DrugMap cysteine engagement data for:

PHGDH Gene:

Probe:    KB05    KB03     KB02

Download Table Download Statistics

name	peptide	skin_A375	skin_RPMI7951	skin_SKMEL2	skin_HMCB	skin_SKMEL3	skin_G361	skin_UACC257	skin_SKMEL30	skin_MEWO	skin_UACC62	skin_LOXIMVI	skin_WM2664	ovary_TOV21G	ovary_OVTOKO	ovary_EFO21	ovary_OVK18	ovary_OV90	ovary_PEO1	ovary_OAW28	ovary_OVCAR4	ovary_SKOV3	ovary_OVISE	ovary_NIHOVCAR3	ovary_EFO27	bile_duct_ICC21	bile_duct_ICC137	bile_duct_ICC10	bile_duct_ICC106	bile_duct_SNU245	bile_duct_ICC11	bile_duct_ICC108	bile_duct_ICC24	bile_duct_TGBC1TKB	bile_duct_ICC20	bile_duct_ICC8	bile_duct_KMCH1	ovary_OVKATE	ovary_OVCAR5	ovary_A2780	ovary_CAOV3	ovary_MCAS	ovary_OVCA429	ovary_OAW42	soft_tissue_RKN	bile_duct_ICC26	bile_duct_TFK1	bile_duct_ICC3	bile_duct_ICC18	lung_MGH0061	lung_NCIH3122	lung_MGH0651	lung_MGH0261	lung_MGH0732	lung_MGH0653	lung_MGH9153	lung_MGH0752	lung_MGH97967	lung_MGH9521R	lung_MGH92431	lung_MGH91621	skin_COLO792	skin_MELJUSO	skin_COLO679	skin_A2058	skin_SKMEL28	skin_IGR1	skin_HS944T	skin_IGR37	skin_RVH421	skin_IPC298	skin_WM793B	breast_AU565	breast_CAL148	breast_ZR751	breast_MCF7	breast_HDQP1	breast_HCC1419	breast_CAL51	breast_MDAMB231	breast_BRX142JUNE	breast_BRX330FEB	breast_BRX50	breast_BRX82	breast_BRX394JUNE	breast_BRX29	breast_BRX330JAN	breast_BRX401	breast_BRX68	breast_BRX390	breast_BRX250MAY	breast_BRX211MAY	skin_MEL182	skin_MEL167	skin_IGR39	fibroblast_HS839T	blood_CMK	blood_THP1	blood_U937	blood_MONOMAC1	blood_KASUMI1	blood_MOLM13	blood_P31FUJ	blood_OCIAML5	bile_duct_SNU1079	bile_duct_RBE	bile_duct_YSCCC	bile_duct_ETK1	bile_duct_ECC2	bile_duct_EGI1	bile_duct_SNU869	bile_duct_SNU1196	bile_duct_OCUG1	bile_duct_GB2	bile_duct_SNU308	bile_duct_G415	lymphocyte_HT	lymphocyte_A3KAW	lymphocyte_RL	lymphocyte_KARPAS422	lung_MGH8022	lung_MGH8021	lung_MGH8091	lung_MGH9201	lung_MGH1701	lung_MGH100151	lung_MGH1542	lung_MGH100164	bile_duct_CCSW1	bile_duct_CCLP1	bile_duct_SG231	bile_duct_HUCCT1	skin_CHL1	skin_COLO829	skin_A375S2	skin_A101D	skin_SKMEL24	skin_SH4	skin_HS936T	lung_MGH90921	plasma_cell_KMS12BM	plasma_cell_KMS11	plasma_cell_KMS27	plasma_cell_RPMI8226	ovary_TYKNU	ovary_FUOV1	lung_ABC1	lung_A549	lung_HCC15	lung_CALU6	pancreas_CFPAC1	pancreas_BXPC3	pancreas_KP4	pancreas_HUPT4	breast_HCC1937	breast_HCC1806	breast_CAMA1	breast_BT549	breast_MDAMB436	lung_MGH1543	lung_MGH1541	lung_MGH8222	lung_MGH1904	bile_duct_TKKK	bile_duct_SNU478	bile_duct_HUH28	bile_duct_ICC12	lung_NCIH1703	lung_LU65	lung_NCIH1155	liver_HLF	liver_HUH7	liver_JHH6	liver_JHH1	bile_duct_HKGZCC	bile_duct_TGBC52TKB	bile_duct_ICC9	bile_duct_MG984	bile_duct_OZ	bile_duct_SSP25	bile_duct_ICC19	bile_duct_ICC4	brain_MGG75	brain_MGG23	brain_MGG123	kidney_KMRC1	kidney_CAKI1	kidney_KMRC20	kidney_786O	colorectal_SW403	colorectal_RKO	colorectal_MDST8	colorectal_SW948	uterus_HEC1	uterus_AN3CA	uterus_MFE296	uterus_RL952	lung_NCIH2172	lung_HCC44	lung_CORL23	lung_NCIH1299	colorectal_HCT15	colorectal_LS513	colorectal_HT115	colorectal_HT29	upper_aerodigestive_DETROIT562	upper_aerodigestive_BICR22	upper_aerodigestive_CAL27	upper_aerodigestive_HSC3	ovary_OV56	ovary_IGROV1	pancreas_SW1990	pancreas_DANG	pancreas_HUPT3	pancreas_PATU8988T	prostate_LNCAPCLONEFGC	prostate_DU145	prostate_VCAP	prostate_PC3	lung_NCIH1666	lung_NCIH23	lung_SW1573	lung_NCIH1944	lung_PC14	lung_HCC827	lung_LUDLU1	lung_NCIH1975	esophagus_KYSE150	esophagus_TE11	esophagus_KYSE30	esophagus_KYSE510	bone_CAL72	bone_U2OS	bone_SAOS2	bone_SJSA1	uterus_MFE280	cervix_SISO	uterus_ISHIKAWAHERAKLIO02ER	uterus_SNGM	lung_NCIH2170	lung_NCIH2122	lung_NCIH1792	blood_MOLM16	blood_MONOMAC6	blood_JURLMK1	blood_NOMO1	blood_KASUMI2	blood_697	blood_REH	blood_JM1	skin_WM115	skin_C32	skin_COLO853	urinary_tract_KU1919	urinary_tract_HT1376	urinary_tract_UMUC3	urinary_tract_J82	urinary_tract_RT112	urinary_tract_TCCSUP	urinary_tract_HT1197	urinary_tract_T24	breast_MDAMB453	breast_DU4475	breast_CAL120	lung_NCIH1048	lung_SW1271	lung_NCIH446	lung_NCIH2286	thyroid_8505C	thyroid_8305C	thyroid_FTC133	thyroid_CAL62	breast_MDAMB157	breast_HCC1143	breast_MDAMB468	central_nervous_system_GB1	central_nervous_system_KNS81FD	central_nervous_system_LN229	central_nervous_system_T98G	liver_SNU449	liver_SNU423	liver_HUH1	liver_JHH4	liver_SKHEP1	liver_JHH7	liver_HEP3B217	liver_HEPG2	skin_COLO800	skin_SKMEL5	esophagus_KYSE180	esophagus_KYSE410	esophagus_TE4	esophagus_TE1	ovary_KURAMOCHI	ovary_OVCAR8	pancreas_PANC0403	pancreas_MIAPACA2	pancreas_SUIT2	blood_MV411	blood_KO52	blood_TF1	blood_OCIAML2	cervix_HT3	cervix_CASKI	cervix_C4II	cervix_DOTC24510	lymphocyte_SUDHL4	blood_NALM6	lymphocyte_JEKO1	blood_JVM3	skin_A431	esophagus_OE33	esophagus_TE10	lymphocyte_OCILY3	blood_MEC1	blood_HG3	lymphocyte_SUDHL6	breast_HS578T	breast_KPL1	breast_HCC1954	breast_HCC1395	colorectal_COLO678	colorectal_LS123	colorectal_SW1116	colorectal_CCK81	bone_SKNMC	bone_A673	bone_SKES1	bone_TC71	central_nervous_system_DAOY	central_nervous_system_D283MED	central_nervous_system_PFSK1	central_nervous_system_ONS76	uterus_SKN	uterus_MFE319	kidney_OSRC2	kidney_769P	kidney_RCC10RGB	lung_NCIH1793	lung_NCIH1650	lung_CALU1	lung_NCIH358	skin_WM1552C	skin_MELHO	lung_NCIH2052	lung_MSTO211H	lung_CORL88	lung_SBC5	gastric_KATOIII	gastric_MKN45	gastric_OCUM1	gastric_SNU1	peripheral_nervous_system_SKNAS	peripheral_nervous_system_KPNYN	peripheral_nervous_system_NB1	peripheral_nervous_system_KELLY	kidney_G401	soft_tissue_A204	soft_tissue_KYM1	kidney_G402	lung_NCIH196	lung_NCIH146	lung_SHP77	lung_NCIH82	gastric_HGC27	gastric_AGS	gastric_NCIN87	gastric_IM95	upper_aerodigestive_FADU	upper_aerodigestive_CAL33	upper_aerodigestive_SCC25	upper_aerodigestive_HSC4	cervix_SW756	bone_CAL78	lymphocyte_KARPAS299	gastric_MKN1	plasma_cell_OPM2	plasma_cell_SKMM2	soft_tissue_HT1080	central_nervous_system_LN18	breast_HCC1187	breast_HCC70	blood_HEL9217	blood_HEL	blood_EOL1	gastric_SNU5	gastric_NUGC3	soft_tissue_RD	soft_tissue_RH30	soft_tissue_RH41	lymphocyte_REC1	esophagus_TE8	pancreas_PANC1	kidney_KMRC3	lung_NCIH2291	lymphocyte_L428	unknown_HDMYZ	skin_MCC13	skin_MCC26	prostate_22RV1	kidney_A498	kidney_VMRCRCW	colorectal_SW837	colorectal_LS180	colorectal_SW620	colorectal_COLO320	central_nervous_system_SF295	central_nervous_system_A172	central_nervous_system_GAMG	central_nervous_system_KNS42	blood_JURKAT	blood_PF382	lymphocyte_DEL	blood_SUPT1	central_nervous_system_SW1783	central_nervous_system_42MGBA	central_nervous_system_U87MG	central_nervous_system_U118MG
CYS 18	VLISDSLDPCCR	37	33	45	32	21	41	41	36	72			-10																																																																			22													26	20	13	7																																																																																																																																																																																	-4	2		14	25	29	83											57	29	40	42																																																		20	-4																	44	36	29	35
CYS 48	EELIAELQDCEGLIVR	-2	1	42	11	33	-42	16	-5	28	11	35	9	-7	22	26	-9	-20	0	-16	-17			39		23	60	74	37		16	34	18		28	49	28		-21	11	49	9	33	8	8	34		4		35	-21		43	6		12	9					13	-3	-9	-23	-14	-4	-15	7	6	-13	21	-23	-37	15	-35	-25	-26	18	12	-8	-38	4	-5	8	-46	12	-30	-38	31	-34	-17	-36	-41	33	-14	-19	4	21	-32	51	-6	-17	21	15	17	6	8	27	-12	9	-15	36	38	28	17					39	60	8	35	20	41	70	53		-42	-6	12	-32	-12	-5	13	0	-37	0	41	46	-9	23	39	53	42	-37	35	-17	45	26	43	-15	37	51	25	20	11	17	41	51	27	7	39	28		69	-1	9	-31	39	80	4	40	6	0	12	45	-13	-12	18	50	-33	-35	-36	40	-18	-18	67					24	53				-23							39	21	8	8	4	1	1	-7	-26	-9	50	37	1	38	18	-10	-2	41	7	-17	-9	-3	16	37	8	20	65	48	8	35	-20	21	8	6	11	7	16	23	1	27	3	19	1	8	-5				16	25	4	-11	43	30	16	17	-25	13	0	53	47	38	41	18	36	25	13	26	47	-10	-4	35	17	31	16	27	9	36	26	55	39	44	-7	-6	1	2	0	24	28	32				56	46	54	-18	14	16	-8	32	4	-39	7	7		19	40	55	-2	24	15	-7	-5	-2	-15	-21	20	-8	-26	-4	9	11	-23	18	40	-4	9	-3	-1	7	-11	31	2	-5	47	20	29	25	-7	27	13	6	15	5	-24	-7	27	15	18	10	10	-4	-16	4	17	8	-25	56	-35	19	30	-6					-20	-21		-24	2	-28	-15	1	-13	-13	-23	-1	-35	18	10	-12	-20	-13		-6				38	-19	11	-27	-21			-3	8	10	12	20	64	30	53	-9	-2	-27	-36	4	58	-14	3
CYS 234 *	VVNCAHGGIVDEGALLR						20	3	35	55	47		78					38	38	32	21			56		57	65	19	35	48	79	39	45						39	45	52									45		39										19	39	51	44	44	60	42	46	41	36		35	53	31	24	33	40	46	29	12	32	27	26					-8		45	36			38		40	45	35	31	41	29	38	25	54	35	45	40	-13	-3	22	18	-1		16		73	43	12	34					41	48	64	22								31									96	60			31						41	22	28	40	17									31		28	44	75	32	27						7	35	62	37	39	31		-4	15						32	39	40	40		30			31	62	29	35	33		11	18	27	38	34	30	28	37					25		26	50	35	39	45	44	27	43	-10	3	57	12	54	42	-14	17	-8	25	11	37	18	16	30	24	16	27	37	12	27	29	29	19	-5	20	14	31	45	48	47	22	21		34					18	32	66	18	38	28	24	12	41	22	30	41	41	29	37	28	43	37	22	24	34	23	33	10	46	40	31				49	59	25	17					1	19	34	32		25	53	37	27	46	32	30	15	19	17	13	20	11	19	27	31	23	1	3	10	-3	9	12	26	38	29	29	20	32	39	35		30	9	27	9	12	21	21	8	29	11	-8	24	31	27	27	41		1	26	15	17	-2		23	27					19	26		27	29	23	29	28	4	52	27	60	27	48	45	7	24	16	30	46	18	60	30	22	37	14	30	34	45	27	-12	25	19	-6	28	31	43	28	17	34	15	32	6	44	22	22
CYS 254	ALQSGQCAGAALDVFTEEPPR	40	34	33	35	38	7	-20	20	39	40	37	35	24	15	32	10	27	4	11	-1	35	15	36	7	50	40	22	30		29	26	52			14	22	42	12	49	44	28	35	33	34	30	13	8	16	29	8	32	42									17	15	29	25	18	22	18	31	24	8	23	32	27	20	20	1	19	19	18	12	42	24	26	20	37	15	37					19	20	26	35	30	36	27	31	34	38	24	34	30	24	27	6	21	1	5	20	27	8	23	31	6	47	11	53	20	61	15	40	35	35	43	31					-4	27	13	23	11	1	37	56	37	23	32	49	56	37	15	39	9	38			21		33	27	36	18	18	42	18	33	36					22	10	14	19	32	31	10									8	6	9	24	-7	-4	26					23	43			0	27	15	17	-20	7	5	3	18	10	7	3	11	10	28	20	5	25	28	25	3	32	20	26	1	33	22	11	14	14	10	38	17	22	55	25	42	36	-11	19	-3	9	11	28	22	20	35	24	20	24	29	13	20	46	33	25	-9	22	15	29	40	34	41	23	11	33	30	48	33	40	36	16	30	22	26	29	25	5	22	32	19	26	25	17	22	27	26	30	32	11	17	12	19	18	9	38	40	30	40	31	23	47	37	41	19	33	18	-4	31	24	5	15	16	42	21	41	36	10	42	29	24	8	9	-3	11	6	15	22	13	24	30	3	25	37	11	20	4	31	-5	18	11	25	16	41	25	37	31	9	6	13	13	19	20	0	20	23	0	17	16	21	4	25	7	30	18	4	21	-3	27	19	25					-6	6		5	8	-1	6	24	1	29	7	24	8	46	34	6	3	1	8	8				20	21	16	12	14	27	18	21	14	26	3	22	16	37	25	11	9	3	15	12	37	28	21
CYS 281	ALVDHENVISCPHLGASTK	42	40	48	48		-2	2	21	50	42	53	29	25	54	58	11	26	40	53	28	63	47	57	46	65	50	16	24	-5	15	20	30		29	33	20	51	21	44	50	30	50	41	36	61	12	0	32	39	34	11	59	29		70	45	8	16	27	45	31	25	41	26	23	48	28	43	42	29	37	45	53	43	38	16	33	54	28	36	55	41	62	45	71	37	63	5	44	20	45	39	42	53	49	40	53	28	32	58	48	33	46	41	54	42	27	53	40	36	38	36	48	41	37	79	64	37	37	43	57	43	41	44	25	48	35	50	55	41	25	33	44	41	48	47	22	26	56	51	24	36	67	75	44	27	63	37	64	56	71	42	62	77	47	48	45	46	65	55	45	31	69	54		64	59	15	33	66	61	44	57	50	62	-6	53	41	52	50	44	7	44	1	31	29	32	32	0	14	17	-10	49	42	-15	-16	2	55	17	16	-13	20	25	16	52	19	35	34	44	30	42	39	17	54	42	56	18	55	44	2	15	64	35	19	24	11	29	52	37	39	59	42	47	57	12	49	17	39	41	35	46	19	41	28	40	36	54	24	49	52	49	53	27	45	30	46	51	59	25	57	18	68	52	61		40	45	43	47	64	52	55	29	24	36	69	48	52	48	47	48	51	55	60	48	59	40	22	38	34	11	62	55	58	56	59	58	61	59	46	47	48	41	14	55	42	22	27	41	50	52	46	50	28	44	19	41	41	37	27	32	40	24	33	21	42	33	15	44	59	26	42	38	43	37	29	52	52	30	48	45	54	45	37	49	45	34	27	40	16	36	42	28	48	26	56	40	52	32	40	41	6	32	10	0	37	25	21	-1		34	22	32		29	33	20	34	41	15	29	16	39	17	57	40	38	32	32	30	16	26	55	51	54	30	36	36	21	46	26	37	37	33	24	47	45	52	52	33	32	11	25	44	54	56	54
CYS 295	CGEEIAVQFVDMVK	18	4	39	20		6		17	38	13	28	19					2	16	13	18	31	34	34	32	39	47	28	50							20	56		24	9	35	0	25	14	15	45		35																		21	17	21	18	28	-1	39	20	17	27	14	18	6	21	31	22	11	21	11	22	3	7	2	2	53	-1	0	7	11	35	11	15	33	55	40	17	26	19	16																	54	38	12	37	38	45	58	36					-8	2	19	23	11	13	15		28	19	22	53	31	30	1	52	7	40						33	70	31	32	33	42	26	15					31	20	3	49	69	33	49									15	28	20	22	13	20	17					19	20	-5	3									31	22	29	37	41	40	35	37	26	46	64	44	40	44	31	21	38	49	53	32	39	22	28	40	30	27	45	43	45	50	7	34	24	31				33	42	34	17	39	32	28	25				23	21	6	11	27	23	16	28	6	63	39	57	48	51	60	32	30	29	30	38	39	7	20	44	33	24	41	48	37	34	47	48	52	38	28	32	43	33	29	40	38	25				58	39	49	19	30	34	29	34	23	14	37	26		38	40	33	24	39	22	29	20	43	15	28	40	35	22	22	30	23	3	42	36	12	26	20	22				27	21	37	32	43	38	22	34	27	14	34	25	8	20	9	7	33	13	28	14	38	22	16	30	9	28	14	39	42	26						19		35	13	13	27	48	0	23	13	27	12			29	15	27		17	16			32	20	28	14	14	29	31	20	12	25	12					27	16	6	7
CYS 369	NAGNCLSPAVIVGLLK	82	83	86	90	35	82	79	85	90	90	81	70	84	70	79	87	93	87	83	87	85	79	84	94	95	88	86	83	75	64	63	91	4	77	26	26	85	82	92	88	87	53	72	93	45	80	85	86	74	92		93	72		76	86	91	86	92	91	14	19	81	90	94	94	88	93	69	91	42	96	97	84	87	91	92	89	57	76	91	82	94	88	94	84	74	87	43	87	97	92	96	84	92	93	77	70	39	72	62	86	93	29	81	64	76	56	88	78	87	73	71	87	92	73	88	92	58	45	74	90	90	93	91	83	85	75	81	89	92	94	96	94	86	85	94	81	95	86	84	94	97	82	85	97		94	95	92	92	95	93	86	77	60	79	83	89	87	94	94	74	90	94	89	93	89	97	85	55	94	85	63	82	7	55	47	85	83	74	90	84	88	39	85	89	74	89	92	69	93	78	79	87	90		71			78	67	36	72	84	58	82	80	82	86	75	85	91	93	88	88	85	72	57	19	83	75	75	87	86	81	81	81	89	88	83	92	67	83	91	81	85	74	92	87	87	88	86	86	93	78	75	89	83	90	93	76	91	84	81	79	69	72	75	77	88	63	77	92	64	79	63	87	89	76	85	65	58	92	92	83	89	87	76	68	88	77	70	75	68	79	91	80	86	79	89	84	87	86	72	69	74	71	90	80	90	80	82	89	85	45	91	92	74	69	81	80	56	87	57	34	80	75	77	88	86	72	76	90	85	87	90	91	64	82	86	79	87	82	88	92	89	73	81	79	85	23	80	92	87	85	92	39	79	92	88	78	93	88	94	84	90	83	27	89	93	94	91	91	86	65	84					86	85		85	8	85	86	85	86	88	85	73	84	70	83	91	90	91	72	86	84	56	65	52	78	77	68	83	54	80	86	89	92	96	93	88	75	84	87	89	87	88	83	75	87	85
PHGDH	DNA copy number	1.08577225133498	1.09292015984736	1.62045527571331	1.00205149574989	1.08010331123351	1.01771798009804	1.14883101272233	1.25458053307856	1.00558426590135	1.07995891833598	0.959886652963831	1.40148869008426	0.994039364576736	0.918070186230214	1.31181097348351	1.00533482728845	1.02075974549882	1.09301790145481		1.36402334135254	1.04527484794726	1.05158654013213	1.23448588773225	1.01441126669469		1.13779405403235	0.740448303816749	0.903875600319968	1.15488545568103		1.47104002110976		1.39466558133709		0.751813656090129	1.17072345873768	1.01664795970722	0.889527966023906	1.02852809908145	1.2513980800014	1.09856098692039		1.09491652138609	1.31230908382645		1.12457018233871	0.971782466339412														0.876482348997776	0.951018312818169	0.821767250070994	0.973435659515332	1.74131440304789	0.975598418429519	1.1286151541643	1.02481785873168	0.93878258553207	1.86449627859963		1.20292660626317	0.985861465655612	1.26367744230954	1.02997447700613	1.02105290324452	1.13197796861611	1.02551572172341	1.1983727842501															0.930405070634609	1.00475480967831	1.05030920544215	1.32659962401581	1.14334566981952	1.00077420762391	1.00452407122957	0.974120366033681	0.997344947607448	0.993548489900791	1.25483730055181	1.07275581528921	1.00220568352076		0.994884102952812	1.01510273258332	1.03613499870674	1.05470695916055	1.13589441456422	0.984943398031732	1.19658614784147	1.09675132047943	1.01268931866103	1.00685320037247	1.0150613061995	0.98191775815051									1.41459341894234	1.01287494168128	0.825965272431997	0.952052240385974		0.747865745378424		1.15920479649057	1.02158255977089	1.26349305871352	0.978845408465616		0.889822535238806	0.795782349883345	0.984650533756616	1.32188939480072	1.1653430079759	1.05375301888561	0.963975319362439	0.812766033180691	1.08070262765575	0.921536526646135	1.08847380219724	1.1622684995519	0.961846733520358	0.945076008767481	1.36493894531944	0.942182108574755	1.7699780113626	1.24486862306414	1.51418983280376					0.738111676571398	1.04218579419742	1.22156488555217	1.12867755953087	1.24932117077303	0.942550937445138	0.990334595417959	1.17610605790823	0.880125732655817	1.0590308620143	0.850345110763933	0.709200343174384	1.09091509214127	0.994676358686918			1.10714189213457		0.963744331308925				0.902694362008174	0.984002688464624	0.968382241573663	1.07684235664614	1.0681926712546	1.00501518686425	0.822807770853016	1.09914314538451	1.11675901669342	0.987533829206112	1.02995670029441	1.03452087538245	1.49356336942089	1.32117432578269	1.00304520710784	0.940016287549794	0.999143254540612	0.958284602169236	1.02858213779168	1.06794460638163	0.829980099801736	1.0385009075751	1.03830386424323	1.10981332344941	1.01100414956778	1.05406920590435	1.23288285463388	0.969718131178683	1.04020454861863	0.770496777768832	1.04775615260854		0.945575443289531	1.05542176115651	1.04103600897578	1.82535084495077	1.10921185156056	0.970946076552293	1.34648531090398	1.0980935965318	0.67949942833772	0.895889703266283	1.2048489551096	1.12959165172785	1.04023023590877	0.856206397718287	1.74879849118565	1.26111116999378	1.19979067645701	1.03794627530791	1.49534702975943	1.133361179877	1.03256237848084	1.0155180711977	1.103825998734	0.934862302574308	1.38135650907417	1.16328444620823	0.94728377547068	1.02022531273482	0.990126022329576	1.00360148410621	1.00250567215313	1.00646441827976	0.934888532754183	1.7321254860684	0.995588764663682		1.88118733208289	1.00151479441445	1.11457208021441	0.987647340080493	1.03617035250417	0.999992000022181	1.02421181683908	1.0168598785438	1.01356164808002	1.03873852242202	1.15981512713411	1.02324123942833	0.872960704329724	1.19268609624202	1.05963215036771	1.02688747339214	1.01600581397867	0.992594604161092	0.929559330052584	1.07468327512226	0.92359679498981	1.25863667463907	1.35808731829873		0.999912502653454	1.07256487598495	0.938293825569776	0.895937812968357	0.781422042864905	0.969666256368003	1.06727126581454	1.00431042006384	0.796325593432431	0.953058436711357	1.07378486863574	1.24851081996449	1.22531492379097	1.05623344396452	1.24343788042878	1.7407495224748	1.11076614163688	1.50560991293062	0.814910059277797	1.06754313439471	1.16644276225854	0.986463110728746	0.995138219635573	0.925981462943821	0.992367795516372	1.04292929566347	0.964654376535804	1.02492160197819	2.02148074269903	0.974896774283254	0.999887004425398	1.08239108476766	0.998527751970639	1.12412524144632	1.06144938202996	1.0566259436649	1.22980406808591	0.971428151755432	1.03513774665464	0.992730408158546	1.13754584835795	1.28188005893151	1.01652911639496	1.38569142157655	0.905659699318919	0.794820375716655	0.815425026685999	0.628533659836357	1.01419465063707	1.23573692657644	1.26676953641765	1.11728288107871	1.49310684429578	1.03998211479283	1.11323256631969	1.2736110358244	1.15016506302892	1.04603841542198	1.12549074532507	1.04600902058654	0.914903375411228	0.970625275974594	1.06392641215435	1.10623290944631	0.961857438777409		1.17184819525634	0.790925910692695	1.10609850571806	0.99690532627352	1.09193934910691	0.928437906347606	0.691681047618976	0.968780769844042	0.996589540631954	1.04440656482547	1.01657108974847	1.22398593832425	1.29567848415332	1.00211805250088	1.02796794451014	1.03275356400629	1.00282425902285	1.23782607546017	1.04632465769353	1.11494292153196	1.1735853219443	1.06075576388407	1.01033173199204	1.03747697134662	1.02174240701236	1.32391290369172	0.991163727215665	1.15392384890449	1.18213822661254	0.973973088867229	1.36399032044946	0.98479943182168	1.2192661097143	0.406009867506501	1.02075974549882	0.995485585325798	0.858108887074929	1.30636443468779	1.43426450658147	1.10996359109065	1.13721914392867	0.980364961904884	1.03690528326878	0.930998841435983	1.20931464426876	1.03334721137299	1.08012386456182	1.18612198500874	0.890984930174497	1.39188306608117	1.00653322615365	1.0348136659107	0.960786355482354	1.19089479742657	1.01481378257801	1.16325400368601	0.992410070711343	0.897174038282311	0.975371377254896	1.03265285631146	1.03976895810754	0.949844818550824	1.22665398788078	1.02408931647127	0.877080314070628	1.07716794334609	0.945441793805665	1.01237764583746	1.04946443736758	0.973383645417318	1.01119762125123	0.916481805058516	1.37115483463662	1.37977110194736	1.08504576073436
PHGDH	DNA mutation status	0	0	0		0	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0		0	0	0	0		0		0		0	0	0	0	0	0	0		0	0		0	0														0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0															0	0	2	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0									0	0	0	0		0		0	0	0	0		0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0					0	0	0	0	0	0	0	0	0	0	0	0	0	0			0		0				1	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
PHGDH	RNA expression	7.92011461984654	8.22168378101097	5.66192057913509	8.82683445576123	0.575312330687437	6.8801957289431	7.92267359284945	7.97229057308727	6.87528859822269	6.26566192452189	0.37851162325373	7.37277801706204	6.75288236627309	2.43295940727611	8.35226417325832	7.53239489019252	9.02832050455748	6.16812050459556		8.3990856235724	5.02014657311178	7.55596949459953	8.24773767265893	6.4317900833788		6.58255600301406	6.09444722169991	7.56871618873173	5.54318652456517		5.93215568443206		2.48026512205446		4.7771566660045	0.0285691521967709	6.65721124844379	5.10559427579519	8.96046537410255	8.2319411483087	7.15674042118313		5.81659970653491	8.08544590219427		7.35491051158679	7.55834417569254														0.933572638261024	0.687060688339892	6.92338691550471	8.08342613943746	7.60673831741759	7.93934413283448	7.36981542428391	8.52454171503585	8.97033601304213	8.52120781622399		6.57939137064274	7.14618679149074	5.23381138429316	6.91910167955939	6.04111153536915	6.95547555318157	8.47674620393947	2.28983446517751															5.88484209379946	7.73077579651205	6.19258872156664	7.18705508996806	8.39964108969106	7.29746657376321	6.32912359629157	8.13852780142227	9.13883494297137	7.75181181986212	0.411426245726465	7.45030398982412	6.30597052098439		5.48864353985378	5.8040019151793	8.06447332875342	8.18839103334069	4.72191944555154	6.52277766952458	6.49265437101891	7.18576745571063	3.93357263826102	6.06371864015225	7.17422662975546	2.03210084316702									8.15284254277389	5.52575569282949	7.29700794927485	4.91217080294995		5.98162436069636		7.03353312672669	6.59738218934868	8.81775115033904	6.92754094958947		7.03957710306068	5.34340782229781	9.12306087745205	3.21723071622067	7.1509657835565	7.56017995776418	5.83668159332712	5.85349670370232	6.72437742160622	6.66006722293064	5.6906964439777	6.50048340147312	7.54743440510667	6.14913740122799	6.25455625190949	7.02901108665907	5.98002530023873	5.12474169241965	8.11535583172111					2.72900887033786	6.6514822821509	3.5298209465287	7.79298545968466	8.26617748242578	0.464668267003444	8.36115424129828	7.61823865559545	7.63705953841085	8.40654517342795	5.67355642399014	7.62512434187511	5.14323013477689	0.0565835283663675			5.7045953476324		6.73159057159445				1.79493566280354	6.14751022492028	7.65420637794429	0.910732661902913	4.60584986719498	5.01569380710515	5.71890955437923	4.70265754339091	6.98959318493877	7.50604966825032	7.76095275554585	7.43011797489203	6.51522674595618	4.75968848842729	0.622930350920177	6.24203080192273	7.40335294519078	1.51601514700367	4.38128337250378	5.35684807923652	6.22708641687464	5.03430376776804	6.39643353125099	6.28336621294992	6.89929649464017	6.19888699095693	6.01145091173575	6.90917305628501	3.68257329734758	6.37937836707126	8.69393990656978		7.01625115501275	5.79285535236249	4.91456452349394	4.23266075679027	7.54720302475693	5.27426166125705	7.51024988749149	4.74362267606766	6.06953032516231	5.22573765346606	6.57773093149008	7.06695024392463	5.82603995889619	7.4463389508575	9.40282021975662	8.04001567884788	8.59208323365389	5.58044701959866	8.15061044620011	4.16188768237689	8.0359537565578	5.5677279633048	7.13288525362516	7.00887676839426	5.96532254836725	7.881970449996	8.63792898100901	8.55826763405574	4.8171115727957	7.91318861950889	8.67891698667984	8.26500549334373	7.08725066461331	6.97613447283165	8.17317741512042		8.77049872089289	7.07863118123353	7.0458142561885	6.61294219630467	6.84724530714181	8.58803997108383	7.78404587023157	6.66831771991572	7.10622267291912	0.823749360308273	7.56040926636212	8.62928375485366	0.632268215499513	7.80077050442796	6.6573541815237	6.6477462172081	7.20633064787105	4.34340782229781	7.4606606646076	6.71328340023074	6.36404708360732	8.65209206611829	7.79772636462328		7.65492239118093	6.82959589917751	5.36876834909033	5.92908083524258	6.4432751117658	6.96589969564898	7.46703487987036	8.83364912759498	5.7311832415722	7.17791779219584	8.14908657973822	5.30085587126876	6.87061131304455	7.40386417660679	7.39591965945896	7.58736499093646	7.22833771198138	7.55197736018086	5.3547342399706	5.970163424661	7.49849023290861	6.23112515787905	8.36505383393081	5.20789285164133	7.27314285930808	3.51727569320958	6.09360242879573	6.61102479730735	5.76128527336162	0.903038270112912	8.46634161957308	6.18982455888002	8.01920150956739	8.38292658257124	3.93734439215023	5.5894638929561	8.14435233866261	6.8891084419241	0.678071905112638	8.00943675560809	8.95309059621739	6.09021830165332	6.94988505922693	8.99590844611722	6.40173284952262	5.10139795218253	5.92005505480697	6.52497259828663	7.45294130797121	8.78440582816822	9.32840565895857	8.86195536414487	7.45442268349988	8.48381577726426	7.15653819311427	7.55274593674845	6.83529250438005	5.75755668893945	3.74953426766926	3.44625622988956	6.61926626848919	7.30587934677885	7.04231601689711	5.67044381212281	7.15956864173076		7.28197637785875	5.8073549220576	7.19051609621556	7.44003860049473	8.646990644004	0.565597175854225	6.1586601753465	1.81147103052984	8.36260138753113	1.14404636961671	7.80316244441589	8.93484081203836	7.93787400508494	7.58998814168542	7.23620558153169	7.83491342970104	0.992768430768924	8.52532504343348	6.33431798469344	8.09508049190141	7.81281907378165	8.48727731321378	0.432959407276106	6.22149045504206	6.66647256884207	8.02053553705529	5.62673115067279	3.90207357931074	8.54747296489073	6.12453492852952	8.21626083716506	0.485426827170242	7.47800105583793	0.84799690655495	8.4989289663195	6.46090634820725	6.86666075081999	8.16857184044811	8.80183767032362	7.57939137064274	8.73552217729654	8.48220292629595	3.6915341649192	6.0723202160327	7.76877980990854	7.80264560412882	5.08746284125034	5.7967534769737	5.75728999237877	4.22650852980868	4.83187724119167	3.86195536414487	7.97229057308727	8.38650920407794	9.47185807963841	7.82145511910246	7.64558638591361	7.54303182025524	7.12494842668108	6.02369891726641	7.91731240109503	4.06004738366994	8.86102485326131	5.98686597232911	5.69488019279919	5.27984269352035	6.50937914891469	8.82638959142194	8.92964307602784	8.36387192485753	7.9258214435525	5.29645740737124	8.25356388069302	8.65638910831078	6.90436366757948
PHGDH	CRISPR gene dependency	0.07	0.03	0.04				0.03	0.29		0.06		0.06	0.01	0.16	0.02	0.00	0.18	0.05			0.05	0.01	0.07	0.47		0.17	0.01	0.05			0.02		0.39		0.02	0.09		0.14	0.03	0.16	0.31		0.08	0.05		0.02	0.04														0.17	0.05	0.04	0.04		0.06	0.16		0.03	0.09		0.14		0.09	0.35		0.07	0.02	0.17															0.01			0.19	0.01	0.03	0.14	0.06	0.07		0.19	0.05	0.02		0.08	0.05	0.04	0.18	0.02	0.03	0.08	0.10	0.04	0.00	0.02	0.02									0.03	0.08	0.04	0.08					0.02	0.07	0.15			0.01	0.05	0.05	0.02		0.03	0.13	0.04	0.04	0.03	0.12	0.12	0.11	0.07	0.04	0.05	0.03	0.01					0.05	0.61		0.04	0.06	0.05	0.02	0.24	0.01	0.02	0.16	0.02	0.04	0.03			0.07		0.04				0.02	0.14	0.11	0.12	0.01	0.05	0.04	0.13	0.43		0.02	0.01	0.09	0.11	0.01	0.13	0.02	0.27	0.12	0.12	0.16	0.04	0.15	0.17		0.01	0.07	0.03	0.03	0.14	0.07		0.02	0.32	0.05	0.05	0.16	0.08	0.05	0.04	0.08	0.12	0.04	0.06	0.02	0.04	0.08	0.01	0.06	0.09	0.03	0.11	0.02	0.08	0.14	0.04	0.05			0.00	0.02		0.02	0.01	0.01	0.00	0.06		0.02	0.01	0.74	0.37	0.04	0.08	0.06	0.02	0.01	0.03	0.22	0.02	0.05	0.01	0.01	0.07	0.03	0.11	0.05	0.05	0.06	0.02	0.10		0.03	0.17	0.02	0.16	0.08	0.02	0.21	0.00		0.03	0.03		0.03	0.06	0.06	0.05	0.03	0.01	0.11	0.07	0.12	0.01		0.07	0.01	0.21	0.04	0.02	0.01	0.02	0.12		0.38	0.02	0.14	0.01		0.01	0.08		0.01	0.26	0.16	0.08	0.02	0.01	0.05	0.02	0.14	0.05		0.10	0.29	0.01	0.08	0.22	0.03	0.02	0.11	0.09	0.04	0.05	0.04	0.03	0.01		0.37	0.20	0.05			0.06	0.01	0.01	0.15	0.17	0.01	0.05	0.03			0.19	0.06			0.01	0.04	0.04	0.03	0.01	0.03	0.09	0.03	0.03	0.08	0.05	0.02	0.12		0.04	0.01	0.08	0.10	0.01	0.01	0.17	0.06	0.14	0.14	0.01	0.04	0.06			0.02	0.01	0.18	0.06	0.06	0.05	0.07	0.05	0.00		0.01	0.05	0.00	0.08	0.02	0.04	0.04	0.18	0.06	0.02	0.06	0.03	0.07		0.02	0.04	0.10

Structural information   (To highlight a cysteine, click a "CYS" button)

Using this data? Please cite Takahashi, Chong, Zhang, et al. (2024) Cell

       Bar-Peled Lab

and Lawrence Lab