DrugMap: EGFR (KB02)

name	peptide	skin_A375	skin_RPMI7951	skin_SKMEL2	skin_HMCB	skin_SKMEL3	skin_G361	skin_UACC257	skin_SKMEL30	skin_MEWO	skin_UACC62	skin_LOXIMVI	skin_WM2664	ovary_TOV21G	ovary_OVTOKO	ovary_EFO21	ovary_OVK18	ovary_OV90	ovary_PEO1	ovary_OAW28	ovary_OVCAR4	ovary_SKOV3	ovary_OVISE	ovary_NIHOVCAR3	ovary_EFO27	bile_duct_ICC21	bile_duct_ICC137	bile_duct_ICC10	bile_duct_ICC106	bile_duct_SNU245	bile_duct_ICC11	bile_duct_ICC108	bile_duct_ICC24	bile_duct_TGBC1TKB	bile_duct_ICC20	bile_duct_ICC8	bile_duct_KMCH1	ovary_OVKATE	ovary_OVCAR5	ovary_A2780	ovary_CAOV3	ovary_MCAS	ovary_OVCA429	ovary_OAW42	soft_tissue_RKN	bile_duct_ICC26	bile_duct_TFK1	bile_duct_ICC3	bile_duct_ICC18	lung_MGH0061	lung_NCIH3122	lung_MGH0651	lung_MGH0261	lung_MGH0732	lung_MGH0653	lung_MGH9153	lung_MGH0752	lung_MGH97967	lung_MGH9521R	lung_MGH92431	lung_MGH91621	skin_COLO792	skin_MELJUSO	skin_COLO679	skin_A2058	skin_SKMEL28	skin_IGR1	skin_HS944T	skin_IGR37	skin_RVH421	skin_IPC298	skin_WM793B	breast_AU565	breast_CAL148	breast_ZR751	breast_MCF7	breast_HDQP1	breast_HCC1419	breast_CAL51	breast_MDAMB231	breast_BRX68	breast_BRX390	breast_BRX250MAY	breast_BRX211MAY	skin_MEL182	skin_MEL167	skin_IGR39	fibroblast_HS839T	blood_CMK	blood_THP1	blood_U937	blood_MONOMAC1	blood_KASUMI1	blood_MOLM13	blood_P31FUJ	blood_OCIAML5	bile_duct_SNU1079	bile_duct_RBE	bile_duct_YSCCC	bile_duct_ETK1	bile_duct_ECC2	bile_duct_EGI1	bile_duct_SNU869	bile_duct_SNU1196	bile_duct_OCUG1	bile_duct_GB2	bile_duct_SNU308	bile_duct_G415	lymphocyte_HT	lymphocyte_A3KAW	lymphocyte_RL	lymphocyte_KARPAS422	lung_MGH8022	lung_MGH8021	lung_MGH8091	lung_MGH9201	lung_MGH1701	lung_MGH100151	lung_MGH1542	lung_MGH100164	bile_duct_CCSW1	bile_duct_CCLP1	bile_duct_SG231	bile_duct_HUCCT1	skin_CHL1	skin_COLO829	skin_A375S2	skin_A101D	skin_SKMEL24	skin_SH4	skin_HS936T	lung_MGH90921	plasma_cell_KMS12BM	plasma_cell_KMS11	plasma_cell_KMS27	plasma_cell_RPMI8226	ovary_TYKNU	ovary_FUOV1	lung_ABC1	lung_A549	lung_HCC15	lung_CALU6	pancreas_CFPAC1	pancreas_BXPC3	pancreas_KP4	pancreas_HUPT4	breast_HCC1937	breast_HCC1806	breast_CAMA1	breast_BT549	breast_MDAMB436	lung_MGH1543	lung_MGH1541	lung_MGH8222	lung_MGH1904	bile_duct_TKKK	bile_duct_SNU478	bile_duct_HUH28	bile_duct_ICC12	lung_NCIH1703	lung_LU65	lung_NCIH1155	liver_HLF	liver_HUH7	liver_JHH6	liver_JHH1	bile_duct_HKGZCC	bile_duct_TGBC52TKB	bile_duct_ICC9	bile_duct_MG984	bile_duct_OZ	bile_duct_SSP25	bile_duct_ICC19	bile_duct_ICC4	brain_MGG75	brain_MGG23	brain_MGG123	kidney_KMRC1	kidney_CAKI1	kidney_KMRC20	kidney_786O	colorectal_SW403	colorectal_RKO	colorectal_MDST8	colorectal_SW948	uterus_HEC1	uterus_AN3CA	uterus_MFE296	uterus_RL952	lung_NCIH2172	lung_HCC44	lung_CORL23	lung_NCIH1299	colorectal_HCT15	colorectal_LS513	colorectal_HT115	colorectal_HT29	upper_aerodigestive_DETROIT562	upper_aerodigestive_BICR22	upper_aerodigestive_CAL27	upper_aerodigestive_HSC3	ovary_OV56	ovary_IGROV1	pancreas_SW1990	pancreas_DANG	pancreas_HUPT3	pancreas_PATU8988T	prostate_LNCAPCLONEFGC	prostate_DU145	prostate_VCAP	prostate_PC3	lung_NCIH1666	lung_NCIH23	lung_SW1573	lung_NCIH1944	lung_PC14	lung_HCC827	lung_LUDLU1	lung_NCIH1975	esophagus_KYSE150	esophagus_TE11	esophagus_KYSE30	esophagus_KYSE510	bone_CAL72	bone_U2OS	bone_SAOS2	bone_SJSA1	uterus_MFE280	cervix_SISO	uterus_ISHIKAWAHERAKLIO02ER	uterus_SNGM	lung_NCIH2170	lung_NCIH2122	lung_NCIH1792	blood_MOLM16	blood_MONOMAC6	blood_JURLMK1	blood_NOMO1	blood_KASUMI2	blood_697	blood_REH	blood_JM1	skin_WM115	skin_C32	urinary_tract_KU1919	urinary_tract_HT1376	urinary_tract_UMUC3	urinary_tract_J82	urinary_tract_RT112	urinary_tract_TCCSUP	urinary_tract_HT1197	urinary_tract_T24	breast_MDAMB453	breast_DU4475	breast_CAL120	lung_NCIH1048	lung_SW1271	lung_NCIH446	lung_NCIH2286	thyroid_8505C	thyroid_8305C	thyroid_FTC133	thyroid_CAL62	breast_MDAMB157	breast_HCC1143	breast_MDAMB468	central_nervous_system_GB1	central_nervous_system_KNS81FD	central_nervous_system_LN229	central_nervous_system_T98G	liver_SNU449	liver_SNU423	liver_HUH1	liver_JHH4	liver_SKHEP1	liver_JHH7	liver_HEP3B217	liver_HEPG2	skin_COLO800	skin_SKMEL5	esophagus_KYSE180	esophagus_KYSE410	esophagus_TE4	esophagus_TE1	ovary_KURAMOCHI	ovary_OVCAR8	pancreas_PANC0403	pancreas_MIAPACA2	pancreas_SUIT2	blood_MV411	blood_KO52	blood_TF1	blood_OCIAML2	cervix_HT3	cervix_CASKI	cervix_C4II	cervix_DOTC24510	lymphocyte_SUDHL4	blood_NALM6	lymphocyte_JEKO1	blood_JVM3	skin_A431	esophagus_OE33	esophagus_TE10	lymphocyte_OCILY3	blood_MEC1	blood_HG3	lymphocyte_SUDHL6	breast_HS578T	breast_KPL1	breast_HCC1954	breast_HCC1395	colorectal_COLO678	colorectal_LS123	colorectal_SW1116	colorectal_CCK81	bone_SKNMC	bone_A673	bone_SKES1	bone_TC71	central_nervous_system_DAOY	central_nervous_system_D283MED	central_nervous_system_PFSK1	central_nervous_system_ONS76	uterus_SKN	uterus_MFE319	kidney_OSRC2	kidney_769P	kidney_RCC10RGB	lung_NCIH1793	lung_NCIH1650	lung_CALU1	lung_NCIH358	skin_WM1552C	skin_MELHO	lung_NCIH2052	lung_MSTO211H	lung_CORL88	lung_SBC5	gastric_KATOIII	gastric_MKN45	gastric_OCUM1	gastric_SNU1	peripheral_nervous_system_SKNAS	peripheral_nervous_system_KPNYN	peripheral_nervous_system_NB1	peripheral_nervous_system_KELLY	kidney_G401	soft_tissue_A204	soft_tissue_KYM1	kidney_G402	lung_NCIH196	lung_NCIH146	lung_SHP77	lung_NCIH82	gastric_HGC27	gastric_AGS	gastric_NCIN87	gastric_IM95	upper_aerodigestive_FADU	upper_aerodigestive_CAL33	upper_aerodigestive_SCC25	upper_aerodigestive_HSC4	cervix_SW756	bone_CAL78	lymphocyte_KARPAS299	gastric_MKN1	plasma_cell_OPM2	plasma_cell_SKMM2	soft_tissue_HT1080	central_nervous_system_LN18	breast_HCC1187	breast_HCC70	blood_HEL9217	blood_HEL	blood_EOL1	gastric_SNU5	gastric_NUGC3	soft_tissue_RD	soft_tissue_RH30	soft_tissue_RH41	lymphocyte_REC1	esophagus_TE8	pancreas_PANC1	kidney_KMRC3	lung_NCIH2291	lymphocyte_L428	unknown_HDMYZ	skin_MCC13	skin_MCC26	prostate_22RV1	kidney_A498	kidney_VMRCRCW	colorectal_SW837	colorectal_LS180	colorectal_SW620	colorectal_COLO320	central_nervous_system_SF295	central_nervous_system_A172	central_nervous_system_GAMG	central_nervous_system_KNS42	blood_JURKAT	blood_PF382	lymphocyte_DEL	blood_SUPT1	central_nervous_system_SW1783	central_nervous_system_42MGBA	central_nervous_system_U87MG	central_nervous_system_U118MG
	KVCQGTSNK	34	50	22	15					10	41	57	18	52	58	16	0		47	51	53			58		55	47	49	49	50	52	46	54		49	47	51	36	53		56	45	47	26	44	36		33		29	28	23	10									-19	17			42	25	27	43			35			-13	-12	58	28	55	41					1		46	51									49	44	60	47	30	42	45	55	48	30	46	28					5	26	38	56												49				24							50	24	28	31	37	52	29	31		57		42	26									52	52	28	19	15	46	26	9	21	4	16	37	30	28	46	42	47	34	53	35	47	50	27	41	48	29	48	41	41	65		48	14	36	50	48	24	39	49	51	52	56	49	23	63	51	26	49	50	58	50	58	45	42	58	22	50	57	59	45	44	44	56	28	37	35	56	47	43	52	43	14	41	49	54											50	54	54	51	50	51	37	32	25	31	62	46	47	27	42	41	59	48	50	17	27	58	55	50	42	58	51	41	48	58	39	33	56	30	8	46	54	56	73	60	42	51								50	52	54	50					48	37	47					36	28	31	53	56	57	50	50					44	5	7	49	55	56	52	16	54	20	59	-5	29	17	34	48	56	54	37	47	35	11	34	47	47	25	50					57	-2	42	23	44	47	38	49					51			48			45	49	41	49				33	50							43	43	28	42			37	48	50					54	39	47	24					47	43	42	54
	FSNNPALCNVESIQWR	30	41	-8	-8					27	39	34	24	42	31	28	-2	39	41	47	48	43	40	37	42	40	28	32	34	25	33	34	44	39	29	47	35	51	43	39	38	44	42	31	50	22	28	15	49	41	29	37	38	35	44	40	34	41	41	40	48	-14	27	-5	-1	33	18	22	31	30		30	51	38	41	19	43		47	48							47	52									53	51	54	46	41	53	45	53	47	50	46	36					50	21	38	50	49	43	30	30	36	50	47	43		10	38	45				42					43	38	49	30	43	50	48	54	35	41	38	51		47	37	29	45	34	46	36	38	35	38	52	52	45	38	12	47	29	41	40	47	42	38	42	42	39	30	37	39	55	39	53	42		35	32	22	46	41	51	15	19	42	47	23	25	38	20	35	0	35	46	47	38		51	44	28	48	45	52	40	52	53	42	56	16	41	42	43	29	48	41	54	47	35	37	25	32	40	47	38	-14	46	43	51											44	49	43	42	32	33	27	32	-8		49	35	19	-8	72	52	57	38	40	3	28	43	44	28	30	38	54	35	53	50	31	27	49	28	-16	43	52	45	49	32	-19	32	38	30	44					35	43	42	41					49	50	44							33	46	47	40	41	8					41	-8		49	54	48	53	-6	59	33	50	-8	15	34	41	48	43	53	42	43	45		34	44	34	27	46					46		43	-1		34	44	41					42	38		42			47	49	46	40				18	43	37	41	29		48	44	34	45		39	39	37	39	40	35	45	54	-7	-7	49	25	49	7					44	38	47	44
	IICAQQCSGR																																																					73	34	44																								36																	28	48	69	28																																																																																																																																																																				8		82
	DEATCK									12	31	32	12									54	35	38	45					31	34	35	42		21	26	32	21	41	14	39					2		4										24	35	12	18														0				31																		22	25	46	45	30	36	32	45	24	38	24	25									21	42	1	23	31	32	34	44																			30	40	26	27	15	22								34	26	-4	27				31	62	50	34	25	27	32	17																																																		16		38	18					39	38	28	30																		29	22	24	44								51	63	16	46			43																					24	32	35																																									16	44	-35	23	28	41																																			33	34													39		35			37	39		42	41
	DTCPPLMLYNPTTYQMDVNPEGK		5																															18	-4	5	2					25	1	14	22					37	22	18	35									3	24																	7																	-1	20	35	24																																																30																																																		20	18	25	15															1	6	8	9	34	10	35	37																						39	19	29	14	30	14	24	20	-8	40	25					34	34	9	21	18	12	27																																				23	14	20							19																																																													21	15																			23	20													20	-3	-7	-23
	YSFGATCVK		43							40	39	56	26	47	45	35	26	36	42	43	42	17	33	47	41	48	42	41	32	50	37	34	42	43	40	36	46	39	57	33	45	45	34	35	44	27	51	32	45	38	43	59	33	66	58	54	53	56	59	47	37	23	35												31		61	37	42	30																	43	48	68	52	32	44	51	58	49	43	48	36					41	33	35	37	41	39	23	23	34	41	51	45								40							57	28	43	44		32	14	1	15	48								32	33	27	36	39	44	27	25	48	54	8	32	8	34	32	36	44	32	43	40	2	45	53	34	53	44					48	30	38	61	49	49	38	38	49	50	29	41	44	38	51	47			45	17	19	38	22	46	42	15					26	52	50	52	55	35	55	48																						43	43	46	45	39	45	24	45								46	52	38	48	12	21	52	34	37	40	48	50	35	42	47							49	54	41	46										40	47	48	38					41	33	43							30		44	13	39	6																				46	36	47	23	59	-9	-3	15													23	27	34	45	53	57	47	46								43	43	55				47	43					55				17	41				51	52													38	24	38	41
	NYVVTDHGSCVR																													32	35	33	34	47	20	40	42	21	37	15	30	32	45	21	35						44	35	15																																												27	42	53	40					27	4	21	0																																																																																																																23	5	30	30
	ACGADSYEMEEDGVR		21																			15	8	36	20	30	28	28	21	26	20	20	36	37	26	22	36	20	40	0	29	31	4	36	35	10		13		3	13	31	16									25	28																	8																	29	31	47	39	19	15	35	44	37	32	37	12									34	8	13	18	21	3	36	34								18							36	9	26	13										18	6	46	26	28	29	-1	11	40	52	26	19	5	52	-18	22	7	24	13								40																																		17	30	43	36	29	31	38	31	35	18	50	43																						36	27	38	39	18	37	19	34								18	47	21	15	8	21	51					27	21	24	31							36	44	42	29										10	29	34	16					27	26	28							27		36	8	18	17											51	22	31	21	49	23	23																																							38	35										51				29	26				44	32					43	24	19	1
	KCEGPCR																																																																																																12	28	49	49
	KVCNGIGIGEFK	30	42	21	36					25			39	34	40	24	15	28	39	33	54	29	27	38	39	44	33	36	37	34	40	38	45	38	37	40	45	43	47	22	51	42	37	38	45	36	42	32	48	35	34	40	41	39	39	36	37	43	44	40	37	23	39			36	23	26	37				45	36	41	17	51	45	53	50																	40	36	48	34	35	54	40	49	38	36	37	34					25	4	42	42	44	34	24	26	31	42	42	49								33					26	43	46	39	37	48	30	59	41	38	39	56	26	47	42	14	36	29	41	47	41	27	42	43	54	28	40	13	52	33	40	38	44	41	44	46	37	50	40	48	42	42	46	60	37	14	43	44	38	40	41	61	45		45							28	43	56	51	49	11	50	45	30	51	51	41	43	46	54	51	55	46	44	55	54	39	49	38	60	35					47	50	45	19	40	40	52											56	48	48	42					24	33	53					56	58	31	49	26	35	51	28	42	37	49	57	46	61	54							51	43	41	41	54	49	48	38	55					49	51	53	49					50	43	47							55		51	42	47	24					24	8	-2	49	53	50	55	24	50	47	53	2	20	35	48	47	41	47	33																	26	43	31	41											47	46	43	43				53	48					59	54	42	41	40	45	43	45	39	41	35	41	53	17	-6	49	41	47	28					50	28	41	43
	NLCYANTINWK	45	45	6	23					40	40	64	25	57	55	34	15	40	47	48	56	33	46	58	55	45	37	39	39	59	49	37	53	57	48	39	55	50	64	32	53	50	35	40	54	32	49	25	63	64	70	64	53	67	54	57	58	62	64	58	44	15	36														61	40	59	61																	51	47	68	48	36	50	53	66	56	50	61	37					24	34	48	43	60	35	34	16	30	52	58	55															63	31	48	43	25	37	38	44		56								45	38	34	41	50	60	31	32	30	60	35	41	33	45	48	50	45	36	54	60	33	61	53	32	58	51					44	34	39	59									45	48	60	51			59	44	47	52									49	60	64	59	58	46	65	53					44	43	40	22														53	48	61	61	41	35	43	35	23	53	57					47	58	42	42	7	15	58	39	36	39	48	54	40	46	52							60	52	47	36										52	54	53	45					53	43	48							49										47	20	17	51	41	48	50	25	54	51	58	25	20																							37	36	50	58	53	50	42	48								36	60	69				59	59					57		42	45	13	43	52	47		61	59
	CNLLEGEPR		24																							31	29	23	26		30	21	22	30	25	30	26	16	31	23	24	34	34	24	31	28	35	26	23	8	-1	28	5	25	21	19	30	35	28	25	17	12	17										47	38	25	20				-4																	48	28	42	41					52	19	37	20					43	13	28	32	30	11	-13	27	0	36	27	29								17							24	12	19	31	24	35	6	29		34								23	35	17	24	31	42	21					12	32	19	33	12	35	14	31	28	4	27	33	36	37	34	40	22	37	24						19																									25	30	34	30	36	39	38	42										46	36											32	23	28	22					25		26					42	52	34	24	11	19	41					32	25	46	35							37	37	42	23										24	35	41	31					31	37	39							22																41	19	50	10	42	6	-3																																							37	32										47
CYS 775	EILDEAYVMASVDNPHVCR		24							30			45	13	12	20	20	12	18	11	7	27	5	17	6	11	10	19	13	19	11	18	9	17	11	27	17	14	12	23	13	17	12	26	15	26	8	25	5	19	16	27	8									16	20												15	19	8	15	20	4					27	39	9	13									22	16	13	5	22	28	26	26	18	28	17	23					23	20	29	19	32	35	27	22	30	20	18	10	-12	14	4	-3				1							18	19	19	14	17	19	17	16	28	23	0	17	15	36	19	-5	24	26	17	29	14	18	15	15	18	25	14	13	24	16	16	24	21	23	24	31				13	8	1	3					16	13	25	1									20	21	12	22	23	28	13	23	30	19	16	17	19	16	19	26	7	36	9	7	4	8	15	22	18	19					19	14	29	15														8	14	-13	10												13	7	16	30	9	18	9	-5	31	10	13	17	21	22	12	36	18	27	29			10	17	25	28	26	18	7	21	17					13	12	11	21					21	17	17					23	10	25	14	11	22	6	11					18	27	12	5	13	11	13	13	20	35	7	22	20	21	20	9	21	13	19	11	5	17	19	2	18	35	11					16	14	19	-23					15	9	16	14	17			21			11	13	13	17				0	17	11	11	10		0	10	18	17	20	8	19	9		3	20	11	21	23	44	14	7	12	22					24	6	14	11
CYS 818	DNIGSQYLLNWCVQIAK																				8	13	15	12	19	13	7	14	30		15	31	13	11	5	15	-10		6			14	13	8	16																																																				8								3		3																																12	11	10	4														26	18	33	13																			13	5	14	15																	4	10	19	3	19	17													22	22	21	15	5	10	11	16																																																																																								13																7	11	5							0	10	3	14																									7			15			14	8	5	17										13	7	14													18	10	16	-1
CYS 818 *	CVQIAK	37	46	55	54					53	55	48	55					51	48	40	43	53	51	42	48	53	46	44	38	51	46	57	48	47	54	50	45	53	48	48	43	51	46	52	51	37	50	46	53	52	49	40	39	45	41	52	44	50	50	39	52	51	36	41	52	50	41	50	45	50	41	50								36	41	41	40	45	45	38	44	49																									39	30	46	51	54	51	50	55	41	46	49	50	38	38	39	39											40	48	41	46														45	31	56	48	32	35	33																37	42	38	41	36	44	50	41	36	33			32	36	14	29											39	40	44	35													33	30	30	34									22	30	41															43	37	49	32												38	25	27					40	27	32	31	26	37	39	30	38	46	36	46	33	35	39	45																30	32	37					43	38	36	34	42	47	39	47									38	41																																																			47	45											44	45
CYS 939 *	LPQPPICTIDVYMIMVK		17							9			38	25	23	28	10	14	25	25	23	38	21	22	19	26	26	25	26	9	25	25	23	17	21	29	27	30	21	7	24	24	28	24	27	29	17	22	23	23	23	23	25	22	18	26	14					17	8										41	27	34	22	28	17	21	19	42	36	38	40	33	28	25	20									19	25	25	16	26	33	24	26	20	18	22	22									35	17	43	43	22	19	19	27								20							23	24	18	24	13	21	23	15		23								29	22	14	22	26	34	10					23	12	19	21	30	10	-1	26				20	1	20	26					19	28	24	20		23							17	6	26	4	20	35	19	18	11	18	22	16	14	-2					25	34	22	28	21	19	25	13									40	21	15																			27	19	16					16	21	13	20	19	20	20					15	18	19	19							23	31	35	14	21	36	15	22	27					8	19	19	18					24	30	15					9	15	43	14	28	25	24	31					21	17	32	16			22	10	11					12	19	13	17	13	14																	17	20	45	21					16			17				8	20	18				19	23					19	12	22	17	21	22	23	23	24	-5	-2					24	7	11	22					15	22	14	8
CYS 950 *	CWMIDADSRPK		24							20	34	35	53	27	26	19	12	23	21	21	25	17	26	24	29	24	27	27	28	36	28	28	27	28	28	32	29	23	20	24	27	26	32	35	30	25	31	28	28	24	23	25	14	28	16	21	27	26	22	21	19	21	25										29	22	24	22	28	26	20	23					26	25	24	21									21	15	21	24	19	15	20	19	21	25	26	26					40	30	38	42	40	36	40	46	19	29	31	35				14				15	13	17	-7	19	24	29	17	16	20	23	19	27	21	24	4	24		24	18	26	44	23	31	28	30	28	32	20	31	21	12	32	30	29	24	11	31	22	23	18	27	33	28	32	31	25	16	23	28	16	16	34	2	24	26	49	33	19	17	24	21					18	17	24	19	22	21	24	25	9	14	21	21	26	9	28	16	29	27	38	38	32	31	25	24	26	20					11	14	4	-6														23	19	24	16	29	28	43	33	2	24	21	7	19	2	25	29	30	33	26	28	20	23	10	28	26	24	19	12	18	22	14	31	22	25	22	23	25	27	26	26	24	26	5	16	10					22	26	22	17					25	18	25					13	8	13	16	27	24	28	20					27	23	14	26	26	29	23	27	26	14	30	12	26	16	19	17	29	18	17	27	9	25	21	17	21	31	28					17	30	21	23	32	23	34	30	29	34	37	29	14			28			27	26	17	30				34	30					32	17	35	24	-1	25	19	24		21	23	18	22	15	2	22	22	31	12					7	25	31	26
CYS 1049	TPLLSSLSATSNNSTVACIDR		27											21	15	11	17	8	15	11	14	27	20	19	23	26	22	22	28	20	17	24	23	10	14	23	25	28	13	10	7	21	24	13	23	18	13	25	19	28	2	9	24					11	5	5	8	16	16												36				19	20																	33	29	30	21					35	35	27	16					40	41	29	16	30	29	27	25	23	16	18	28								14							28	21	23	18			39		17	27								15	21	43	11	19	40	11	19	19	39	18	31	19	21	38	24	33	20	49				31	30	34	22					22	14											21	31	27	26			20	18	11	15	19	29	19	21					27	19	18	14	26	29	35	24					27	31	28	27														25	24	23	27	28	25	20	38	4	29	27					22	32	29	14	19	25	27					23	27	30	30							29	18	20	27			27	29	34					18	24	23	27					27	25	23							31		28	31	21	23					20	27	17	24	43	22	37	17	30	30	39	7	21			30	21	24	26																	23	29	22	13					14			21				25	30	18				16	21					25	24	20				20	19		27	21													24	34	25	20
CYS 1058	NGLQSCPIK		22															28	24	31	40	25	30	41	44	35	26	39	35	39	37	43	45	39	35	34	43	30	41		33	38	25	23	44	30		33		30	28	33	28					49	45	42	37	17	16												38		49	19	32	44																	35	40	51	38	36	36	27	45	47	31	42	33					19	27	40	36	50	19	19	29	20	27	41	48								31							48	26	38	37	37	45	30	46	21	36								39	42	36	32	40	68	29	26	26	52	30					34	30	25	45				33	36	52	42	33	32	45	31	42	27	47	50	38	35	38	20					36	35	32	32			38	30	28	36													44	32	51	50																						37	43	44	48								32	33	38	32	40	46	32	32	31	26	39															36	37	41	27																		32	38	31																	16	25	19	29	58	35	44	30	37							35	29	30	22																					13	7	-6	0																							34	26	37				47	42

EGFR	DNA copy number	1.13214108944071	1.37498330624223	1.24572085783884	1.24224395966337	1.68444004061865	1.59963421783799	1.17388484147859	0.874920296105918	0.988816187501611	1.27098399819888	1.01175802712821	1.4538099444745	0.984270692210935	0.975962646098449	1.10746714674445	1.03312271261213	1.1186822667286	1.06785008837962		1.3249833476519	0.646214728123304	1.27395233560188	1.03269886406905	1.08483062560747		1.1363800308231	1.03601767099829	1.18547582196931	1.17039500995853		1.13837406659744		1.13844228403266		1.33741354129278	1.34614009631025	1.03205743806574	1.32399698231109	1.03885965356006	1.30376001373616	0.903342897293527		1.1401442221705	1.34841804456683		1.02807853170218	1.2177298021841														0.916269762161808	1.51844034105499	1.30965622200778	1.2424798166596	1.02799699196884	0.98672563685263	1.06765555525935	1.24515651476054	0.937342648868863	1.06933340507899		1.65803696767012	1.3120164150165	1.08932902973738	0.894771678081665	1.49545802447857	1.21737241972169	1.0243765219868	1.13161970087697							1.19730781517682	1.00588897031684	0.847937394705937	1.00309130483451	1.12781331205935	0.987816384030014	1.01176508396365	0.968431623494522	1.23480101649662	0.98457782180227	1.62613747165809	1.06616910900278	3.67085335550115		1.18306186729702	0.753113357912793	1.04635251113944	1.06860596151054	1.38058953897153	1.10814840456332	1.18320064943176	1.03994204933279	1.0058081446376	1.03812377666003	1.29869014552301	0.984533306127092									1.1954405112586	1.01265855189498	0.823854054388994	1.28392899923897		1.25066108845455		1.4430802324478	1.02921545334302	0.958576317668148	1.18856241217064		1.4265727611964	1.24658850228503	0.995541410905578	1.21288092436168	1.41408106823655	0.812037513999711	1.49547029452661	1.11552599125312	1.16284335703923	0.850486294669871	0.89724951976598	1.15879011203618	1.27007584035348	0.959049699629263	1.28473417292692	0.963539203659212	1.11906264697067	1.16831914940265	1.15543864386256					1.84819651729354	1.26703662968055	0.885191261120428	1.11119736960365	1.47949304338984	1.67509744063324	0.986897048090632	1.09265724268325	1.25399044143443	1.17981971128085	1.29977713329763	0.971277240265016	1.06132125827399	1.29816970603445			1.24382493384887		1.26652266420779				1.12715714464805	1.17447456081733	1.01136138678026	1.08889712070188	0.945486021650816	1.02351151476622	1.37171495406896	1.34246618736259	1.12175148519376	1.30720269562121	1.04257885304567	1.03476964133785	1.08994662031966	1.31308694115295	1.03313549638331	0.93013180803371	0.998881933578161	1.27855663713967	1.37489621108669	1.23910000066975	1.12936199718175	1.02217382661782	1.83206147214113	1.71605046175682	0.88474376485063	1.11553568386958	1.26563492834005	1.57317869475917	1.04123134969887	0.961309145476694	1.0189690896361		1.16963941578844	1.29892637371904	1.11138160172144	1.32075811092868	1.11003228937001	0.970516563480336	1.80482645577723	4.87105628311712	1.92790178298606	1.58877529165723	1.3782889231592	1.76613804184907	2.87242510842576	0.85453269031572	0.60227075543016	1.30363746151768	0.926676534021907	1.01145411137857	1.25605943081763	1.1386098374483	1.03818688184649	0.982141912961883	1.22620504896882	1.28358224183162	1.6902608245943	1.15532678011902	1.04711919478455	1.00591106010385	0.998733556350701	0.600180932348743	0.992863737465231	1.00004850081523	0.940374458147165	1.58738351527405	0.990385253495311	0.754181871658662	1.17638424956771	1.02843735921052	0.922548061680918	1.03624259978459	1.20035033972704	0.949603684256136	0.95665583514226	1.05514991093918	1.21748811996981	1.07018582850024	1.09072145781975	1.02533206872573	1.17394608762845	1.08242697247394	0.989258289333001	1.52539349147004	1.30839362964736	1.03634918361876	1.36225617543244	1.4488261517161	4.72970131952453	1.62661141054242		1.53923598862816	1.19559406383536	1.18684911966372	1.13217915319333	1.06750496540728	1.64657818465225	1.3116401853701	0.980327976254982	1.45517735103448	0.958507872976138	1.42408971438124	1.42762298079611	1.98459325697518	1.16050358808926	2.04818420276846	1.72046154537756	0.931350762405542	0.948541761830692	1.08070842688267	1.20270263932001	1.12478890637203	0.9854545718296	0.993713755462081	0.902548790038864	0.983034936634405	1.00725113136815	1.29797348612159	1.04066081931771	1.2077579935055	1.26917932212179	0.98968662909803	1.11269437201635	0.998562716660001	2.46576579187809	1.33059225816469	0.835794101933556	1.00400002993162	1.20627401599641	1.03329146710786	1.30344115477616	1.12896193974014	0.906175434670948	1.20720745934413	1.05565266363002	1.1762041727514	1.25929530825758	1.31082226363693	1.08986443810086	1.0001770108578	0.902238168981873	1.21593672373524	0.879290752735597	1.83050127456695	0.600863604389119	1.07160528092201	1.13837788670284	1.09125679344545	1.04781294446491	1.22590848582056	1.04875031249068	1.13923817049139	1.21319993219468	1.50668543175063	1.25611291241995	0.94235667801913		1.10973712145262	0.814501020522694	1.097427648038	1.00324263594242	1.06591471364121	1.50038199574831	1.58263144334729	1.34066873031546	1.00680849017273	1.41204336994659	1.02492668761681	1.09366983865764	1.26645573215289	0.996421449268709	1.03396462716444	1.04039413101106	1.01651900251234	1.22128388422674	1.05592667775521	1.38178168628533	1.09167446662884	1.04812895194596	1.04721363784726	1.04574397677306	1.38396919201514	1.44128032714227	1.56420720604353	1.16702228891946	1.45791237983425	1.13617563024623	0.847965838034174	1.02499737978761	1.27572132064029	1.21732682548801	1.03625950921976	1.00386917450942	1.30477699453978	1.47390430939634	1.68936491856674	0.824459400534833	0.82544057795804	0.971918237411496	1.65192487743215	1.42685348729808	1.28581982527492	1.13899467124737	1.08206496546822	0.995570321435116	3.3964595834401	1.32520146577464	1.01439460278888	1.40534924266278	0.962756005728244	0.900489805532847	0.994293331375472	1.17314225746997	1.27600367812976	1.45764157610389	1.28167076250546	1.04150435453633	1.04289018208103	1.41624242964539	0.88693604241673	1.59039560309584	1.64043712721341	1.4926819863469	1.16206493701859	0.997813659166362	0.998995350047962	1.16443776897439	1.14891171897134	1.28338512424257	1.21215553719339	1.04819711892221	1.2831211931026
EGFR	DNA mutation status	0	0	0		1	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0		0	0	0	0		0		1		0	0	0	0	0	0	0		0	0		0	0														0	0	1	0	1	0	0	1	0	0		0	0	0	0	0	0	0	0							1	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0									0	0	0	0		0		0	0	0	0		0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0					0	0	0	0	0	0	1	0	0	0	0	0	0	0			0		0				0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	1	1	0	1	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	1	0	0	0	1	0	0	0	0	0	1	0	0	0	1	1	0	1		0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	2	0	0	0	0	1	0	1	1	0	0	0	0	1	0	0	1	0	0	0	0
EGFR	RNA expression	1.4905701304462	4.34340782229781	0.0565835283663675	0	2.63459326844576	0.0976107966264223	0.189033824390017	0.176322772640463	1.43295940727611	2.20789285164133	4.50842865253186	0.75702324650746	4.16108148227718	4.8703647195834	5.69682846458871	0.367371065648529	1.35049724708413	3.3533232911629		4.16188768237689	5.50493813164961	5.60821785302146	4.3037807481771	5.31324585178756		4.03298241669943	5.96624587322494	5.44824022521607	3.88752527074159		5.61087719947195		5.18269229751619		4.96069703930431	7.41125674622079	5.9902741833186	6.13975597548131	1.4541758931858	5.37851162325373	5.64270157183323		4.66845955691538	6.32750773458721		4.2637856138908	1.58014548442338														0.150559676575381	0.970853654340484	0.124328135002202	0.16349873228288	0.495695162624069	0.344828496997441	2.58255600301406	1.55090066464752	0.124328135002202	0.070389327891398		4.99909803370561	2.90303827011291	1.96716860753263	0.263034405833794	4.44028782084042	0.0840642647884745	3.67919857056692	5.72683121703249							4.39780296186249	5.07809742302666	0.137503523749935	0.176322772640463	0.070389327891398	0.150559676575381	0.286881147788161	0.070389327891398	0.263034405833794	0.238786859587116	5.93522399406003	4.10349763970334	9.25802418543952		4.8972404255748	3.33913738491959	3.64385618977473	5.55887985347544	4.81352468929781	5.55397480823747	5.89602960297675	5.86690797814317	0.124328135002202	0.150559676575381	0.20163386116965	0.150559676575381									4.58496250072116	4.61470984411521	4.34127418369217	5.97269265400426		0.238786859587116		2.93734439215023	2.10097764772482	0.16349873228288	1		0.137503523749935	0.0976107966264223	0.070389327891398	0.333423733725192	3.45811948117451	4.31976242766925	6.50827017556779	5.34589308568741	4.99367436175059	4.35825558670513	5.17032569441556	5.9706236144706	3.47767732756531	4.32984117653063	4.98732086592925	5.30669970727279	0.0976107966264223	5.52136487844622	4.71808758396052					7.06856333533888	5.50112063427539	3.611172380044	5.62410089462811	5.46139758992616	6.24792751344359	2.74631276642546	5.9469647411558	5.47378691161437	5.94649694120329	5.10810622368613	6.10307794659757	4.62819033461521	5.01256867350306			5.18388345903223		5.65477921695952				4.26453643099903	4.16430358309365	6.39574832817903	5.33842441478356	2.13093086982645	1.33342373372519	5.54751152364422	3.89627184880738	3.02856915219677	4.58676474335514	1.49569516262407	6.28188367456292	4.57893871309339	5.39437694495706	4.85598969730848	3.4867143730307	3.92409988564074	3.74631276642546	3.48928602262588	3.44493204894218	5.99909803370561	4.93734439215023	8.08719761557795	7.69146437341683	4.98823022306046	4.49121175600309	4.41683974191283	5.07937811111865	5.39780296186249	6.15987133677839	4.45022149589718		2.17312743348066	4.82883464946806	5.47021145739054	3.80322703643493	5.42021289061078	3.09929520433778	6.56757586852411	9.67364475243824	6.30268461411838	5.32373033752135	6.80309784950483	6.13996056954546	8.35952995532291	4.30669970727279	3.48026512205446	2.16349873228288	3.08746284125034	4.06695024392463	2.63226821549951	5.70182625841205	3.72574115650395	5.09043004232162	1.50589092972996	3.59454854955035	5.79181407116183	0.137503523749935	0.124328135002202	0.189033824390017	0.137503523749935	0.150559676575381	0.137503523749935	0.124328135002202	0.137503523749935	1.83995958748953	0.799087306074004	5.62585493136806	7.04494049127973	5.35614381022528	4.78764141448333	5.6564963705535	4.85449441815488	5.9143253300853	5.10475598696226	0.150559676575381	0.214124805352847	5.35085080548338	5.50652577904312	5.17472598770613	0.0565835283663675	5.15340002773506	5.9979697822671	6.58345891013077	5.18269229751619	5.59006301881225	3.55704241526372	6.31795521831244	9.18256816161399	3.94579495674006		4.42223300068305	5.33556900555675	5.36946648365072	5.21529030565123	3.93734439215023	5.88386515450979	5.66931028620247	3.80426011563474	5.48446041312882	1.83187724119167	0.632268215499513	0.545968369105293	7.20084957463721	5.07081863753328	5.30997649237056	6.20554891117303	2.07724299893246	4.86393845042397	4.43028527297778	3.88264304936184	5.39231742277876	0.0840642647884745	0.111031312388744	0.214124805352847	0.137503523749935	4.11270013274936	5.48574882137778	5.4757334309664	5.9797967182782	0.422233000683048	0.124328135002202	0.150559676575381	0.124328135002202	7.6442889333787	5.32373033752135	4.63343121035563	0.16349873228288	0.070389327891398	0	0.37851162325373	4.90785207184596	1.14404636961671	5.12969515665378	4.70321146739115	5.77214959078454	4.603477988254	4.47638168756724	2.72465027173297	0.176322772640463	0.31034012061215	0.263034405833794	0.111031312388744	5.29975751183932	0.495695162624069	0.286881147788161	5.32840565895857	3.72246602447109	4.78711898281334	6.97911075501579	5.27500704749987	7.43162295971329	4.84096670448742	6.07831095000713	6.47654370621426	3.97636363573276		0.111031312388744	5.5963388642052	5.37989816352469	1.22650852980868	0.704871964456353	4.74038793246835	4.63923216324928	5.74416109557041	6.14139191617073	5.54565954002547	2.72900887033786	3.1811025507538	2.85798099512757	0.298658315564515	0.622930350920177	0.0840642647884745	0.176322772640463	5.10433665981474	0.111031312388744	2.49825086752783	0.0976107966264223	0.150559676575381	3.80219321694182	5.10726939359254	4.26077843189343	6.55366768848306	7.47986108501682	5.17592374206376	7.69285956238577	5.69181329717138	3.82883464946806	0.124328135002202	5.25323293853803	0.150559676575381	0.124328135002202	4.29572302453997	4.77873424411784	5.13873256972024	6.34216358328935	0.0976107966264223	0.0976107966264223	0.124328135002202	5.53760669149529	5.4541758931858	4.66505161428921	3.03738222200308	0.20163386116965	2.28688114778816	7.88758619407687	5.85024935828633	6.92041240816079	6.10349763970334	0.0976107966264223	4.35543919724869	4.28466218548316	3.93922657772821	2.8073549220576	5.44028782084042	6.3743439890385	4.16188768237689	3.89917563048051	0.0976107966264223	0.176322772640463	4.88215391728701	5.04745114041639	6.68355610749568	3.62527048937469	0.0976107966264223	0.22650852980868	0.20163386116965	0.286881147788161	4.98686597232911	4.85648777949568	5.10894256866079	5.57288966842058
EGFR	CRISPR gene dependency	0.04	0.18	0.03				0.02	0.03		0.06		0.03	0.07	0.75	0.02	0.02	0.08	0.31			0.05	0.33	0.02	1.00		0.08	0.84	0.79			1.00		0.97		0.06	0.99		0.62	0.03	0.08	0.87		0.03	0.07		0.66	0.17														0.09	0.00	0.10	0.08		0.01	0.03		0.10	0.18		0.04		0.30	0.14		0.04	0.04	0.03							0.09			0.07	0.09	0.02	0.04	0.05	0.05		0.06	0.71	0.31		0.75	0.42	0.15	0.57	0.26	0.97	0.16	0.14	0.09	0.01	0.02	0.03									0.34	0.04	0.05	0.97					0.22	0.04	0.14			0.01	0.08	0.05	0.00		0.10	0.19	0.03	0.19	0.15	0.03	0.02	0.96	0.33	0.31	0.02	0.03	0.08					0.65	0.98		0.09	0.02	0.26	0.04	0.02	0.02	0.09	0.99	0.95	0.81	0.80			0.60		0.94				0.20	0.84	0.52	0.19	0.02	0.03	0.05	0.10	0.09		0.01	0.58	0.21	0.11	0.07	0.07	0.02	0.51	0.90	0.57	0.81	0.84	0.81	0.79		0.11	0.26	0.06	0.83	0.31	0.03		0.07	0.10	1.00	0.02	0.03	0.11	0.99	0.06	0.87	1.00	0.24	0.48	0.85	0.13	0.01	0.11	0.08	0.06	0.03	0.78	0.08	0.22	0.06	0.03	0.75			0.03	0.01		0.04	0.04	0.03	0.04	0.01	0.07	0.97	0.16	0.03	0.03	0.12	0.04	0.01	0.01	0.07	0.05	0.02	0.03	0.03	0.12	0.06	0.02	0.16	0.05	0.04	0.17	0.06	0.05		0.29	0.06	0.28	0.02	0.50	0.10	0.04	0.05		0.02	0.05		0.25	0.19	0.03	0.22	0.27	0.13	0.94	0.06	0.54	0.02		0.09	0.01	0.03	0.44	0.90	0.88	0.01	0.11		0.02	0.95	0.52	0.71		0.17	0.04		0.01	0.02	0.67	0.05	0.53	0.24	0.86	0.17	0.06	0.08		0.01	0.05	0.03	0.10	0.02	0.02	0.57	0.15	0.91	0.40	0.24	0.07	0.14	0.41		0.11	0.22	0.03			0.13	0.02	0.11	0.06	0.03	0.01	0.06	0.05			0.03	0.06			0.03	0.18	0.03	0.11	0.44	0.88	0.06	0.89	0.61	0.99	0.17	0.10	0.20		0.02	0.09	0.06	0.05	0.01	0.02	0.03	0.03	0.06	0.10	1.00	0.02	0.23			0.94	0.07	0.25	0.15	0.15	0.05	0.04	0.02	0.02		0.02	0.51	0.54	0.02	0.03	0.05	0.07	0.07	0.03	0.03	0.07	0.03	0.05		0.03	0.06	0.03

Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
EGFR	P00533	7syd	2.4	13.3	19.0	11.0	30.0	0.1	-1.9	-3.5	-0.2	-0.4	-0.9	27.5	-124.1	-135.1	160.8	E	0.0	0.0	0.1	0.1	0.1	0.6	0.0
EGFR	P00533	7syd	1.9	19.9	11.0	25.0	36.0	0.1	-1.0	-0.3	-0.2	-0.1	-0.9	45.2	40.8	-143.3	164.8	N/A	0.3	0.0	0.3	0.0	0.0	0.5	0.0
EGFR	P00533	7syd	2.0	27.5	18.0	5.0	23.0	0.1	-0.3	-0.1	-0.2	-0.1	-0.4	73.1	-95.1	-105.3	168.2	S	0.2	0.0	0.0	0.2	0.2	0.4	0.0
EGFR	P00533	7syd	2.3	8.4	17.0	14.0	31.0	0.0	-1.5	-0.2	-0.3	-0.2	-0.8	39.3	-173.8	-89.3	115.9	N/A	0.2	0.2	0.4	0.2	0.0	0.0	0.0
EGFR	P00533	7syd	2.0	17.6	25.0	12.0	37.0	0.1	-0.3	-0.1	-0.1	-0.1	-0.3	55.1	-90.4	-66.7	147.0	P	0.0	0.0	0.3	0.3	0.3	0.0	0.0
EGFR	P00533	7syd	2.7	12.9	19.0	14.0	33.0	0.1	-1.5	-0.3	-0.3	-0.2	-0.9	33.6	-173.7	-100.1	120.4	E	0.2	0.0	0.5	0.2	0.0	0.2	0.0
EGFR	P00533	7syd	5.1	0.0	20.0	20.0	40.0	0.1	-3.0	-0.4	-0.4	-0.2	-0.7	40.3	178.3	-78.7	109.5	E	0.0	0.0	0.3	0.2	0.0	0.2	0.3
EGFR	P00533	7syd	1.8	38.2	19.0	13.0	32.0	0.2	-0.2	-0.1	-0.2	-0.1	-0.2	43.2	-60.1	-79.6	171.8	N/A	0.0	0.0	0.3	0.0	0.3	0.3	0.0
EGFR	P00533	7syd	1.9	35.1	11.0	6.0	17.0	0.2	-2.8	-0.7	-0.1	-0.1	-0.4	20.3	-141.7	-69.0	145.7	P	0.1	0.3	0.1	0.1	0.1	0.0	0.1
EGFR	P00533	7syd	2.3	15.0	22.0	13.0	35.0	0.1	-1.4	-2.5	-0.5	-0.1	-0.5	16.6	-110.7	-86.4	145.7	E	0.0	0.0	0.5	0.2	0.0	0.3	0.0
EGFR	P00533	7syd	2.4	6.2	15.0	27.0	42.0	0.0	-1.7	-0.4	-0.4	-0.1	-0.4	60.2	39.3	-94.7	176.7	N/A	0.3	0.0	0.0	0.0	0.0	0.3	0.3
EGFR	P00533	7syd	2.4	5.5	16.0	13.0	29.0	0.0	-0.3	-0.9	-0.1	-0.1	-0.2	54.6	-111.1	-93.2	52.9	N/A	0.2	0.2	0.2	0.2	0.0	0.2	0.0