1.02688747339214 | 1.01600581397867 | 0.992594604161092 | 0.929559330052584 | 1.07468327512226 | 0.92359679498981 | 1.25863667463907 | 1.35808731829873 | 0.999912502653454 | 1.07256487598495 | 0.938293825569776 | 0.895937812968357 | 0.781422042864905 | 0.969666256368003 | 1.06727126581454 | 1.00431042006384 | 0.796325593432431 | 0.953058436711357 | 1.07378486863574 | 1.24851081996449 | 1.22531492379097 | 1.05623344396452 | 1.24343788042878 | 1.7407495224748 | 1.11076614163688 | 1.50560991293062 | 0.814910059277797 | 1.06754313439471 | 1.16644276225854 | 0.986463110728746 | 0.995138219635573 | 0.925981462943821 | 0.992367795516372 | 1.04292929566347 | 0.964654376535804 | 1.02492160197819 | 2.02148074269903 | 0.974896774283254 | 0.999887004425398 | 1.08239108476766 | 0.998527751970639 | 1.12412524144632 | 1.06144938202996 | 1.0566259436649 | 1.22980406808591 | 0.971428151755432 | 1.03513774665464 | 0.992730408158546 | 1.13754584835795 | 1.28188005893151 | 1.01652911639496 | 1.38569142157655 | 0.905659699318919 | 0.794820375716655 | 0.815425026685999 | 0.628533659836357 | 1.01419465063707 | 1.23573692657644 | 1.26676953641765 | 1.11728288107871 | 1.49310684429578 | 1.03998211479283 | 1.11323256631969 | 1.2736110358244 | 1.15016506302892 | 1.04603841542198 | 1.12549074532507 | 1.04600902058654 | 0.914903375411228 | 0.970625275974594 | 1.06392641215435 | 1.10623290944631 | 0.961857438777409 | 1.17184819525634 | 0.790925910692695 | 1.10609850571806 | 0.99690532627352 | 1.09193934910691 | 0.928437906347606 | 0.691681047618976 | 0.968780769844042 | 0.996589540631954 | 1.04440656482547 | 1.01657108974847 | 1.22398593832425 | 1.29567848415332 | 1.00211805250088 | 1.02796794451014 | 1.03275356400629 | 1.00282425902285 | 1.23782607546017 | 1.04632465769353 | 1.11494292153196 | 1.1735853219443 | 1.06075576388407 | 1.01033173199204 | 1.03747697134662 | 1.02174240701236 | 1.32391290369172 | 0.991163727215665 | 1.15392384890449 | 1.18213822661254 | 0.973973088867229 | 1.36399032044946 | 0.98479943182168 | 1.2192661097143 | 0.406009867506501 | 1.02075974549882 | 0.995485585325798 | 0.858108887074929 | 1.30636443468779 | 1.43426450658147 | 1.10996359109065 | 1.13721914392867 | 0.980364961904884 | 1.03690528326878 | 0.930998841435983 | 1.20931464426876 | 1.03334721137299 | 1.08012386456182 | 1.18612198500874 | 0.890984930174497 | 1.39188306608117 | 1.00653322615365 | 1.0348136659107 | 0.960786355482354 | 1.19089479742657 | 1.01481378257801 | 1.16325400368601 | 0.992410070711343 | 0.897174038282311 | 0.975371377254896 | 1.03265285631146 | 1.03976895810754 | 0.949844818550824 | 1.22665398788078 | 1.02408931647127 | 0.877080314070628 | 1.07716794334609 | 0.945441793805665 | 1.01237764583746 | 1.04946443736758 | 0.973383645417318 | 1.01119762125123 | 0.916481805058516 | 1.37115483463662 | 1.37977110194736 | 1.08504576073436 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PHGDH | DNA mutation status | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PHGDH | RNA expression | 7.92011461984654 | 8.22168378101097 | 5.66192057913509 | 8.82683445576123 | 0.575312330687437 | 6.8801957289431 | 7.92267359284945 | 7.97229057308727 | 6.87528859822269 | 6.26566192452189 | 0.37851162325373 | 7.37277801706204 | 6.75288236627309 | 2.43295940727611 | 8.35226417325832 | 7.53239489019252 | 9.02832050455748 | 6.16812050459556 | 8.3990856235724 | 5.02014657311178 | 7.55596949459953 | 8.24773767265893 | 6.4317900833788 | 6.58255600301406 | 6.09444722169991 | 7.56871618873173 | 5.54318652456517 | 5.93215568443206 | 2.48026512205446 | 4.7771566660045 | 0.0285691521967709 | 6.65721124844379 | 5.10559427579519 | 8.96046537410255 | 8.2319411483087 | 7.15674042118313 | 5.81659970653491 | 8.08544590219427 | 7.35491051158679 | 7.55834417569254 | 0.933572638261024 | 0.687060688339892 | 6.92338691550471 | 8.08342613943746 | 7.60673831741759 | 7.93934413283448 | 7.36981542428391 | 8.52454171503585 | 8.97033601304213 | 8.52120781622399 | 6.57939137064274 | 7.14618679149074 | 5.23381138429316 | 6.91910167955939 | 6.04111153536915 | 6.95547555318157 | 8.47674620393947 | 2.28983446517751 | 5.88484209379946 | 7.73077579651205 | 6.19258872156664 | 7.18705508996806 | 8.39964108969106 | 7.29746657376321 | 6.32912359629157 | 8.13852780142227 | 9.13883494297137 | 7.75181181986212 | 0.411426245726465 | 7.45030398982412 | 6.30597052098439 | 5.48864353985378 | 5.8040019151793 | 8.06447332875342 | 8.18839103334069 | 4.72191944555154 | 6.52277766952458 | 6.49265437101891 | 7.18576745571063 | 3.93357263826102 | 6.06371864015225 | 7.17422662975546 | 2.03210084316702 | 8.15284254277389 | 5.52575569282949 | 7.29700794927485 | 4.91217080294995 | 5.98162436069636 | 7.03353312672669 | 6.59738218934868 | 8.81775115033904 | 6.92754094958947 | 7.03957710306068 | 5.34340782229781 | 9.12306087745205 | 3.21723071622067 | 7.1509657835565 | 7.56017995776418 | 5.83668159332712 | 5.85349670370232 | 6.72437742160622 | 6.66006722293064 | 5.6906964439777 | 6.50048340147312 | 7.54743440510667 | 6.14913740122799 | 6.25455625190949 | 7.02901108665907 | 5.98002530023873 | 5.12474169241965 | 8.11535583172111 | 2.72900887033786 | 6.6514822821509 | 3.5298209465287 | 7.79298545968466 | 8.26617748242578 | 0.464668267003444 | 8.36115424129828 | 7.61823865559545 | 7.63705953841085 | 8.40654517342795 | 5.67355642399014 | 7.62512434187511 | 5.14323013477689 | 0.0565835283663675 | 5.7045953476324 | 6.73159057159445 | 1.79493566280354 | 6.14751022492028 | 7.65420637794429 | 0.910732661902913 | 4.60584986719498 | 5.01569380710515 | 5.71890955437923 | 4.70265754339091 | 6.98959318493877 | 7.50604966825032 | 7.76095275554585 | 7.43011797489203 | 6.51522674595618 | 4.75968848842729 | 0.622930350920177 | 6.24203080192273 | 7.40335294519078 | 1.51601514700367 | 4.38128337250378 | 5.35684807923652 | 6.22708641687464 | 5.03430376776804 | 6.39643353125099 | 6.28336621294992 | 6.89929649464017 | 6.19888699095693 | 6.01145091173575 | 6.90917305628501 | 3.68257329734758 | 6.37937836707126 | 8.69393990656978 | 7.01625115501275 | 5.79285535236249 | 4.91456452349394 | 4.23266075679027 | 7.54720302475693 | 5.27426166125705 | 7.51024988749149 | 4.74362267606766 | 6.06953032516231 | 5.22573765346606 | 6.57773093149008 | 7.06695024392463 | 5.82603995889619 | 7.4463389508575 | 9.40282021975662 | 8.04001567884788 | 8.59208323365389 | 5.58044701959866 | 8.15061044620011 | 4.16188768237689 | 8.0359537565578 | 5.5677279633048 | 7.13288525362516 | 7.00887676839426 | 5.96532254836725 | 7.881970449996 | 8.63792898100901 | 8.55826763405574 | 4.8171115727957 | 7.91318861950889 | 8.67891698667984 | 8.26500549334373 | 7.08725066461331 | 6.97613447283165 | 8.17317741512042 | 8.77049872089289 | 7.07863118123353 | 7.0458142561885 | 6.61294219630467 | 6.84724530714181 | 8.58803997108383 | 7.78404587023157 | 6.66831771991572 | 7.10622267291912 | 0.823749360308273 | 7.56040926636212 | 8.62928375485366 | 0.632268215499513 | 7.80077050442796 | 6.6573541815237 | 6.6477462172081 | 7.20633064787105 | 4.34340782229781 | 7.4606606646076 | 6.71328340023074 | 6.36404708360732 | 8.65209206611829 | 7.79772636462328 | 7.65492239118093 | 6.82959589917751 | 5.36876834909033 | 5.92908083524258 | 6.4432751117658 | 6.96589969564898 | 7.46703487987036 | 8.83364912759498 | 5.7311832415722 | 7.17791779219584 | 8.14908657973822 | 5.30085587126876 | 6.87061131304455 | 7.40386417660679 | 7.39591965945896 | 7.58736499093646 | 7.22833771198138 | 7.55197736018086 | 5.3547342399706 | 5.970163424661 | 7.49849023290861 | 6.23112515787905 | 8.36505383393081 | 5.20789285164133 | 7.27314285930808 | 3.51727569320958 | 6.09360242879573 | 6.61102479730735 | 5.76128527336162 | 0.903038270112912 | 8.46634161957308 | 6.18982455888002 | 8.01920150956739 | 8.38292658257124 | 3.93734439215023 | 5.5894638929561 | 8.14435233866261 | 6.8891084419241 | 0.678071905112638 | 8.00943675560809 | 8.95309059621739 | 6.09021830165332 | 6.94988505922693 | 8.99590844611722 | 6.40173284952262 | 5.10139795218253 | 5.92005505480697 | 6.52497259828663 | 7.45294130797121 | 8.78440582816822 | 9.32840565895857 | 8.86195536414487 | 7.45442268349988 | 8.48381577726426 | 7.15653819311427 | 7.55274593674845 | 6.83529250438005 | 5.75755668893945 | 3.74953426766926 | 3.44625622988956 | 6.61926626848919 | 7.30587934677885 | 7.04231601689711 | 5.67044381212281 | 7.15956864173076 | 7.28197637785875 | 5.8073549220576 | 7.19051609621556 | 7.44003860049473 | 8.646990644004 | 0.565597175854225 | 6.1586601753465 | 1.81147103052984 | 8.36260138753113 | 1.14404636961671 | 7.80316244441589 | 8.93484081203836 | 7.93787400508494 | 7.58998814168542 | 7.23620558153169 | 7.83491342970104 | 0.992768430768924 | 8.52532504343348 | 6.33431798469344 | 8.09508049190141 | 7.81281907378165 | 8.48727731321378 | 0.432959407276106 | 6.22149045504206 | 6.66647256884207 | 8.02053553705529 | 5.62673115067279 | 3.90207357931074 | 8.54747296489073 | 6.12453492852952 | 8.21626083716506 | 0.485426827170242 | 7.47800105583793 | 0.84799690655495 | 8.4989289663195 | 6.46090634820725 | 6.86666075081999 | 8.16857184044811 | 8.80183767032362 | 7.57939137064274 | 8.73552217729654 | 8.48220292629595 | 3.6915341649192 | 6.0723202160327 | 7.76877980990854 | 7.80264560412882 | 5.08746284125034 | 5.7967534769737 | 5.75728999237877 | 4.22650852980868 | 4.83187724119167 | 3.86195536414487 | 7.97229057308727 | 8.38650920407794 | 9.47185807963841 | 7.82145511910246 | 7.64558638591361 | 7.54303182025524 | 7.12494842668108 | 6.02369891726641 | 7.91731240109503 | 4.06004738366994 | 8.86102485326131 | 5.98686597232911 | 5.69488019279919 | 5.27984269352035 | 6.50937914891469 | 8.82638959142194 | 8.92964307602784 | 8.36387192485753 | 7.9258214435525 | 5.29645740737124 | 8.25356388069302 | 8.65638910831078 | 6.90436366757948 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PHGDH | CRISPR gene dependency | 0.07 | 0.03 | 0.04 | 0.03 | 0.29 | 0.06 | 0.06 | 0.01 | 0.16 | 0.02 | 0.00 | 0.18 | 0.05 | 0.05 | 0.01 | 0.07 | 0.47 | 0.17 | 0.01 | 0.05 | 0.02 | 0.39 | 0.02 | 0.09 | 0.14 | 0.03 | 0.16 | 0.31 | 0.08 | 0.05 | 0.02 | 0.04 | 0.17 | 0.05 | 0.04 | 0.04 | 0.06 | 0.16 | 0.03 | 0.09 | 0.14 | 0.09 | 0.35 | 0.07 | 0.02 | 0.17 | 0.01 | 0.19 | 0.01 | 0.03 | 0.14 | 0.06 | 0.07 | 0.19 | 0.05 | 0.02 | 0.08 | 0.05 | 0.04 | 0.18 | 0.02 | 0.03 | 0.08 | 0.10 | 0.04 | 0.00 | 0.02 | 0.02 | 0.03 | 0.08 | 0.04 | 0.08 | 0.02 | 0.07 | 0.15 | 0.01 | 0.05 | 0.05 | 0.02 | 0.03 | 0.13 | 0.04 | 0.04 | 0.03 | 0.12 | 0.12 | 0.11 | 0.07 | 0.04 | 0.05 | 0.03 | 0.01 | 0.05 | 0.61 | 0.04 | 0.06 | 0.05 | 0.02 | 0.24 | 0.01 | 0.02 | 0.16 | 0.02 | 0.04 | 0.03 | 0.07 | 0.04 | 0.02 | 0.14 | 0.11 | 0.12 | 0.01 | 0.05 | 0.04 | 0.13 | 0.43 | 0.02 | 0.01 | 0.09 | 0.11 | 0.01 | 0.13 | 0.02 | 0.27 | 0.12 | 0.12 | 0.16 | 0.04 | 0.15 | 0.17 | 0.01 | 0.07 | 0.03 | 0.03 | 0.14 | 0.07 | 0.02 | 0.32 | 0.05 | 0.05 | 0.16 | 0.08 | 0.05 | 0.04 | 0.08 | 0.12 | 0.04 | 0.06 | 0.02 | 0.04 | 0.08 | 0.01 | 0.06 | 0.09 | 0.03 | 0.11 | 0.02 | 0.08 | 0.14 | 0.04 | 0.05 | 0.00 | 0.02 | 0.02 | 0.01 | 0.01 | 0.00 | 0.06 | 0.02 | 0.01 | 0.74 | 0.37 | 0.04 | 0.08 | 0.06 | 0.02 | 0.01 | 0.03 | 0.22 | 0.02 | 0.05 | 0.01 | 0.01 | 0.07 | 0.03 | 0.11 | 0.05 | 0.05 | 0.06 | 0.02 | 0.10 | 0.03 | 0.17 | 0.02 | 0.16 | 0.08 | 0.02 | 0.21 | 0.00 | 0.03 | 0.03 | 0.03 | 0.06 | 0.06 | 0.05 | 0.03 | 0.01 | 0.11 | 0.07 | 0.12 | 0.01 | 0.07 | 0.01 | 0.21 | 0.04 | 0.02 | 0.01 | 0.02 | 0.12 | 0.38 | 0.02 | 0.14 | 0.01 | 0.01 | 0.08 | 0.01 | 0.26 | 0.16 | 0.08 | 0.02 | 0.01 | 0.05 | 0.02 | 0.14 | 0.05 | 0.10 | 0.29 | 0.01 | 0.08 | 0.22 | 0.03 | 0.02 | 0.11 | 0.09 | 0.04 | 0.05 | 0.04 | 0.03 | 0.01 | 0.37 | 0.20 | 0.05 | 0.06 | 0.01 | 0.01 | 0.15 | 0.17 | 0.01 | 0.05 | 0.03 | 0.19 | 0.06 | 0.01 | 0.04 | 0.04 | 0.03 | 0.01 | 0.03 | 0.09 | 0.03 | 0.03 | 0.08 | 0.05 | 0.02 | 0.12 | 0.04 | 0.01 | 0.08 | 0.10 | 0.01 | 0.01 | 0.17 | 0.06 | 0.14 | 0.14 | 0.01 | 0.04 | 0.06 | 0.02 | 0.01 | 0.18 | 0.06 | 0.06 | 0.05 | 0.07 | 0.05 | 0.00 | 0.01 | 0.05 | 0.00 | 0.08 | 0.02 | 0.04 | 0.04 | 0.18 | 0.06 | 0.02 | 0.06 | 0.03 | 0.07 | 0.02 | 0.04 | 0.10 |
Structural information (To highlight a cysteine, click a "CYS" button)
Cysteine | Gene | Uniprot Accession | pdb | Depth (Å) | Absolute SASA (Å^2) | Half-Sphere Exposure (up) | Half-Sphere Exposure (down) | Coordination Number | Relative SASA | Estimated h_nho1 energy (DSSP) | Estimated h_ohn1 energy (DSSP) | Estimated h_nho2 energy (DSSP) | Estimated h_ohn2 energy (DSSP) | TCO (DSSP) | Kappa (DSSP) | Alpha (DSSP) | Phi (DSSP) | Psi (DSSP) | Structural Motif (DSSP) | Pocket Volume (Å^3) | Presence at Interface | Local Basic Content (Fraction of Local Neighbors) | Local Acidic Content (Fraction of Local Neighbors) | Local Polar Content (Fraction of Local Neighbors) | Local Cysteine Content (Fraction of Local Neighbors) | Local Structural Content (Fraction of Local Neighbors) | Local Aliphatic Content (Fraction of Local Neighbors) | Local Aromatic Content (Fraction of Local Neighbors) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PHGDH | O43175 | 6rj3 | 2.4 | 18.0 | 10.0 | 13.0 | 23.0 | 0.1 | -0.2 | -2.2 | -0.2 | -0.2 | 0.8 | 87.1 | 61.4 | -59.3 | -31.4 | H | 0.0 | 0.0 | 0.2 | 0.2 | 0.0 | 0.2 | 0.2 | 0.2 | 0.0 | |
PHGDH | O43175 | 6rj3 | 4.4 | 0.0 | 21.0 | 10.0 | 31.0 | 0.0 | -1.8 | -0.2 | -0.1 | -0.2 | -0.9 | 40.9 | -178.6 | -107.6 | 129.0 | N/A | 0.0 | 0.0 | 0.3 | 0.3 | 0.0 | 0.0 | 0.2 | 0.2 | 0.0 | |
PHGDH | O43175 | 6rj3 | 3.0 | 13.9 | 25.0 | 23.0 | 48.0 | 0.1 | -0.6 | -0.1 | -0.4 | -0.1 | 0.0 | 66.0 | 71.7 | -110.6 | 20.1 | N/A | 0.0 | 0.0 | 0.0 | 0.2 | 0.4 | 0.0 | 0.0 | 0.4 | 0.0 | |
PHGDH | O43175 | 6rj3 | 3.4 | 1.1 | 24.0 | 13.0 | 37.0 | 0.0 | -2.2 | -0.3 | -0.2 | -0.2 | -1.0 | 75.4 | -165.5 | -110.3 | 124.0 | E | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.4 | 0.5 | 0.0 | |
PHGDH | O43175 | 6rj3 | 7.2 | 0.0 | 27.0 | 23.0 | 50.0 | 0.2 | -1.6 | -2.0 | -0.3 | -0.1 | -1.0 | 41.0 | -106.1 | -141.2 | 156.0 | N/A | 0.0 | 0.0 | 0.0 | 0.2 | 0.2 | 0.0 | 0.2 | 0.4 | 0.0 | |
PHGDH | O43175 | 6rj3 | 3.0 | 1.3 | 26.0 | 15.0 | 41.0 | 0.0 | -2.7 | -2.2 | -0.2 | -0.2 | 0.9 | 109.1 | 52.4 | -63.2 | -41.6 | H | 0.0 | 0.0 | 0.1 | 0.1 | 0.2 | 0.0 | 0.3 | 0.2 | 0.0 |
Using this data? Please cite Takahashi, Chong, Zhang, et al. (2024) Cell
and Lawrence Lab