DrugMap: EGFR (KB03)

name	peptide	skin_A375	skin_RPMI7951	skin_SKMEL2	skin_HMCB	skin_SKMEL3	skin_G361	skin_UACC257	skin_SKMEL30	skin_MEWO	skin_UACC62	skin_LOXIMVI	skin_WM2664	ovary_TOV21G	ovary_OVTOKO	ovary_EFO21	ovary_OVK18	ovary_OV90	ovary_PEO1	ovary_OAW28	ovary_OVCAR4	ovary_SKOV3	ovary_OVISE	ovary_NIHOVCAR3	ovary_EFO27	bile_duct_ICC21	bile_duct_ICC137	bile_duct_ICC10	bile_duct_ICC106	bile_duct_SNU245	bile_duct_ICC11	bile_duct_ICC108	bile_duct_ICC24	bile_duct_TGBC1TKB	bile_duct_ICC20	bile_duct_ICC8	bile_duct_KMCH1	ovary_OVKATE	ovary_OVCAR5	ovary_A2780	ovary_CAOV3	ovary_MCAS	ovary_OVCA429	ovary_OAW42	soft_tissue_RKN	bile_duct_ICC26	bile_duct_TFK1	bile_duct_ICC3	bile_duct_ICC18	lung_MGH0061	lung_NCIH3122	lung_MGH0651	lung_MGH0261	lung_MGH0732	lung_MGH0653	lung_MGH9153	lung_MGH0752	lung_MGH97967	lung_MGH9521R	lung_MGH92431	lung_MGH91621	skin_COLO792	skin_MELJUSO	skin_COLO679	skin_A2058	skin_SKMEL28	skin_IGR1	skin_HS944T	skin_IGR37	skin_RVH421	skin_IPC298	skin_WM793B	breast_AU565	breast_CAL148	breast_ZR751	breast_MCF7	breast_HDQP1	breast_HCC1419	breast_CAL51	breast_MDAMB231	breast_BRX68	breast_BRX390	breast_BRX250MAY	breast_BRX211MAY	skin_MEL182	skin_MEL167	skin_IGR39	fibroblast_HS839T	blood_CMK	blood_THP1	blood_U937	blood_MONOMAC1	blood_KASUMI1	blood_MOLM13	blood_P31FUJ	blood_OCIAML5	bile_duct_SNU1079	bile_duct_RBE	bile_duct_YSCCC	bile_duct_ETK1	bile_duct_ECC2	bile_duct_EGI1	bile_duct_SNU869	bile_duct_SNU1196	bile_duct_OCUG1	bile_duct_GB2	bile_duct_SNU308	bile_duct_G415	lymphocyte_HT	lymphocyte_A3KAW	lymphocyte_RL	lymphocyte_KARPAS422	lung_MGH8022	lung_MGH8021	lung_MGH8091	lung_MGH9201	lung_MGH1701	lung_MGH100151	lung_MGH1542	lung_MGH100164	bile_duct_CCSW1	bile_duct_CCLP1	bile_duct_SG231	bile_duct_HUCCT1	skin_CHL1	skin_COLO829	skin_A375S2	skin_A101D	skin_SKMEL24	skin_SH4	skin_HS936T	lung_MGH90921	plasma_cell_KMS12BM	plasma_cell_KMS11	plasma_cell_KMS27	plasma_cell_RPMI8226	ovary_TYKNU	ovary_FUOV1	lung_ABC1	lung_A549	lung_HCC15	lung_CALU6	pancreas_CFPAC1	pancreas_BXPC3	pancreas_KP4	pancreas_HUPT4	breast_HCC1937	breast_HCC1806	breast_CAMA1	breast_BT549	breast_MDAMB436	lung_MGH1543	lung_MGH1541	lung_MGH8222	lung_MGH1904	bile_duct_TKKK	bile_duct_SNU478	bile_duct_HUH28	bile_duct_ICC12	lung_NCIH1703	lung_LU65	lung_NCIH1155	liver_HLF	liver_HUH7	liver_JHH6	liver_JHH1	bile_duct_HKGZCC	bile_duct_TGBC52TKB	bile_duct_ICC9	bile_duct_MG984	bile_duct_OZ	bile_duct_SSP25	bile_duct_ICC19	bile_duct_ICC4	brain_MGG75	brain_MGG23	brain_MGG123	kidney_KMRC1	kidney_CAKI1	kidney_KMRC20	kidney_786O	colorectal_SW403	colorectal_RKO	colorectal_MDST8	colorectal_SW948	uterus_HEC1	uterus_AN3CA	uterus_MFE296	uterus_RL952	lung_NCIH2172	lung_HCC44	lung_CORL23	lung_NCIH1299	colorectal_HCT15	colorectal_LS513	colorectal_HT115	colorectal_HT29	upper_aerodigestive_DETROIT562	upper_aerodigestive_BICR22	upper_aerodigestive_CAL27	upper_aerodigestive_HSC3	ovary_OV56	ovary_IGROV1	pancreas_SW1990	pancreas_DANG	pancreas_HUPT3	pancreas_PATU8988T	prostate_LNCAPCLONEFGC	prostate_DU145	prostate_VCAP	prostate_PC3	lung_NCIH1666	lung_NCIH23	lung_SW1573	lung_NCIH1944	lung_PC14	lung_HCC827	lung_LUDLU1	lung_NCIH1975	esophagus_KYSE150	esophagus_TE11	esophagus_KYSE30	esophagus_KYSE510	bone_CAL72	bone_U2OS	bone_SAOS2	bone_SJSA1	uterus_MFE280	cervix_SISO	uterus_ISHIKAWAHERAKLIO02ER	uterus_SNGM	lung_NCIH2170	lung_NCIH2122	lung_NCIH1792	blood_MOLM16	blood_MONOMAC6	blood_JURLMK1	blood_NOMO1	blood_KASUMI2	blood_697	blood_REH	blood_JM1	skin_WM115	skin_C32	urinary_tract_KU1919	urinary_tract_HT1376	urinary_tract_UMUC3	urinary_tract_J82	urinary_tract_RT112	urinary_tract_TCCSUP	urinary_tract_HT1197	urinary_tract_T24	breast_MDAMB453	breast_DU4475	breast_CAL120	lung_NCIH1048	lung_SW1271	lung_NCIH446	lung_NCIH2286	thyroid_8505C	thyroid_8305C	thyroid_FTC133	thyroid_CAL62	breast_MDAMB157	breast_HCC1143	breast_MDAMB468	central_nervous_system_GB1	central_nervous_system_KNS81FD	central_nervous_system_LN229	central_nervous_system_T98G	liver_SNU449	liver_SNU423	liver_HUH1	liver_JHH4	liver_SKHEP1	liver_JHH7	liver_HEP3B217	liver_HEPG2	skin_COLO800	skin_SKMEL5	esophagus_KYSE180	esophagus_KYSE410	esophagus_TE4	esophagus_TE1	ovary_KURAMOCHI	ovary_OVCAR8	pancreas_PANC0403	pancreas_MIAPACA2	pancreas_SUIT2	blood_MV411	blood_KO52	blood_TF1	blood_OCIAML2	cervix_HT3	cervix_CASKI	cervix_C4II	cervix_DOTC24510	lymphocyte_SUDHL4	blood_NALM6	lymphocyte_JEKO1	blood_JVM3	skin_A431	esophagus_OE33	esophagus_TE10	lymphocyte_OCILY3	blood_MEC1	blood_HG3	lymphocyte_SUDHL6	breast_HS578T	breast_KPL1	breast_HCC1954	breast_HCC1395	colorectal_COLO678	colorectal_LS123	colorectal_SW1116	colorectal_CCK81	bone_SKNMC	bone_A673	bone_SKES1	bone_TC71	central_nervous_system_DAOY	central_nervous_system_D283MED	central_nervous_system_PFSK1	central_nervous_system_ONS76	uterus_SKN	uterus_MFE319	kidney_OSRC2	kidney_769P	kidney_RCC10RGB	lung_NCIH1793	lung_NCIH1650	lung_CALU1	lung_NCIH358	skin_WM1552C	skin_MELHO	lung_NCIH2052	lung_MSTO211H	lung_CORL88	lung_SBC5	gastric_KATOIII	gastric_MKN45	gastric_OCUM1	gastric_SNU1	peripheral_nervous_system_SKNAS	peripheral_nervous_system_KPNYN	peripheral_nervous_system_NB1	peripheral_nervous_system_KELLY	kidney_G401	soft_tissue_A204	soft_tissue_KYM1	kidney_G402	lung_NCIH196	lung_NCIH146	lung_SHP77	lung_NCIH82	gastric_HGC27	gastric_AGS	gastric_NCIN87	gastric_IM95	upper_aerodigestive_FADU	upper_aerodigestive_CAL33	upper_aerodigestive_SCC25	upper_aerodigestive_HSC4	cervix_SW756	bone_CAL78	lymphocyte_KARPAS299	gastric_MKN1	plasma_cell_OPM2	plasma_cell_SKMM2	soft_tissue_HT1080	central_nervous_system_LN18	breast_HCC1187	breast_HCC70	blood_HEL9217	blood_HEL	blood_EOL1	gastric_SNU5	gastric_NUGC3	soft_tissue_RD	soft_tissue_RH30	soft_tissue_RH41	lymphocyte_REC1	esophagus_TE8	pancreas_PANC1	kidney_KMRC3	lung_NCIH2291	lymphocyte_L428	unknown_HDMYZ	skin_MCC13	skin_MCC26	prostate_22RV1	kidney_A498	kidney_VMRCRCW	colorectal_SW837	colorectal_LS180	colorectal_SW620	colorectal_COLO320	central_nervous_system_SF295	central_nervous_system_A172	central_nervous_system_GAMG	central_nervous_system_KNS42	blood_JURKAT	blood_PF382	lymphocyte_DEL	blood_SUPT1	central_nervous_system_SW1783	central_nervous_system_42MGBA	central_nervous_system_U87MG	central_nervous_system_U118MG
	KVCQGTSNK	43	54	45	25					51	47	59	28	49	55	33			45	47	62			70		63	68	48	55	61	55	50	57		53	83	61	43	66		68	46	49	45	52	23		50		60	53	50	26				11					-6	26			57	33	42	43			35					65		52	62					11		55	60									55	52	67	71	34	56	49	67	57	50	59	30					51	46	54	48												54				36							62		40	42	47	55	41	28	37	63		45										54	59	53	14		58	12	26	47	23	60	49	53	42	52	56	49	46	68	48	53	68	41	58	58	70	57	44	53	78	24	60	32	28	59	64	56	60	69	68	65	65	64	14	72	76	33	55	55	61	70	65	56	52	64	58	59	69	68	77	50	49	57	45	60	56	45	59	61	62	68	5	46	60	60											64	65	68	69	56	71	62	41	-4	17	68	68	66	42	53	66	60	56	67	28	46	69	69	64	64	72	65	46	73	71	53	40	65	56	18	54	70		44	24	57	60								59	63	67	64					55	46	48					31	39	45	68	64	70	33	66					51	-1	30	54	69	67	66	27	66	26	71	-16	33	20	43	58	57	65	48	64	61	23	37	64	53	35	61					71		60	53	46	55	55	62					67			60			58	61	53	58				54	60							47	56	23	54			44	58	59					62	68	64	31					65	53	55	68
	FSNNPALCNVESIQWR	62	71							47	59	71	47	68	54	42		70	53	62	62	64	58	61	62	62	51	52	43	49	48	47	65	70	56	61	70	70	68	61	53	77	65	77	75	48	50	43	76	57	55	51	52	55		63	59	63	53	61	50		57			63	16	31	55	35	9	44	75	58	56	21	61		68	77							64	75									73	74	81	80	54	75	71	80	78	46	72	55					37	37	58	60	71	73	40	36	58	73	72	66			67	70				74					67	64	74	21	66	78	55	76	56	63	53	71		69	55	49	57	60	74	61	69	27	58	75	78		52	20	82	53	57	72	65	67	61	66	65	58	58	53	72	72	20	72	66		66	64	58	64	53	16	56	42	56	72	61	48	63	43	65	33	53	62	69	55	20	64	72	49	67	63	63	71	58	59	58	77		60	72	69	77	72	62	73	79	50	50	51	55	57	70	73		3	57	64											60	63	69	68	44	55	28	74			74	60	40		55	78	76	57	70	-3	27	82	77	39	49	68	65	51	67	67	38	32	58	36	-8	68	76	73	70	50	-2	12	38	43	63					57	65	61	60					67	69	60							55	75	72	63	71	11					66			71	75	71	79	26	68	57	79			36	48	79	64	70	72	65			43	66	52	29	67					65		56			40	59	73					60	54		57			63	66	63	70				57	66	53	52	48		70	67	34	55		62	54	46	60	60	57	73	77			79	50	66	23					66	30	63	65
	IICAQQCSGR																																																					83			26																							62																	20	29	78	46																																																																																																																																																																				14	17	90
	DEATCK									39	31	59	17									58	36	55	51					47	49	46	59		23	26	58	32	59	29	39																		33		14														9				40																		18	40	71	49	21	47	46	65	49	47	49	37									36	38	-8	7	26	41	51	53																			12	60	39	29	8	41								26	47	10	31				33	27	72	56	34	45	39	23																																																		20		54	26					44	56	52	42																		61	43	61	63								60	58	29	58			62																					22	31	42																																									29	70	-35	20	37	53																																			50	39													53		46			47	37		66	67
	DTCPPLMLYNPTTYQMDVNPEGK		12																															23	3	19	14					46	15	31	59						49	49	62									11	23																	9																	14	56	74	56																																																49																																																		32	31	32	35															19	30	29	31	56	17	58	59																						59	36	59	59	38	46	11	45	24	7	43					51	54	20	35	28	17	65																																				34	30	27							39																																																													41	49																			53	51													23	-9	-10	-44
	YSFGATCVK		66							54	57	68	33	62	58	25		54	47	46	49	32	41	61	51	57	60	51	46	57	51	43	51	57	48	57	67	56	70	32	57	59	39	50	58	39	66	39	64	29	64	80	33	82		69	74	71	65	55	48	25	27												60		70		56	44																	54	70	82	86	33	62	62	78	69	51	67	39					9	42	54	36	56	39	38	32	48	52	69	62								54							75	63	53	51		27		0	24	52								43	46	24	44	60	69	56	44	56	79	46	45	56	48	43	54	60	52	52	51	30	58	61	50	57	62					56	44	49	76	60	64	66	58	70	73	47	56	57	57	61	57			54	4	30	57	35	50	52	37					31	63	64	61	67	49	66	79																						59	60	64	72	49	63	36	67								66	67	32	57	25	24	77	72	47	58	69	58	42	48	53							69	70	60	41										26	54	70	53					55	58	55							45		63	46	-1	16																				63	48	62	39	48			8													21	22	46	64	72	61	32	59								56	54	68				59	60					71				19	54				71	81													49	46	51	64
	NYVVTDHGSCVR																													40	52	55	53	46	29	55	48	43	51	33	22	44	37	37	42						46	48																																													30	46	76	53					55	7	47	-8																																																																																																																37	-4	48	44
	ACGADSYEMEEDGVR		32																			25	11	44	26	26	30	27	25	29	26	13	21	39	29	22	42	15	42	16	37	38	13	42	42	9		11		13	8	28	14									41	43																	15																	31	38	48	47	5	18	30	45	51	18	38	20									40	12	-3	3	31	10	40	35								22							32	53	23	23										25	13	24	25	22	26	-1	27	43	51	37	7	29	54	49	17	43	26	23								48																																		17	18	48	43	20	35	41	33	39	18	54	47																						48	34	54	45	27	27	26	35								9	37	-3	21	6	15	57					37	13	30	39							44	44	43	30										10	32	40	26					34	29	30							34		41	19	-12	18											48	15	40	31	52	41	25																																							22	36										57				44	21				44	41					47	46	28	20
	KCEGPCR																																																																																																20	17	64
	KVCNGIGIGEFK	55	71	46	55					51			39	43	45	53	29	39	51	50	59	43	36	53	45	58	58	47	42	49	45	51	55	50	50	50	61	48	59	42	58	52	43	58	55	53	63	43	63	49	58	59	45	55	63	58	55	60	68	63	43	34	41			46	48	60	46				64	76	64	34	62	73	60	64																	44	47	68	55	38	68	65	64	58	56	50	43					46	57	55	38	51	56	17	27	45	52	56	58								65					46	44	63	76	51	53	47	62	57	47	58	65	31	67	52	38	43	29	44	55	51	41	46	67	72	51	55	60	73	62	46	57	53	52	56	59	59	55	59	57	58	62	66	68	56	37	58	59	63	60	49	59	59		67							57	63	66	69	65	46	63	69	46	67	63	54	58	54	63	63	68	83	56	66	65	71	64	51	65	71					58	62	76	27	55	58	63											71	55	64	64					52	18	65					65	64	67	61	33	31	68	75	35	55	62	69	84	67	60							65	64	55	49	69	67	58	46	64					65	59	74	59					62	59	50							70		61	59	69	61					56		23	58	71	62	69	41	48	56	69	79	38	58	56	65	45	61	53																	41	43	40	55											62	56	62	54				73	55					72	66	56	50	40	59	57	48	51	55	54	58	70	60	8	62	53	55	46					55	40	52	53
	NLCYANTINWK	51	73	16	32					51	54	81	37	74	71	46	20	53	57	59	69	50	57	74	70	61	47	48	55	76	56	47	67	69	68	65	76	73	81	72	78	68	57	51	77	37	67	45	71	83		83	50	84		80	78	77	79	70	61	46	36														79	70	68	80																	68	68	83	74	50	67	69	81	82	86	83	68					42	36	65	57	82	74	43	43	52	62	83	72															77	54	56	51	37	43	35	52		71								68	57	33	56	66	76	48	52	40	77	54	60	42	61	63	69	62	52	62	81	52	87	73	62	74	75					57	49	49	84									65	62	75	73			72	72	58	67									62	82	80	83	79	54	85	87					59	64	59	42														72	74	79	79	66	69	51	63	59	33	80					75	75	60	65	15	23	83	72	40	63	74	72	68	66	67							77	83	62	52										59	70	74	63					68	64	62							70										65	77	50	72	75	68	78	33	67	68	80		24																							45	40	64	78	61	60	41	55								51	74	79				67	79					79		49	57	9	44	60	55		76	76
	CNLLEGEPR		26																							42	46	28	34		28	26	29	42	34	44	45	17	37	38	28	35	53	50	36	37	51	33	26	10	38	35	15	35	42	30	37	44	42	40	24	0	1										55	56	25	22				22																	50	33	58	86					73	45	45	48					34	45	56	34	25	60	10	26	19	10	36	53								25							47		25	39	30	44	29	41		42								25	36	15	42	50	55	33					28	42	29	34	29	44	34	36	38	22	46	44	48	42	45	20	49	48	59						33																									25	42	40	43	53	34	48	58										56	46											49	35	44	37						0	36					64	56	49	43	16	16	60					45	18	54	36							46	49	61	17										38	44	56	32					39	41	43							45																56	22	47	20	54		0																																							50	49										55
CYS 775	EILDEAYVMASVDNPHVCR		42							44			54	31	19	36	16	29	27	23	24	39	12	40	13	31	30	39	31	25	32	33	17	29	29	20	24	9	38	34	32	31	21	41	25	36	19	49	15	32	23	29	21									40	45												22	29	21	39	28	27					64	60	12	23									43	38	31	27	48	49	50	52	24	38	29	23					51	45	32	29	42	63	36	34	35	37	27	11	19	27	21	23				19							31	37	32	22	39	37	37	33	48	40	12	32	19	46	26	49	14	26	28	37	26	33	24	21	32	37	27	21	35	43	23	30	30	31	32	27				32	30	25	21					37	23	29	4									23	35	32	38	34	40	38	53	49	44	43	39	37	36	38	42	30	48	39	27	24	27	31	41	33	31					39	40	51	34														35	29	15	28												45	41	54	37	27	32	22	13	42	26	32	36	41	25	28	61	7	56	43			30	27	40	40	39	23	37	35	45					37	36	40	46					46	47	41					31	38	46	38	29	37	24	17					14	45	36	17	36	32	31	39	33	53	27	41	34	33	29	31	31	32	20	26	12	22	-5	33	18	51	41					34	18	27	26					4	4	-26	5	29			40			13	25	21	21				24	36	30	26	29		10	22	26	29	33	17	28	42		16	17	44	38	62	48	30	26	25	35					26	18	28	30
CYS 818	DNIGSQYLLNWCVQIAK																				50	48	42	39	38	51	31	56	68		27	55	47	43	36	32	40		48			35	43	39	37																																																				39								33		36																																43	35	36	17														42	47	42	37																			47	53	50	48																	38	47	53	57	42	19													55	52	54	48	37	46	47	39																																																																																								54																51	27	41							36	40	41	33																									56			58			46	48	49	38										54	53	60													55	47	53	28
CYS 818 *	CVQIAK	53	65	78	73					77	80	67	70					73	79	54	66	66	74	64	76	74	69	68	64	79		75	71	75	75	73	74	72	86	69	59	70	66	77	78	79	70	61	74	64	87	59		63	64	70	79	72	75	69	73	70	64	61	66	70	66	68	79	72	65	68								72	55	54	62	67	69	56	73	74																									63	64	75	75	75	78	74	81	76	69	72	74	75	71	75	73											63	65	69	64														65	46	57	58	66	63	45																64	67	66	65	72	78	77	74	75	76			69	73	26	68											72	75	81	68													61	59	64	65									68	60	69															71	72	74	67												61	71	54					76	82	71	71	62	73	79	53	73	70	70	80	67	71	65	65																66	63	71					77	70	67	64	61	68	74	64									67	73																																																			81	66											67	76
CYS 939 *	LPQPPICTIDVYMIMVK		47							51			55	53	47	55	44	30	50	54	52	66	52	49	39	56	54	55	57	43	49	56	47	44	46	58	59	59	52	41	50	52	59	61	53	51	51	54	50	50	56	42	39	42	58	49	37					39	26										70	49	62	47	57	29	49	40	71	64	70	68	63	66	59	51									49	57	61	56	64	67	60	63	54	58	47	46									65	58	57	67	64	51	46	61								33							55	69	40	39	50	51	54	39		47								56	53	34	48	54	61	40					58	43	58	56	60	45	25	61				55	57	53	58					49	53	54	55		55							40	35	56	50	43	63	59	38	15	57	38	41	25	26					53	55	51	44	51	48	58	38									75	40	55																			56	24	40					42	53	40	44	42	41	58					44	36	33	45							52	60	66	43	59	49	51	41	67					30	52	55	58					55	65	48					27	32	74	40	55	53	49	37					59	63	47	56			59	28	55					39	42	38	48	45	20																	30	28	69	38					55			59				38	57	35				39	52					54	48	45	49	20	44	57	59	46	-5	-2					41	51	53	40					55	51	52	59
CYS 950 *	CWMIDADSRPK		64							68	45	61	73	51	50	44	21	44	53	50	58	50	61	51	58	52	53	50	57	58	46	59	53	56	54	66	64	44	60	35	54	49	65	61	60	42	60	44	45	54	53	46	39	55	48	43	48	41	45	32	39	33	30										53	53	45	38	55	29	48	51					43	31	58	59									59	44	55	60	54	55	48	56	58	67	59	59					62	57	67	73	63	52	65	73	65	66	53	67				51				44		42			46	55	53	62	46	41	60	59	56	54	55	63		46		53	68	43	41	54	59	44	62	57	60	43	51	43	50	51	56	43	58	58	56	49	54	62	47	38	57	60	61	59	62			62	58	47	61	65	73	32	54	55	52					62	55	65	66	60	38	59	45	23	48	51	54	48	51	52	51	54	35	63	66	61	51	61	59	65	68					41	56	61	33														64	61	53	48	55	39	69	55	58	27	51	62	30	2	43	51	63	70	63	16	34	60	37	50	61	53	57	56	56	60	63	56	62	52	33	51	65	69	59	59	38	44	37	39	46					47	62	61	62					63	61	62					-3	16	61	61	53	48	46	41					66	45	13	61	54	56	66	23	59	69	66	19	29	47	58	53	63	60	53	67	26	18	36	45	51	64	46					64	51	49	39	44	48	67	59	55	63	73	70	65			66			61	61	53	58				53	56					68	66	70	63	23	55	49	53		49	47	55	62	22	15	55	62	68	44					62	56	71	69
CYS 1049	TPLLSSLSATSNNSTVACIDR		38											29	15	20	20	23	23	24	25	36	28	29	24	41	36	37	34	27	24	36	33	30	29	27	39	42	22	37	22	41	32	33	29	35	22	22	36	38	37	21	20					20	17	19	15	24	32												43				26	41																	48	41	45	38					45	33	41	36					40	37	38	36	48	61	36	33	42	27	35	42								21							44	33	25	23			39		40	48								37	40	31	-4	33	53	35	33	22	50	37	39	40	26	36	38	40	57	50				40	50	44	34					40	24											44	44	33	43			33	21	19	26	37	37	25	24					35	30	29	26	37	38	46	51					28	35	46	32														41	41	31	34	50	35	36	48	51	34	40					30	43	50	37	31	39	45					40	48	34	39							39	39	33	28			25	32	40					28	35	34	39					39	47	34							50		38	39	29	32					31	55	24	32	60	38	54	29	34	44	51	28	34			49	46	39	30																	33	34	36	29					36			31				36	43	34				28	31					34	37	26				32	10		39	46													43	14	17	29
CYS 1058	NGLQSCPIK		49															44	31	35	53	33	44	49	53	47	47	50	49	48	49	55	56	49	54	51	63	59	61		40	45	30	52	55	25		40		50	51	49	47					60	62	47	47	21	23												52		60	44	35	55																	46	46	58	53	48	55	49	59	57	49	55	52					-3	36	59	41	60	36	28	40	39	33	53	58								42							66	59	51	45	52	56	42	47	44	52								53	54	26	49	53	79	61	42	25	65	55					56	48	46	56				48	57	63	55	35	42	59	64	54	41	65	67	49	38	58	51					51	46	49	55			50	51	37	39													63	44	67	80																						56	52	59	55								42	43	20	57	52	57	49	49	32	36	58															53	54	57	38																		52	53	44																	41	32	37	46	71	44	63	21	45							39	27	36	16																					19	38		-5																							49	18	45				54	57

EGFR	DNA copy number	1.13214108944071	1.37498330624223	1.24572085783884	1.24224395966337	1.68444004061865	1.59963421783799	1.17388484147859	0.874920296105918	0.988816187501611	1.27098399819888	1.01175802712821	1.4538099444745	0.984270692210935	0.975962646098449	1.10746714674445	1.03312271261213	1.1186822667286	1.06785008837962		1.3249833476519	0.646214728123304	1.27395233560188	1.03269886406905	1.08483062560747		1.1363800308231	1.03601767099829	1.18547582196931	1.17039500995853		1.13837406659744		1.13844228403266		1.33741354129278	1.34614009631025	1.03205743806574	1.32399698231109	1.03885965356006	1.30376001373616	0.903342897293527		1.1401442221705	1.34841804456683		1.02807853170218	1.2177298021841														0.916269762161808	1.51844034105499	1.30965622200778	1.2424798166596	1.02799699196884	0.98672563685263	1.06765555525935	1.24515651476054	0.937342648868863	1.06933340507899		1.65803696767012	1.3120164150165	1.08932902973738	0.894771678081665	1.49545802447857	1.21737241972169	1.0243765219868	1.13161970087697							1.19730781517682	1.00588897031684	0.847937394705937	1.00309130483451	1.12781331205935	0.987816384030014	1.01176508396365	0.968431623494522	1.23480101649662	0.98457782180227	1.62613747165809	1.06616910900278	3.67085335550115		1.18306186729702	0.753113357912793	1.04635251113944	1.06860596151054	1.38058953897153	1.10814840456332	1.18320064943176	1.03994204933279	1.0058081446376	1.03812377666003	1.29869014552301	0.984533306127092									1.1954405112586	1.01265855189498	0.823854054388994	1.28392899923897		1.25066108845455		1.4430802324478	1.02921545334302	0.958576317668148	1.18856241217064		1.4265727611964	1.24658850228503	0.995541410905578	1.21288092436168	1.41408106823655	0.812037513999711	1.49547029452661	1.11552599125312	1.16284335703923	0.850486294669871	0.89724951976598	1.15879011203618	1.27007584035348	0.959049699629263	1.28473417292692	0.963539203659212	1.11906264697067	1.16831914940265	1.15543864386256					1.84819651729354	1.26703662968055	0.885191261120428	1.11119736960365	1.47949304338984	1.67509744063324	0.986897048090632	1.09265724268325	1.25399044143443	1.17981971128085	1.29977713329763	0.971277240265016	1.06132125827399	1.29816970603445			1.24382493384887		1.26652266420779				1.12715714464805	1.17447456081733	1.01136138678026	1.08889712070188	0.945486021650816	1.02351151476622	1.37171495406896	1.34246618736259	1.12175148519376	1.30720269562121	1.04257885304567	1.03476964133785	1.08994662031966	1.31308694115295	1.03313549638331	0.93013180803371	0.998881933578161	1.27855663713967	1.37489621108669	1.23910000066975	1.12936199718175	1.02217382661782	1.83206147214113	1.71605046175682	0.88474376485063	1.11553568386958	1.26563492834005	1.57317869475917	1.04123134969887	0.961309145476694	1.0189690896361		1.16963941578844	1.29892637371904	1.11138160172144	1.32075811092868	1.11003228937001	0.970516563480336	1.80482645577723	4.87105628311712	1.92790178298606	1.58877529165723	1.3782889231592	1.76613804184907	2.87242510842576	0.85453269031572	0.60227075543016	1.30363746151768	0.926676534021907	1.01145411137857	1.25605943081763	1.1386098374483	1.03818688184649	0.982141912961883	1.22620504896882	1.28358224183162	1.6902608245943	1.15532678011902	1.04711919478455	1.00591106010385	0.998733556350701	0.600180932348743	0.992863737465231	1.00004850081523	0.940374458147165	1.58738351527405	0.990385253495311	0.754181871658662	1.17638424956771	1.02843735921052	0.922548061680918	1.03624259978459	1.20035033972704	0.949603684256136	0.95665583514226	1.05514991093918	1.21748811996981	1.07018582850024	1.09072145781975	1.02533206872573	1.17394608762845	1.08242697247394	0.989258289333001	1.52539349147004	1.30839362964736	1.03634918361876	1.36225617543244	1.4488261517161	4.72970131952453	1.62661141054242		1.53923598862816	1.19559406383536	1.18684911966372	1.13217915319333	1.06750496540728	1.64657818465225	1.3116401853701	0.980327976254982	1.45517735103448	0.958507872976138	1.42408971438124	1.42762298079611	1.98459325697518	1.16050358808926	2.04818420276846	1.72046154537756	0.931350762405542	0.948541761830692	1.08070842688267	1.20270263932001	1.12478890637203	0.9854545718296	0.993713755462081	0.902548790038864	0.983034936634405	1.00725113136815	1.29797348612159	1.04066081931771	1.2077579935055	1.26917932212179	0.98968662909803	1.11269437201635	0.998562716660001	2.46576579187809	1.33059225816469	0.835794101933556	1.00400002993162	1.20627401599641	1.03329146710786	1.30344115477616	1.12896193974014	0.906175434670948	1.20720745934413	1.05565266363002	1.1762041727514	1.25929530825758	1.31082226363693	1.08986443810086	1.0001770108578	0.902238168981873	1.21593672373524	0.879290752735597	1.83050127456695	0.600863604389119	1.07160528092201	1.13837788670284	1.09125679344545	1.04781294446491	1.22590848582056	1.04875031249068	1.13923817049139	1.21319993219468	1.50668543175063	1.25611291241995	0.94235667801913		1.10973712145262	0.814501020522694	1.097427648038	1.00324263594242	1.06591471364121	1.50038199574831	1.58263144334729	1.34066873031546	1.00680849017273	1.41204336994659	1.02492668761681	1.09366983865764	1.26645573215289	0.996421449268709	1.03396462716444	1.04039413101106	1.01651900251234	1.22128388422674	1.05592667775521	1.38178168628533	1.09167446662884	1.04812895194596	1.04721363784726	1.04574397677306	1.38396919201514	1.44128032714227	1.56420720604353	1.16702228891946	1.45791237983425	1.13617563024623	0.847965838034174	1.02499737978761	1.27572132064029	1.21732682548801	1.03625950921976	1.00386917450942	1.30477699453978	1.47390430939634	1.68936491856674	0.824459400534833	0.82544057795804	0.971918237411496	1.65192487743215	1.42685348729808	1.28581982527492	1.13899467124737	1.08206496546822	0.995570321435116	3.3964595834401	1.32520146577464	1.01439460278888	1.40534924266278	0.962756005728244	0.900489805532847	0.994293331375472	1.17314225746997	1.27600367812976	1.45764157610389	1.28167076250546	1.04150435453633	1.04289018208103	1.41624242964539	0.88693604241673	1.59039560309584	1.64043712721341	1.4926819863469	1.16206493701859	0.997813659166362	0.998995350047962	1.16443776897439	1.14891171897134	1.28338512424257	1.21215553719339	1.04819711892221	1.2831211931026
EGFR	DNA mutation status	0	0	0		1	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0		0	0	0	0		0		1		0	0	0	0	0	0	0		0	0		0	0														0	0	1	0	1	0	0	1	0	0		0	0	0	0	0	0	0	0							1	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0									0	0	0	0		0		0	0	0	0		0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0					0	0	0	0	0	0	1	0	0	0	0	0	0	0			0		0				0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	1	1	0	1	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	1	0	0	0	1	0	0	0	0	0	1	0	0	0	1	1	0	1		0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	2	0	0	0	0	1	0	1	1	0	0	0	0	1	0	0	1	0	0	0	0
EGFR	RNA expression	1.4905701304462	4.34340782229781	0.0565835283663675	0	2.63459326844576	0.0976107966264223	0.189033824390017	0.176322772640463	1.43295940727611	2.20789285164133	4.50842865253186	0.75702324650746	4.16108148227718	4.8703647195834	5.69682846458871	0.367371065648529	1.35049724708413	3.3533232911629		4.16188768237689	5.50493813164961	5.60821785302146	4.3037807481771	5.31324585178756		4.03298241669943	5.96624587322494	5.44824022521607	3.88752527074159		5.61087719947195		5.18269229751619		4.96069703930431	7.41125674622079	5.9902741833186	6.13975597548131	1.4541758931858	5.37851162325373	5.64270157183323		4.66845955691538	6.32750773458721		4.2637856138908	1.58014548442338														0.150559676575381	0.970853654340484	0.124328135002202	0.16349873228288	0.495695162624069	0.344828496997441	2.58255600301406	1.55090066464752	0.124328135002202	0.070389327891398		4.99909803370561	2.90303827011291	1.96716860753263	0.263034405833794	4.44028782084042	0.0840642647884745	3.67919857056692	5.72683121703249							4.39780296186249	5.07809742302666	0.137503523749935	0.176322772640463	0.070389327891398	0.150559676575381	0.286881147788161	0.070389327891398	0.263034405833794	0.238786859587116	5.93522399406003	4.10349763970334	9.25802418543952		4.8972404255748	3.33913738491959	3.64385618977473	5.55887985347544	4.81352468929781	5.55397480823747	5.89602960297675	5.86690797814317	0.124328135002202	0.150559676575381	0.20163386116965	0.150559676575381									4.58496250072116	4.61470984411521	4.34127418369217	5.97269265400426		0.238786859587116		2.93734439215023	2.10097764772482	0.16349873228288	1		0.137503523749935	0.0976107966264223	0.070389327891398	0.333423733725192	3.45811948117451	4.31976242766925	6.50827017556779	5.34589308568741	4.99367436175059	4.35825558670513	5.17032569441556	5.9706236144706	3.47767732756531	4.32984117653063	4.98732086592925	5.30669970727279	0.0976107966264223	5.52136487844622	4.71808758396052					7.06856333533888	5.50112063427539	3.611172380044	5.62410089462811	5.46139758992616	6.24792751344359	2.74631276642546	5.9469647411558	5.47378691161437	5.94649694120329	5.10810622368613	6.10307794659757	4.62819033461521	5.01256867350306			5.18388345903223		5.65477921695952				4.26453643099903	4.16430358309365	6.39574832817903	5.33842441478356	2.13093086982645	1.33342373372519	5.54751152364422	3.89627184880738	3.02856915219677	4.58676474335514	1.49569516262407	6.28188367456292	4.57893871309339	5.39437694495706	4.85598969730848	3.4867143730307	3.92409988564074	3.74631276642546	3.48928602262588	3.44493204894218	5.99909803370561	4.93734439215023	8.08719761557795	7.69146437341683	4.98823022306046	4.49121175600309	4.41683974191283	5.07937811111865	5.39780296186249	6.15987133677839	4.45022149589718		2.17312743348066	4.82883464946806	5.47021145739054	3.80322703643493	5.42021289061078	3.09929520433778	6.56757586852411	9.67364475243824	6.30268461411838	5.32373033752135	6.80309784950483	6.13996056954546	8.35952995532291	4.30669970727279	3.48026512205446	2.16349873228288	3.08746284125034	4.06695024392463	2.63226821549951	5.70182625841205	3.72574115650395	5.09043004232162	1.50589092972996	3.59454854955035	5.79181407116183	0.137503523749935	0.124328135002202	0.189033824390017	0.137503523749935	0.150559676575381	0.137503523749935	0.124328135002202	0.137503523749935	1.83995958748953	0.799087306074004	5.62585493136806	7.04494049127973	5.35614381022528	4.78764141448333	5.6564963705535	4.85449441815488	5.9143253300853	5.10475598696226	0.150559676575381	0.214124805352847	5.35085080548338	5.50652577904312	5.17472598770613	0.0565835283663675	5.15340002773506	5.9979697822671	6.58345891013077	5.18269229751619	5.59006301881225	3.55704241526372	6.31795521831244	9.18256816161399	3.94579495674006		4.42223300068305	5.33556900555675	5.36946648365072	5.21529030565123	3.93734439215023	5.88386515450979	5.66931028620247	3.80426011563474	5.48446041312882	1.83187724119167	0.632268215499513	0.545968369105293	7.20084957463721	5.07081863753328	5.30997649237056	6.20554891117303	2.07724299893246	4.86393845042397	4.43028527297778	3.88264304936184	5.39231742277876	0.0840642647884745	0.111031312388744	0.214124805352847	0.137503523749935	4.11270013274936	5.48574882137778	5.4757334309664	5.9797967182782	0.422233000683048	0.124328135002202	0.150559676575381	0.124328135002202	7.6442889333787	5.32373033752135	4.63343121035563	0.16349873228288	0.070389327891398	0	0.37851162325373	4.90785207184596	1.14404636961671	5.12969515665378	4.70321146739115	5.77214959078454	4.603477988254	4.47638168756724	2.72465027173297	0.176322772640463	0.31034012061215	0.263034405833794	0.111031312388744	5.29975751183932	0.495695162624069	0.286881147788161	5.32840565895857	3.72246602447109	4.78711898281334	6.97911075501579	5.27500704749987	7.43162295971329	4.84096670448742	6.07831095000713	6.47654370621426	3.97636363573276		0.111031312388744	5.5963388642052	5.37989816352469	1.22650852980868	0.704871964456353	4.74038793246835	4.63923216324928	5.74416109557041	6.14139191617073	5.54565954002547	2.72900887033786	3.1811025507538	2.85798099512757	0.298658315564515	0.622930350920177	0.0840642647884745	0.176322772640463	5.10433665981474	0.111031312388744	2.49825086752783	0.0976107966264223	0.150559676575381	3.80219321694182	5.10726939359254	4.26077843189343	6.55366768848306	7.47986108501682	5.17592374206376	7.69285956238577	5.69181329717138	3.82883464946806	0.124328135002202	5.25323293853803	0.150559676575381	0.124328135002202	4.29572302453997	4.77873424411784	5.13873256972024	6.34216358328935	0.0976107966264223	0.0976107966264223	0.124328135002202	5.53760669149529	5.4541758931858	4.66505161428921	3.03738222200308	0.20163386116965	2.28688114778816	7.88758619407687	5.85024935828633	6.92041240816079	6.10349763970334	0.0976107966264223	4.35543919724869	4.28466218548316	3.93922657772821	2.8073549220576	5.44028782084042	6.3743439890385	4.16188768237689	3.89917563048051	0.0976107966264223	0.176322772640463	4.88215391728701	5.04745114041639	6.68355610749568	3.62527048937469	0.0976107966264223	0.22650852980868	0.20163386116965	0.286881147788161	4.98686597232911	4.85648777949568	5.10894256866079	5.57288966842058
EGFR	CRISPR gene dependency	0.04	0.18	0.03				0.02	0.03		0.06		0.03	0.07	0.75	0.02	0.02	0.08	0.31			0.05	0.33	0.02	1.00		0.08	0.84	0.79			1.00		0.97		0.06	0.99		0.62	0.03	0.08	0.87		0.03	0.07		0.66	0.17														0.09	0.00	0.10	0.08		0.01	0.03		0.10	0.18		0.04		0.30	0.14		0.04	0.04	0.03							0.09			0.07	0.09	0.02	0.04	0.05	0.05		0.06	0.71	0.31		0.75	0.42	0.15	0.57	0.26	0.97	0.16	0.14	0.09	0.01	0.02	0.03									0.34	0.04	0.05	0.97					0.22	0.04	0.14			0.01	0.08	0.05	0.00		0.10	0.19	0.03	0.19	0.15	0.03	0.02	0.96	0.33	0.31	0.02	0.03	0.08					0.65	0.98		0.09	0.02	0.26	0.04	0.02	0.02	0.09	0.99	0.95	0.81	0.80			0.60		0.94				0.20	0.84	0.52	0.19	0.02	0.03	0.05	0.10	0.09		0.01	0.58	0.21	0.11	0.07	0.07	0.02	0.51	0.90	0.57	0.81	0.84	0.81	0.79		0.11	0.26	0.06	0.83	0.31	0.03		0.07	0.10	1.00	0.02	0.03	0.11	0.99	0.06	0.87	1.00	0.24	0.48	0.85	0.13	0.01	0.11	0.08	0.06	0.03	0.78	0.08	0.22	0.06	0.03	0.75			0.03	0.01		0.04	0.04	0.03	0.04	0.01	0.07	0.97	0.16	0.03	0.03	0.12	0.04	0.01	0.01	0.07	0.05	0.02	0.03	0.03	0.12	0.06	0.02	0.16	0.05	0.04	0.17	0.06	0.05		0.29	0.06	0.28	0.02	0.50	0.10	0.04	0.05		0.02	0.05		0.25	0.19	0.03	0.22	0.27	0.13	0.94	0.06	0.54	0.02		0.09	0.01	0.03	0.44	0.90	0.88	0.01	0.11		0.02	0.95	0.52	0.71		0.17	0.04		0.01	0.02	0.67	0.05	0.53	0.24	0.86	0.17	0.06	0.08		0.01	0.05	0.03	0.10	0.02	0.02	0.57	0.15	0.91	0.40	0.24	0.07	0.14	0.41		0.11	0.22	0.03			0.13	0.02	0.11	0.06	0.03	0.01	0.06	0.05			0.03	0.06			0.03	0.18	0.03	0.11	0.44	0.88	0.06	0.89	0.61	0.99	0.17	0.10	0.20		0.02	0.09	0.06	0.05	0.01	0.02	0.03	0.03	0.06	0.10	1.00	0.02	0.23			0.94	0.07	0.25	0.15	0.15	0.05	0.04	0.02	0.02		0.02	0.51	0.54	0.02	0.03	0.05	0.07	0.07	0.03	0.03	0.07	0.03	0.05		0.03	0.06	0.03

Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
EGFR	P00533	7syd	2.4	13.3	19.0	11.0	30.0	0.1	-1.9	-3.5	-0.2	-0.4	-0.9	27.5	-124.1	-135.1	160.8	E	0.0	0.0	0.1	0.1	0.1	0.6	0.0
EGFR	P00533	7syd	1.9	19.9	11.0	25.0	36.0	0.1	-1.0	-0.3	-0.2	-0.1	-0.9	45.2	40.8	-143.3	164.8	N/A	0.3	0.0	0.3	0.0	0.0	0.5	0.0
EGFR	P00533	7syd	2.0	27.5	18.0	5.0	23.0	0.1	-0.3	-0.1	-0.2	-0.1	-0.4	73.1	-95.1	-105.3	168.2	S	0.2	0.0	0.0	0.2	0.2	0.4	0.0
EGFR	P00533	7syd	2.3	8.4	17.0	14.0	31.0	0.0	-1.5	-0.2	-0.3	-0.2	-0.8	39.3	-173.8	-89.3	115.9	N/A	0.2	0.2	0.4	0.2	0.0	0.0	0.0
EGFR	P00533	7syd	2.0	17.6	25.0	12.0	37.0	0.1	-0.3	-0.1	-0.1	-0.1	-0.3	55.1	-90.4	-66.7	147.0	P	0.0	0.0	0.3	0.3	0.3	0.0	0.0
EGFR	P00533	7syd	2.7	12.9	19.0	14.0	33.0	0.1	-1.5	-0.3	-0.3	-0.2	-0.9	33.6	-173.7	-100.1	120.4	E	0.2	0.0	0.5	0.2	0.0	0.2	0.0
EGFR	P00533	7syd	5.1	0.0	20.0	20.0	40.0	0.1	-3.0	-0.4	-0.4	-0.2	-0.7	40.3	178.3	-78.7	109.5	E	0.0	0.0	0.3	0.2	0.0	0.2	0.3
EGFR	P00533	7syd	1.8	38.2	19.0	13.0	32.0	0.2	-0.2	-0.1	-0.2	-0.1	-0.2	43.2	-60.1	-79.6	171.8	N/A	0.0	0.0	0.3	0.0	0.3	0.3	0.0
EGFR	P00533	7syd	1.9	35.1	11.0	6.0	17.0	0.2	-2.8	-0.7	-0.1	-0.1	-0.4	20.3	-141.7	-69.0	145.7	P	0.1	0.3	0.1	0.1	0.1	0.0	0.1
EGFR	P00533	7syd	2.3	15.0	22.0	13.0	35.0	0.1	-1.4	-2.5	-0.5	-0.1	-0.5	16.6	-110.7	-86.4	145.7	E	0.0	0.0	0.5	0.2	0.0	0.3	0.0
EGFR	P00533	7syd	2.4	6.2	15.0	27.0	42.0	0.0	-1.7	-0.4	-0.4	-0.1	-0.4	60.2	39.3	-94.7	176.7	N/A	0.3	0.0	0.0	0.0	0.0	0.3	0.3
EGFR	P00533	7syd	2.4	5.5	16.0	13.0	29.0	0.0	-0.3	-0.9	-0.1	-0.1	-0.2	54.6	-111.1	-93.2	52.9	N/A	0.2	0.2	0.2	0.2	0.0	0.2	0.0