DrugMap: GAPDH (KB02)

name	peptide	breast_AU565	breast_CAL148	breast_ZR751	breast_MCF7	breast_HDQP1	breast_HCC1419	breast_CAL51	breast_MDAMB231	breast_BRX142JUNE	breast_BRX330FEB	breast_BRX50	breast_BRX82	breast_BRX394JUNE	breast_BRX29	breast_BRX330JAN	breast_BRX401	breast_BRX68	breast_BRX390	breast_BRX250MAY	breast_BRX211MAY	breast_HCC1937	breast_HCC1806	breast_CAMA1	breast_BT549	breast_MDAMB436	breast_MDAMB453	breast_DU4475	breast_CAL120	breast_MDAMB157	breast_HCC1143	breast_MDAMB468	breast_HS578T	breast_KPL1	breast_HCC1954	breast_HCC1395	breast_HCC1187	breast_HCC70
CYS 152	IISNASCTTNCLAPLAK	84	88	83	57	73	72	49	47	82	86	85	80	70	78	70	82	79	83	91	87	33	39	34	47	49	47	24	36	27	28	74	38	33	57	53	71	65
	LTGMAFRVPTANVSVVDLTCR	-21	-7	-3	-32	-12	-20	-12	-21	0	8	-1	-17	3	-11	15	27	-12	-1	-23	-27	19	0	42	0	-4	-10	24	3	2	11	4	2	-3	-16	1	-21	-9

GAPDH	DNA copy number	1.12993211827834	1.03333749433465	1.60819369529188	0.867728300428096	1.27614340369717	1.1335598051874	1.05058693207369	0.897811838795685													1.3119889420408	0.923937733722298	0.630334745015947	0.987384147535777	1.49940460803342	1.00146023825023	1.0368227523749	1.42548972559294	0.557598525849248	0.897247667404828	0.922693103867022	0.876591627409386	0.906235601992848	1.32827125920656	1.08248133331508	1.43337326855144	1.01511334196657
GAPDH	DNA mutation status	0	0	0	0	0	0	0	0													0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GAPDH	RNA expression	12.6619561972773	11.3695973462787	12.363696744839	11.7225087172296	11.186361891253	11.8788938994169	11.9686307973609	12.3964977523572													12.5311621152047	10.4972530840723	10.8839415017191	11.4034381630083	12.6940748927275	11.8694010597781	11.6025596915811	12.076949173741	10.6951412746954	11.1372473406647	11.6734857573378	12.6321545915191	11.7288558614776	12.6854277367763	12.1101243858087	11.6379833037779	11.7918547603173
GAPDH	CRISPR gene dependency	0.98		0.95	0.71		0.82	1.00	1.00													0.89	0.97	0.59	1.00	0.99	0.77	0.97	1.00	0.99	0.99	0.99	1.00	0.99	0.84	0.77	1.00	0.54

Cysteine	Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Pocket Volume (Å^3)	Presence at Interface	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
	GAPDH	P04406	6ynd	7.2	0.0	25.0	24.0	49.0	0.0	-2.5	-2.2	-0.6	-0.5	-0.9	37.5	-135.7	-134.8	154.6	E	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.7	0.0