DrugMap: SOX10 (KB02)

DrugMap cysteine engagement data for:

SOX10
Gene: 
   
Probe:   KB05
KB05
   KB03
KB03
   
KB02
KB02
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namepeptideinformation
skin_A375
skin_RPMI7951
skin_SKMEL2
skin_HMCB
skin_SKMEL3
skin_G361
skin_UACC257
skin_SKMEL30
skin_MEWO
skin_UACC62
skin_LOXIMVI
skin_WM2664
ovary_TOV21G
ovary_OVTOKO
ovary_EFO21
ovary_OVK18
ovary_OV90
ovary_PEO1
ovary_OAW28
ovary_OVCAR4
ovary_SKOV3
ovary_OVISE
ovary_NIHOVCAR3
ovary_EFO27
bile_duct_ICC21
bile_duct_ICC137
bile_duct_ICC10
bile_duct_ICC106
bile_duct_SNU245
bile_duct_ICC11
bile_duct_ICC108
bile_duct_ICC24
bile_duct_TGBC1TKB
bile_duct_ICC20
bile_duct_ICC8
bile_duct_KMCH1
ovary_OVKATE
ovary_OVCAR5
ovary_A2780
ovary_CAOV3
ovary_MCAS
ovary_OVCA429
ovary_OAW42
soft_tissue_RKN
bile_duct_ICC26
bile_duct_TFK1
bile_duct_ICC3
bile_duct_ICC18
lung_MGH0061
lung_NCIH3122
lung_MGH0651
lung_MGH0261
lung_MGH0732
lung_MGH0653
lung_MGH9153
lung_MGH0752
lung_MGH97967
lung_MGH9521R
lung_MGH92431
lung_MGH91621
skin_COLO792
skin_MELJUSO
skin_COLO679
skin_A2058
skin_SKMEL28
skin_IGR1
skin_HS944T
skin_IGR37
skin_RVH421
skin_IPC298
skin_WM793B
breast_AU565
breast_CAL148
breast_ZR751
breast_MCF7
breast_HDQP1
breast_HCC1419
breast_CAL51
breast_MDAMB231
breast_BRX142JUNE
breast_BRX330FEB
breast_BRX50
breast_BRX82
breast_BRX394JUNE
breast_BRX29
breast_BRX330JAN
breast_BRX401
breast_BRX68
breast_BRX390
breast_BRX250MAY
breast_BRX211MAY
skin_MEL182
skin_MEL167
skin_IGR39
fibroblast_HS839T
blood_CMK
blood_THP1
blood_U937
blood_MONOMAC1
blood_KASUMI1
blood_MOLM13
blood_P31FUJ
blood_OCIAML5
bile_duct_SNU1079
bile_duct_RBE
bile_duct_YSCCC
bile_duct_ETK1
bile_duct_ECC2
bile_duct_EGI1
bile_duct_SNU869
bile_duct_SNU1196
bile_duct_OCUG1
bile_duct_GB2
bile_duct_SNU308
bile_duct_G415
lymphocyte_HT
lymphocyte_A3KAW
lymphocyte_RL
lymphocyte_KARPAS422
lung_MGH8022
lung_MGH8021
lung_MGH8091
lung_MGH9201
lung_MGH1701
lung_MGH100151
lung_MGH1542
lung_MGH100164
bile_duct_CCSW1
bile_duct_CCLP1
bile_duct_SG231
bile_duct_HUCCT1
skin_CHL1
skin_COLO829
skin_A375S2
skin_A101D
skin_SKMEL24
skin_SH4
skin_HS936T
lung_MGH90921
plasma_cell_KMS12BM
plasma_cell_KMS11
plasma_cell_KMS27
plasma_cell_RPMI8226
ovary_TYKNU
ovary_FUOV1
lung_ABC1
lung_A549
lung_HCC15
lung_CALU6
pancreas_CFPAC1
pancreas_BXPC3
pancreas_KP4
pancreas_HUPT4
breast_HCC1937
breast_HCC1806
breast_CAMA1
breast_BT549
breast_MDAMB436
lung_MGH1543
lung_MGH1541
lung_MGH8222
lung_MGH1904
bile_duct_TKKK
bile_duct_SNU478
bile_duct_HUH28
bile_duct_ICC12
lung_NCIH1703
lung_LU65
lung_NCIH1155
liver_HLF
liver_HUH7
liver_JHH6
liver_JHH1
bile_duct_HKGZCC
bile_duct_TGBC52TKB
bile_duct_ICC9
bile_duct_MG984
bile_duct_OZ
bile_duct_SSP25
bile_duct_ICC19
bile_duct_ICC4
brain_MGG75
brain_MGG23
brain_MGG123
kidney_KMRC1
kidney_CAKI1
kidney_KMRC20
kidney_786O
colorectal_SW403
colorectal_RKO
colorectal_MDST8
colorectal_SW948
uterus_HEC1
uterus_AN3CA
uterus_MFE296
uterus_RL952
lung_NCIH2172
lung_HCC44
lung_CORL23
lung_NCIH1299
colorectal_HCT15
colorectal_LS513
colorectal_HT115
colorectal_HT29
upper_aerodigestive_DETROIT562
upper_aerodigestive_BICR22
upper_aerodigestive_CAL27
upper_aerodigestive_HSC3
ovary_OV56
ovary_IGROV1
pancreas_SW1990
pancreas_DANG
pancreas_HUPT3
pancreas_PATU8988T
prostate_LNCAPCLONEFGC
prostate_DU145
prostate_VCAP
prostate_PC3
lung_NCIH1666
lung_NCIH23
lung_SW1573
lung_NCIH1944
lung_PC14
lung_HCC827
lung_LUDLU1
lung_NCIH1975
esophagus_KYSE150
esophagus_TE11
esophagus_KYSE30
esophagus_KYSE510
bone_CAL72
bone_U2OS
bone_SAOS2
bone_SJSA1
uterus_MFE280
cervix_SISO
uterus_ISHIKAWAHERAKLIO02ER
uterus_SNGM
lung_NCIH2170
lung_NCIH2122
lung_NCIH1792
blood_MOLM16
blood_MONOMAC6
blood_JURLMK1
blood_NOMO1
blood_KASUMI2
blood_697
blood_REH
blood_JM1
skin_WM115
skin_C32
skin_COLO853
urinary_tract_KU1919
urinary_tract_HT1376
urinary_tract_UMUC3
urinary_tract_J82
urinary_tract_RT112
urinary_tract_TCCSUP
urinary_tract_HT1197
urinary_tract_T24
breast_MDAMB453
breast_DU4475
breast_CAL120
lung_NCIH1048
lung_SW1271
lung_NCIH446
lung_NCIH2286
thyroid_8505C
thyroid_8305C
thyroid_FTC133
thyroid_CAL62
breast_MDAMB157
breast_HCC1143
breast_MDAMB468
central_nervous_system_GB1
central_nervous_system_KNS81FD
central_nervous_system_LN229
central_nervous_system_T98G
liver_SNU449
liver_SNU423
liver_HUH1
liver_JHH4
liver_SKHEP1
liver_JHH7
liver_HEP3B217
liver_HEPG2
skin_COLO800
skin_SKMEL5
esophagus_KYSE180
esophagus_KYSE410
esophagus_TE4
esophagus_TE1
ovary_KURAMOCHI
ovary_OVCAR8
pancreas_PANC0403
pancreas_MIAPACA2
pancreas_SUIT2
blood_MV411
blood_KO52
blood_TF1
blood_OCIAML2
cervix_HT3
cervix_CASKI
cervix_C4II
cervix_DOTC24510
lymphocyte_SUDHL4
blood_NALM6
lymphocyte_JEKO1
blood_JVM3
skin_A431
esophagus_OE33
esophagus_TE10
lymphocyte_OCILY3
blood_MEC1
blood_HG3
lymphocyte_SUDHL6
breast_HS578T
breast_KPL1
breast_HCC1954
breast_HCC1395
colorectal_COLO678
colorectal_LS123
colorectal_SW1116
colorectal_CCK81
bone_SKNMC
bone_A673
bone_SKES1
bone_TC71
central_nervous_system_DAOY
central_nervous_system_D283MED
central_nervous_system_PFSK1
central_nervous_system_ONS76
uterus_SKN
uterus_MFE319
kidney_OSRC2
kidney_769P
kidney_RCC10RGB
lung_NCIH1793
lung_NCIH1650
lung_CALU1
lung_NCIH358
skin_WM1552C
skin_MELHO
lung_NCIH2052
lung_MSTO211H
lung_CORL88
lung_SBC5
gastric_KATOIII
gastric_MKN45
gastric_OCUM1
gastric_SNU1
peripheral_nervous_system_SKNAS
peripheral_nervous_system_KPNYN
peripheral_nervous_system_NB1
peripheral_nervous_system_KELLY
kidney_G401
soft_tissue_A204
soft_tissue_KYM1
kidney_G402
lung_NCIH196
lung_NCIH146
lung_SHP77
lung_NCIH82
gastric_HGC27
gastric_AGS
gastric_NCIN87
gastric_IM95
upper_aerodigestive_FADU
upper_aerodigestive_CAL33
upper_aerodigestive_SCC25
upper_aerodigestive_HSC4
cervix_SW756
bone_CAL78
lymphocyte_KARPAS299
gastric_MKN1
plasma_cell_OPM2
plasma_cell_SKMM2
soft_tissue_HT1080
central_nervous_system_LN18
breast_HCC1187
breast_HCC70
blood_HEL9217
blood_HEL
blood_EOL1
gastric_SNU5
gastric_NUGC3
soft_tissue_RD
soft_tissue_RH30
soft_tissue_RH41
lymphocyte_REC1
esophagus_TE8
pancreas_PANC1
kidney_KMRC3
lung_NCIH2291
lymphocyte_L428
unknown_HDMYZ
skin_MCC13
skin_MCC26
prostate_22RV1
kidney_A498
kidney_VMRCRCW
colorectal_SW837
colorectal_LS180
colorectal_SW620
colorectal_COLO320
central_nervous_system_SF295
central_nervous_system_A172
central_nervous_system_GAMG
central_nervous_system_KNS42
blood_JURKAT
blood_PF382
lymphocyte_DEL
blood_SUPT1
central_nervous_system_SW1783
central_nervous_system_42MGBA
central_nervous_system_U87MG
central_nervous_system_U118MG
CYS 22 CLSPGSAPSLGPDGGGGGSGLR161916181813122120813121919261318129213119343028231623112620
CYS 71 EQQDGEADDDKFPVCIR4632373939431236232022221419262754588184337374016505743
CYS 71 *
FPVCIR575142596865675561505167474352466059486250555146455634526548697054486663604151470415441595755574853605560565158665864486359663248656956665811245261536047605660626470666660521966577240515658665559655944333843436757534333554655
CYS 190 AAQGEAECPGGEAEQGGTAAIQAHYK-192614-129-14121411227-11-30-29-233-19-1530924-14-314111215211619-6214141272623252734-2212-41553-19
SOX10DNA copy numberinformation1.05237913141020.8921055324261151.727748467897131.672093993250491.044772369007421.157014303149630.9360479518908961.058272299572490.9705385991069181.547090145098640.7098009150198791.06659023127611.001295080763771.100720057052690.7607979147766590.9814764651889230.643969957229140.646236030081771.078283540080911.017610184082750.7635134322709220.6807989117606320.964610005757661.110913809935741.51662093715370.7372090252539871.106435874304790.8389425047351750.8123328242468720.9612989309186090.6845752748589480.6183534027590140.8455142908473390.9961815666061511.072924217582270.9145375933414431.031698767355110.8176157979395111.012234943965531.029366427878811.238848146134570.9447511641793691.268900246523090.9759026722486671.325866771164331.324864984176361.065067721401030.9375615022279491.400964855841551.179724194317750.9483027884622670.578756721242540.7063717754286270.5993989276555230.9126080571185151.014554685077560.9910767674368830.7495037846551461.14466349790161.013242726133450.9967985600096561.000578115784690.8655480890472130.99398658497791.019723506590230.9675327581807310.9860377236445240.9751925223722730.7667873582059060.8389579379776651.178433250888370.7230824966132790.9941792897277741.064499311747260.8981765091637750.8792442043617431.166888066108970.7521491876277921.149109931686691.002027923274070.971076866963231.026565164120610.9836185726185140.9695977454497570.9901985228419970.8055061465216920.9428910796743451.201840389831011.128418727775740.9929144854711991.347755603141141.187958595038090.8934062630898390.9368587199659640.9692542633212750.9974637333129120.8893788672494830.7819922156074690.7832964648126270.794490454301140.6340648339097290.7850492018010150.9201885746038680.858017432389250.8836065056386090.9300809637351590.8386382921212340.9510212092179361.053620861430740.9883276042702450.7363503913205281.066854665689681.274498416354621.00771200290960.9142122809163881.118043097036430.9484964692532191.296166889049621.069718195520251.080177620662941.04648972251851.222480709488820.9768802723712231.591376942882150.9842776154912790.84846015277051.150010681006761.008710638609560.7213511998861011.15391063458471.033558956047820.782514137500740.9748638626806921.021386706907970.7733168897017520.8891253488041580.9658773310792631.007250628861490.9917184069752320.8255795717889090.8858843784010010.7767087323016670.7790681236901980.9918720258112970.966110630648310.9681607780581470.7303292311686680.7578048997839240.9286908783365191.005408600448610.801076449040670.9836482303468911.005291167386091.055242770460391.01320034298410.6035947417407630.7674298868466510.9583574038416720.9444566619267340.7511896110393090.7492578639509920.8398829916624650.6697154293365920.9946150873560731.192872297203490.8033468704142280.712371181748231.068410812283760.9773688370900170.9157156075083860.7068136098220580.9557511083925441.201453778411911.124296275523810.8715673577109711.018145192766140.8809027940235390.8497676384665980.991674163842240.9342782204969851.05709904757220.8805998590692360.9229581904461170.9033461547725670.6188014657481231.017538324439620.9934758189233991.00718781689371.00841791626361.0110243016760.9436873235333851.002700522778391.294148805638270.9511201732865941.00453610885070.9015771929653140.7442786101757220.9806505239249260.9753846448776440.7119410713021691.094743683544721.256062918704690.977020477395170.7709636335626321.000403556426430.871163857690540.9462549547606130.6096888859959840.7590187849620681.304275881594160.9531430455144890.9835676616392661.002082500857551.317763610540111.100519391922421.139880386178151.183699904283941.075962709722140.8753869251928461.009206187305240.7934801534993321.058203168605450.9952493475632591.359553386176791.050100296891210.950484516226781.101609467770851.136540842929330.8481556263059621.005010169521771.242184233353761.070181114826090.8343162708730460.8758000383000711.071293406155080.7575687543444840.8422362811515520.9721854070216211.004728724363290.9187402860718241.011380032016311.059491690353290.8855673580727061.004956485041991.016062938453290.9777443558474851.000347041730580.6686287534715780.9910708046750441.086573143302631.055570157463511.438217559023311.168687040622280.9821429005070191.018841449286460.9858778032536131.303718963902580.6457011223632170.7610061301339011.243275571664280.5136365095804090.7502192085759940.7947030491466711.035293411993831.00773914710710.9050393246867240.9478490489928531.021285238893050.9486472898308071.039359164721850.8968772505989240.8591355516168310.8181181858010271.001260550220161.130611081120561.022490619037521.09601513231060.9408247028166580.999254192873740.7771001316478250.8786428872728811.509946059760680.9543537732896620.6785608909711010.6704057128900840.9954825947310810.955426581224260.6173529127220490.9576111288276930.9955972386590460.6226676493224671.025162680299281.078509911518541.278925215922260.9990343234072010.9977372772148650.9974732166284430.9781485325858610.9356007627330930.7683201197840740.9665587939322190.8348047125887770.9873975290285890.9667130974138881.036083762782540.9874386655197061.357209232040460.9896722331981970.9145530864773550.8778412919190520.9275668815240461.404779125501531.018450492570970.7541354613512680.9419169411669060.9580899981590281.004157974609920.7739623080688610.8717496573870061.156081859700950.8334453308258880.8120530093422230.9725212803310591.001316099759460.9176569048371410.9711924822516960.8597163352538260.5859651968047280.9660969634736811.105442171902190.7835164433048621.029994971418071.21335803433530.9596038869185860.9052928443368221.007293342546140.8903538586021080.9716609208438630.6675193870744920.9843379483716880.5823436025246630.9993761349474340.9191421368975620.8927822583328131.001103922026870.6491643734586210.8082121896730210.6837758139840920.8356450448225881.023047707710651.181243561873951.010491371727211.007169727549151.024781753704760.9997725179373491.10063039515077
SOX10DNA mutation statusinformation
SOX10RNA expressioninformation8.077296415265880.4005379295837297.369466483650728.050229588382968.066196850249697.522699217416517.760753208062998.193771743396688.311929917427197.8919051882119308.09560800481120.042644337408493700.2387868595871160.1110313123887440.17632277264046300.05658352836636750.0703893278913980.08406426478847450.1763227726404630.11103131238874400.042644337408493700.1634987322828800.0143552929770700.014355292977070.13750352374993500.014355292977070.1890338243900170.163498732282880.02856915219677090.04264433740849370.028569152196770908.367589480412987.763477970909767.782080880768317.632486348459777.984703266825147.982822493992787.299116415794097.687410678647748.199917680274577.572586549385770.05658352836636750.09761079662642230.2868811477881610.201633861169650.056583528366367500.05658352836636750.1110313123887440.1890338243900170.1375035237499350.3219280948873620.1890338243900170.08406426478847450.2387868595871160.4005379295837290.05658352836636750.1505596765753810.05658352836636750.15055967657538100.01435529297707000.2387868595871160.02856915219677090.07038932789139800.18903382439001700.201633861169650.04264433740849370.014355292977070.111031312388744000.014355292977070.08406426478847458.338112379518827.614489006544428.529977073907337.907431504834717.976707311846880.1243281350022020.1505596765753810.1110313123887440.05658352836636750.04264433740849370.014355292977070.04264433740849370.04264433740849370.0703893278913980.05658352836636750.163498732282880.0703893278913980.04264433740849370.02856915219677090.5655971758542250.08406426478847450.1375035237499350.1763227726404630.0143552929770700.2630344058337940.137503523749935000.1890338243900170.02856915219677090.04264433740849370.1110313123887440.0703893278913980.1110313123887440.0143552929770700.0565835283663675000.2630344058337940.014355292977070.04264433740849370.014355292977070.2630344058337940.1505596765753810.02856915219677090.028569152196770900.1375035237499350.05658352836636750.1375035237499350.05658352836636750.014355292977070.05658352836636750.02856915219677090.02856915219677090.2387868595871160.02856915219677090.2141248053528470.1110313123887440.08406426478847450.1763227726404630.02856915219677090.0703893278913980.0703893278913980.1110313123887440.1763227726404630.02856915219677090.04264433740849370.1505596765753810.02856915219677090.04264433740849370.014355292977070.1243281350022020.4854268271702420.08406426478847450.04264433740849370.1110313123887440.2387868595871160.04264433740849370.1375035237499350.05658352836636750.2387868595871160.28688114778816100.1110313123887440.1110313123887440.09761079662642230.07038932789139800.1763227726404630.05658352836636750.014355292977070.02856915219677090.04264433740849370.08406426478847450.05658352836636750.1375035237499350.1890338243900170.3673710656485290.09761079662642230.1243281350022020.1763227726404638.511357340697128.345360889539640.0703893278913980.1375035237499350.2387868595871160.1505596765753810.08406426478847450.1243281350022020.02856915219677090.1110313123887440.04264433740849370.1243281350022020.1505596765753810.04264433740849370.02856915219677090.1110313123887440.05658352836636750.07038932789139800.04264433740849370.02856915219677090.2387868595871162.516015147003660.275007047499870.0703893278913988.259178313269430.04264433740849370.226508529808680.201633861169650.1375035237499350.1110313123887440.02856915219677090.1763227726404630.1763227726404630.05658352836636758.343629894959057.475571321292550.02856915219677090.02856915219677090.201633861169650.04264433740849370.1763227726404630.042644337408493700.1375035237499350.4222330006830480.09761079662642230.226508529808680.4750848829487830.1505596765753810.04264433740849370000.1763227726404630.163498732282880.1110313123887440.05658352836636750.1110313123887440.04264433740849370.310340120612150.08406426478847450.1890338243900170.4646682670034440.555816155061640.1243281350022020.1505596765753810.2986583155645150.2387868595871160.05658352836636750.0703893278913980.4750848829487830.4854268271702420.1890338243900170.1505596765753810.2387868595871160.04264433740849370.1110313123887440.2509615735332190.014355292977070.07038932789139800.04264433740849370.02856915219677090.05658352836636750.1763227726404630.09761079662642230.02856915219677090.1505596765753810.05658352836636757.8491861387434600.014355292977070.1890338243900170.04264433740849370.02856915219677090.02856915219677090.04264433740849370.09761079662642230.1375035237499350.2630344058337940.1375035237499350.08406426478847450.02856915219677090.1505596765753810.1763227726404630.08406426478847450.1763227726404630.014355292977070.0703893278913980.05658352836636750.08406426478847450.05658352836636750.1890338243900170.04264433740849370.014355292977070.226508529808680.04264433740849370.26303440583379400.2630344058337940.0703893278913980.04264433740849370.1110313123887440.0703893278913980.09761079662642230.1505596765753810.3219280948873620.09761079662642230.02856915219677090.09761079662642230.09761079662642230.1890338243900170.05658352836636750.08406426478847450.1243281350022020.1110313123887440.1110313123887440.47508488294878300.2141248053528470.0703893278913980.0703893278913980.028569152196770900.08406426478847450.1375035237499350.02856915219677090.1890338243900170.310340120612150.2141248053528470.1110313123887440.2509615735332190.0703893278913980.275007047499870.5160151470036650.1110313123887440.1890338243900170.5160151470036650.1110313123887440.1375035237499350.02856915219677090.04264433740849370.0703893278913980.0976107966264223
SOX10CRISPR gene dependencyinformation0.990.090.991.000.981.001.000.440.480.290.250.330.100.160.200.390.340.170.420.180.380.110.700.150.110.140.370.290.070.150.200.151.001.000.970.031.000.871.000.990.220.110.120.400.080.160.290.070.040.160.050.060.100.270.720.050.240.310.320.090.030.290.130.380.070.030.050.170.080.490.140.330.971.000.990.270.110.130.130.110.070.150.080.290.300.110.110.220.230.180.120.060.140.010.490.450.090.190.030.620.090.190.220.080.040.280.730.110.050.070.270.370.080.400.420.160.260.280.150.100.120.260.200.350.420.080.100.130.160.070.140.320.210.080.240.110.130.050.170.190.170.040.530.090.380.070.130.150.510.180.220.080.240.210.100.150.260.320.070.080.050.000.030.010.050.011.000.930.200.420.100.000.630.020.020.170.130.030.190.120.380.010.150.110.060.070.160.370.140.270.021.000.170.180.070.050.230.510.390.060.990.090.330.370.410.180.090.130.210.050.300.190.270.070.050.110.110.210.080.050.230.420.030.010.010.300.160.470.620.120.220.450.270.030.010.050.090.240.010.180.050.230.070.170.150.220.070.070.221.000.000.010.140.120.690.470.140.580.110.160.030.240.040.010.110.280.070.050.070.150.080.350.100.160.070.200.170.510.040.500.200.390.150.120.370.320.190.310.190.180.140.560.040.010.250.060.120.430.100.090.150.080.200.560.090.460.010.130.200.180.360.050.03

Column filtering     
     Off
  Detected in DrugMap     
     Off
  Characterized in DepMap
Lung
n = 64
Bile duct
n = 44
Skin
n = 43
Breast
n = 37
Blood
n = 30
Ovary
n = 25
Central nervous system
n = 17
Colorectal
n = 16
Pancreas
n = 12
Liver
n = 12
Kidney
n = 12
Lymphocyte
n = 12
Esophagus
n = 11
Gastric
n = 11
Uterus
n = 9
Bone
n = 9
Upper aerodigestive
n = 8
Urinary tract
n = 8
Soft tissue
n = 7
Plasma cell
n = 6
Cervix
n = 6
Prostate
n = 5
Thyroid
n = 4
Peripheral nervous system
n = 4
Brain
n = 3
Fibroblast
n = 1

Structural information

(not available for this protein)

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Using this data? Please cite Takahashi, Chong, Zhang, et al. (2024) Cell


       Bar-Peled Lab

and Lawrence Lab