DrugMap: EGFR (KB05)

name	peptide	skin_A375	skin_RPMI7951	skin_SKMEL2	skin_HMCB	skin_SKMEL3	skin_G361	skin_UACC257	skin_SKMEL30	skin_MEWO	skin_UACC62	skin_LOXIMVI	skin_WM2664	ovary_TOV21G	ovary_OVTOKO	ovary_EFO21	ovary_OVK18	ovary_OV90	ovary_PEO1	ovary_OAW28	ovary_OVCAR4	ovary_SKOV3	ovary_OVISE	ovary_NIHOVCAR3	ovary_EFO27	bile_duct_ICC21	bile_duct_ICC137	bile_duct_ICC10	bile_duct_ICC106	bile_duct_SNU245	bile_duct_ICC11	bile_duct_ICC108	bile_duct_ICC24	bile_duct_TGBC1TKB	bile_duct_ICC20	bile_duct_ICC8	bile_duct_KMCH1	ovary_OVKATE	ovary_OVCAR5	ovary_A2780	ovary_CAOV3	ovary_MCAS	ovary_OVCA429	ovary_OAW42	soft_tissue_RKN	bile_duct_ICC26	bile_duct_TFK1	bile_duct_ICC3	bile_duct_ICC18	lung_MGH0061	lung_NCIH3122	lung_MGH0651	lung_MGH0261	lung_MGH0732	lung_MGH0653	lung_MGH9153	lung_MGH0752	lung_MGH97967	lung_MGH9521R	lung_MGH92431	lung_MGH91621	skin_COLO792	skin_MELJUSO	skin_COLO679	skin_A2058	skin_SKMEL28	skin_IGR1	skin_HS944T	skin_IGR37	skin_RVH421	skin_IPC298	skin_WM793B	breast_AU565	breast_CAL148	breast_ZR751	breast_MCF7	breast_HDQP1	breast_HCC1419	breast_CAL51	breast_MDAMB231	breast_BRX68	breast_BRX390	breast_BRX250MAY	breast_BRX211MAY	skin_MEL182	skin_MEL167	skin_IGR39	fibroblast_HS839T	blood_CMK	blood_THP1	blood_U937	blood_MONOMAC1	blood_KASUMI1	blood_MOLM13	blood_P31FUJ	blood_OCIAML5	bile_duct_SNU1079	bile_duct_RBE	bile_duct_YSCCC	bile_duct_ETK1	bile_duct_ECC2	bile_duct_EGI1	bile_duct_SNU869	bile_duct_SNU1196	bile_duct_OCUG1	bile_duct_GB2	bile_duct_SNU308	bile_duct_G415	lymphocyte_HT	lymphocyte_A3KAW	lymphocyte_RL	lymphocyte_KARPAS422	lung_MGH8022	lung_MGH8021	lung_MGH8091	lung_MGH9201	lung_MGH1701	lung_MGH100151	lung_MGH1542	lung_MGH100164	bile_duct_CCSW1	bile_duct_CCLP1	bile_duct_SG231	bile_duct_HUCCT1	skin_CHL1	skin_COLO829	skin_A375S2	skin_A101D	skin_SKMEL24	skin_SH4	skin_HS936T	lung_MGH90921	plasma_cell_KMS12BM	plasma_cell_KMS11	plasma_cell_KMS27	plasma_cell_RPMI8226	ovary_TYKNU	ovary_FUOV1	lung_ABC1	lung_A549	lung_HCC15	lung_CALU6	pancreas_CFPAC1	pancreas_BXPC3	pancreas_KP4	pancreas_HUPT4	breast_HCC1937	breast_HCC1806	breast_CAMA1	breast_BT549	breast_MDAMB436	lung_MGH1543	lung_MGH1541	lung_MGH8222	lung_MGH1904	bile_duct_TKKK	bile_duct_SNU478	bile_duct_HUH28	bile_duct_ICC12	lung_NCIH1703	lung_LU65	lung_NCIH1155	liver_HLF	liver_HUH7	liver_JHH6	liver_JHH1	bile_duct_HKGZCC	bile_duct_TGBC52TKB	bile_duct_ICC9	bile_duct_MG984	bile_duct_OZ	bile_duct_SSP25	bile_duct_ICC19	bile_duct_ICC4	brain_MGG75	brain_MGG23	brain_MGG123	kidney_KMRC1	kidney_CAKI1	kidney_KMRC20	kidney_786O	colorectal_SW403	colorectal_RKO	colorectal_MDST8	colorectal_SW948	uterus_HEC1	uterus_AN3CA	uterus_MFE296	uterus_RL952	lung_NCIH2172	lung_HCC44	lung_CORL23	lung_NCIH1299	colorectal_HCT15	colorectal_LS513	colorectal_HT115	colorectal_HT29	upper_aerodigestive_DETROIT562	upper_aerodigestive_BICR22	upper_aerodigestive_CAL27	upper_aerodigestive_HSC3	ovary_OV56	ovary_IGROV1	pancreas_SW1990	pancreas_DANG	pancreas_HUPT3	pancreas_PATU8988T	prostate_LNCAPCLONEFGC	prostate_DU145	prostate_VCAP	prostate_PC3	lung_NCIH1666	lung_NCIH23	lung_SW1573	lung_NCIH1944	lung_PC14	lung_HCC827	lung_LUDLU1	lung_NCIH1975	esophagus_KYSE150	esophagus_TE11	esophagus_KYSE30	esophagus_KYSE510	bone_CAL72	bone_U2OS	bone_SAOS2	bone_SJSA1	uterus_MFE280	cervix_SISO	uterus_ISHIKAWAHERAKLIO02ER	uterus_SNGM	lung_NCIH2170	lung_NCIH2122	lung_NCIH1792	blood_MOLM16	blood_MONOMAC6	blood_JURLMK1	blood_NOMO1	blood_KASUMI2	blood_697	blood_REH	blood_JM1	skin_WM115	skin_C32	urinary_tract_KU1919	urinary_tract_HT1376	urinary_tract_UMUC3	urinary_tract_J82	urinary_tract_RT112	urinary_tract_TCCSUP	urinary_tract_HT1197	urinary_tract_T24	breast_MDAMB453	breast_DU4475	breast_CAL120	lung_NCIH1048	lung_SW1271	lung_NCIH446	lung_NCIH2286	thyroid_8505C	thyroid_8305C	thyroid_FTC133	thyroid_CAL62	breast_MDAMB157	breast_HCC1143	breast_MDAMB468	central_nervous_system_GB1	central_nervous_system_KNS81FD	central_nervous_system_LN229	central_nervous_system_T98G	liver_SNU449	liver_SNU423	liver_HUH1	liver_JHH4	liver_SKHEP1	liver_JHH7	liver_HEP3B217	liver_HEPG2	skin_COLO800	skin_SKMEL5	esophagus_KYSE180	esophagus_KYSE410	esophagus_TE4	esophagus_TE1	ovary_KURAMOCHI	ovary_OVCAR8	pancreas_PANC0403	pancreas_MIAPACA2	pancreas_SUIT2	blood_MV411	blood_KO52	blood_TF1	blood_OCIAML2	cervix_HT3	cervix_CASKI	cervix_C4II	cervix_DOTC24510	lymphocyte_SUDHL4	blood_NALM6	lymphocyte_JEKO1	blood_JVM3	skin_A431	esophagus_OE33	esophagus_TE10	lymphocyte_OCILY3	blood_MEC1	blood_HG3	lymphocyte_SUDHL6	breast_HS578T	breast_KPL1	breast_HCC1954	breast_HCC1395	colorectal_COLO678	colorectal_LS123	colorectal_SW1116	colorectal_CCK81	bone_SKNMC	bone_A673	bone_SKES1	bone_TC71	central_nervous_system_DAOY	central_nervous_system_D283MED	central_nervous_system_PFSK1	central_nervous_system_ONS76	uterus_SKN	uterus_MFE319	kidney_OSRC2	kidney_769P	kidney_RCC10RGB	lung_NCIH1793	lung_NCIH1650	lung_CALU1	lung_NCIH358	skin_WM1552C	skin_MELHO	lung_NCIH2052	lung_MSTO211H	lung_CORL88	lung_SBC5	gastric_KATOIII	gastric_MKN45	gastric_OCUM1	gastric_SNU1	peripheral_nervous_system_SKNAS	peripheral_nervous_system_KPNYN	peripheral_nervous_system_NB1	peripheral_nervous_system_KELLY	kidney_G401	soft_tissue_A204	soft_tissue_KYM1	kidney_G402	lung_NCIH196	lung_NCIH146	lung_SHP77	lung_NCIH82	gastric_HGC27	gastric_AGS	gastric_NCIN87	gastric_IM95	upper_aerodigestive_FADU	upper_aerodigestive_CAL33	upper_aerodigestive_SCC25	upper_aerodigestive_HSC4	cervix_SW756	bone_CAL78	lymphocyte_KARPAS299	gastric_MKN1	plasma_cell_OPM2	plasma_cell_SKMM2	soft_tissue_HT1080	central_nervous_system_LN18	breast_HCC1187	breast_HCC70	blood_HEL9217	blood_HEL	blood_EOL1	gastric_SNU5	gastric_NUGC3	soft_tissue_RD	soft_tissue_RH30	soft_tissue_RH41	lymphocyte_REC1	esophagus_TE8	pancreas_PANC1	kidney_KMRC3	lung_NCIH2291	lymphocyte_L428	unknown_HDMYZ	skin_MCC13	skin_MCC26	prostate_22RV1	kidney_A498	kidney_VMRCRCW	colorectal_SW837	colorectal_LS180	colorectal_SW620	colorectal_COLO320	central_nervous_system_SF295	central_nervous_system_A172	central_nervous_system_GAMG	central_nervous_system_KNS42	blood_JURKAT	blood_PF382	lymphocyte_DEL	blood_SUPT1	central_nervous_system_SW1783	central_nervous_system_42MGBA	central_nervous_system_U87MG	central_nervous_system_U118MG
	KVCQGTSNK	43	59	-3	35					45	39	65	37	55	59			29	49	41	64			69		69	63	51	54	61	61	50	65		61	58	65	39	64		65	36	44	36	43	13		15		59	63	61	31	30	45	-15	31					-13	43			55	40	40	59	8		47					67	23	62	48							56	61									56	64	69	58	47	51	46	68	63	43	61	32					19	38	53	57												60				25							71		43	47	42	65	38	43		67		43										49	63	4		11	60	11	24	41	64	55	44	48	33	55	43	46	60	64	41	64	63	27	65	66	47	52	44	40	72	36	56	42	51	70	64	22	66	61	55	65	65	60	28	72	49	25	54	53	65	55	67	55	42	63	16	58	71	69	37	49	41	66	11	48	55	65	55	60	74	41	9	43	64	71											60	68	61	70	62	66	57	56	9	16	74	63	58	20	61	62	73	65	65	9	33	76	69	60	53	73	64	56	56	68	50	25	63	26	4	54	67	65			50	62								61	66	64	57					51	46	39					33	49	42	65	68	55	62	51					52	13	26	57	68	68	68	27	65	25	73		38	12	46	69	63	59	40	64	44	29	42	56	56	14	66					67	-27	72		48	59	57	71					61			57			50	59	53	67				42	59							53	54	34	56			69	62	58					65	51	59	19					51	50	59	61
	FSNNPALCNVESIQWR	46	63							45	56	63	54	61	46	35		57	57	59	61	59	56	55	59	54	30	44	36	46	47	43	52	64	43	56	52	63	59	55	55	65	58	55	69	49	50	0	70	50	54	58	43	52	62	48	49	55	56	54	54	28	50			50	34	20	55	29	1	43	63	40	41	-4	59		62	62					46		56	66									66	69	73	62	55	67	62	71	67	53	60	50					39	38	51	57	59	30	49	39	49	61	69	58	5	29	51	58				60					57	54	62	28	57	65	56	66	36	61	49	66		58	56	45	60	53	60	47	53	39	50	69	72		36	14	73	31	58	54	58	53	60	61	54	55	47	51	59	60	23	62	58		60	57	35	53	51		47	36	60	63	51	44	60	53	48	31	53	59	64	49	5	60	49	41	63	55	68	55	56	57	49	71	-7	50	62	57	39	63	57	67	70	46	45	34	56	54	73	42		24	46	61											49	59	5	63	48	57	49	64			59	40	35	5	73	70	72	56	62	6	16	71	70	40	41	59	62	47	51	61	42	37	55	6	-5	56	65	67	59	48	26	38	57	56	68					52	57	53	56					58	60	58							46	69	66	53	54	21					62	-9	2	59	70	65	70	20	66	55	71	-23	-4	38	50	70	58	63	53	61	60		44	59	42	41	53					59		59		38	48	61	64					56	52		50			57	59	60	62				44	57	43	49	45		59	58	33	50	23	54	48	49	52	54	48	62	72	-31	-14	71	49	58	6					53	26	54	61
	IICAQQCSGR																																																								34																							36																	6	25	71	36																																																																																																																																																																				30	51	87
	DEATCK									34	36	53	41									44	37	43	47					44	47	41	51		23	56	40	24	54	7	45																				8														4				38	15																	15	37	60	49	27	43	37	56	34	41	36	25									19	38	-37	22	36	31	45	42																			12	41	33	33	12	37								23	40	6	17				35	29	66	41	27	31	39	22																																																		32		43	16					35	61	36	27																		43	14	44	58								44	49	29	45	12	2	57																					23	35	38																																									12	55	-45		42	50																																			43	32													42		41			35	40		51	46
	DTCPPLMLYNPTTYQMDVNPEGK		23																															28	5	40	10					32	4	13	37					58	36	34	48									10	17																	14																	23	40	61	42																																																39																																																		30	23	32	27															16	16	16	21	41	19	47	37																						45	24	18	42	28	40	3	39	-3	22	34					45	41	24	39	25	14	46																																				32	19	30							27																																																													25	37																			42	32													25	-3	-14	-29
	YSFGATCVK		39							52	54	71	31	60	60	16	-7	47	45	47	56	29	47	61	51	54	47	47	45	51	38	35	47	51	51	57	60	49	68	29	53	49	36	50	62	31	62	20	65	41	67	66	19	80	66	49	67	65	65	51	42	25	37												-19		68		43	37																	55	63	81	66	39	55	59	69	65	38	56	36					23	11	50	37	50	39	31	31	42	51	65	55								31							70	31	50	49		27		4	16	44								44	33	22	36	56	68	19	46	48	75	16	42	21	42	36	46	57	41	54	52	16	53	53	34	58	50					56	35	37	72	59	54	59	56	64	51	24	53	50	51	54	57			51	28	26	55	43	52	48	39					27	59	60	54	72	41	65	36																						64	49	53	68	53	64	46	63								58	67	35	50	30	21	73	62	53	41	64	50	39	40	52							56	63	45	33										35	51	60	48					51	51	46							38		63	23	41	25																				62	47	56	34	51		-7	16													17	21	46	63	52	58	34	48								46	53	68				52	56					63				24	53				65	73													49	35	51	48
	NYVVTDHGSCVR																													33	44	46	49	44	22	63	36	42	39	11	23	31	37	21	44					31	53	42																																													28	40	62	36					53	40	45	26																																																																																																																34	-18	47	31
	ACGADSYEMEEDGVR		18																			21	15	43	27	31	29	31	18	29	16	15	32	35	31	20	44	10	46	3	39	38	4	39	38	17		12		10	19	30	20									23	37																	9																	29	32	50	37	10	25	35	45	46	38	40	8									33	-12	8	21	20	30	34	27								18							42	-5	28	19										13	-2	33	25	21	34	3	21	42	57	22	26	41	54	0	23	26	13	15								47																																		32	16	49	34	30	39	43	38	40	27	47	33																						40	27	43	37	29	35	14	24								23	48	16	18	14	12	53					38	26	24	37							43	39	50	25										18	34	35	25					32	32	25							39		41	14	1	17											48	21	45	28	54	23	19																																							37	39										56				40	27				42	33					43	26	18	25
	KCEGPCR																																																																																																16	-5	47	32
	KVCNGIGIGEFK	40	52	53	54					54			56	44	40	28	17	37	49	47	56	40	38	51	45	49	41	44	42	39	43	43	48	44	45	53	51	45	51	28	58	48	43	48	51	48	53	44	57	39	47	44	41	43	47	44	35	46	46	46	46	32	46			57	42	45	46				55	47	38	31	53	36	56	52																	47	37	54	37	49	60	54	54	45	45	45	40					36	18	55	44	50	52	33	28	49	47	47	55								44					40	43	55	39	42	47	37	63	45	43	50	62	35	56	63	37	41	32	46	52	45	25	50	62	68	29	55	11	61	40	49	60	54	53	59	60	57	58	46	41	50	56	61	65	50	30	51	52	52	57	43	52	53		50							51	52	59	60	62	36	57	54	42	65	52	49	51	53	61	51	62	30	51	58	58	50	58	45	67	50					53	68	48	5	38	48	58											67	56	62	52					34	38	62					62	61	34	61	26	31	59	62	39	52	61	62	47	56	59							63	51	46	42	69	68	60	47	63					57	58	67	53					58	52	50							64		59	55	63	34					58	56	24	55	64	60	63	39	53	55	61	46	40	49	55	52	58	59	57																	25	39	35	50											57	54	51	45				67	52					66	62	49	49	50	52	52	49	46	44	47	54	63	28	29	61	55	51	42					58	30	50	52
	NLCYANTINWK	50	40	-3	20					45	45	75	15	69	67	31	10	44	46	54	64	51	57	67	64	53	40	51	51	66	53	48	57	62	56	50	68	64	66	32	60	62	46	46	67	37	59	31	71	71	75	73	56	77	79	61	70	73	66	59	61	25	30														77	31	61	72																	62	63	80	64	54	61	64	76	72	65	73	53					14	51	59	51	70	43	44	34	47	68	75	66															71	13	51	37	23	49	31	45		71								60	53	21	48	58	73	28	44	16	73	29	57	53	57	55	58	60	32	57	63	44	70	65	50	71	65					54	50	35	77									53	68	67	63			65	46	40	59									52	73	72	60	64	36	78	44					55	71	47	23														66	69	62	71	54	59	51	66	32	39	68					65	69	48	60	7	24	75	64	45	48	68	63	54	51	64							74	62	53	44										61	65	63	57					66	55	52							56										61	54	45	65	55	71	66	14	65	56	76	-10	43																							29	49	57	74	55	55	35	47								42	66	78				54	68					70		41	50	29	50	53	54		71	63
	CNLLEGEPR		13																							35	41	22	34		24	28	23	36	27	40	34	13	39	26	39	37	39	20	40	26	40	15	18	-2	34	26	9	37	21	20	29	38	24	21	11	-5	3										61	42	18	33				20																	48	28	52	44					62	45	28	42					13	16	26	30	14	33	0	27	5	31	37	53								26							50	19	28	32	14	42	19	16		23								9	34	10	28	38	57	18					24	29	14	22	18	38	19	37	29	22	31	29	18	42	33	31	40	41	17						7																									12	35	38	33	44	24	44	32									31	55	40											32	26	42	33					9	29	22					32	38	13	35	-5	7	51					40	13	40	38							41	45	47	13										15	31	43	23					35	24	12							23																46	22	44	14	47	17	1																																							44	45										47
CYS 775	EILDEAYVMASVDNPHVCR		22							11			45	8	13	44	9	15	16	16	4	22	1	18	5	19	10	28	17	20	17	23	8	27	15	19	16	-3	16	40	19	25	27	25	17	24	3	34	0	22	8	28	10									25	27												9	20	8	15	11	23					17	14	11	1									18	22	10	7	25	26	12	28	18	45	20	25					37	17	27	17	27	36	40	21	30	19	22	10	-6	21	11	2				3							13	14	17	22	25	16	16	16	41	17	-1	18	13	39	36	37	34	22	18	22	19	8	10	18	12	29	15	13	23	13	14	20	18	19	26	31				9	12	-1	4					19	7	20	-3									11	13	11	8	24	15	16	23	22	19	13	12	10	12	18	20	21	28	20	14	-2	12	13	22	20	21					25	10	31	29														7	2		13												24	19	18	29	26	26	4	20	27	8	13	10	15	12	8	29	22	27	34			8	10	14	16	31	13	35	19	15					17	8	11	25					20	21	18					37	27	21	12	12	15	20	14					4	26	25	-10	14	11	8	19	10	21	-2	47	20	14	7	19	12	13	13	16	4	15	14	14	13	-2	24					16	16	23	29					0	-3	5	1	3			15			1	5	6	16				12	12	14	-3	13		-7	5	12	10	47	1	11	8		1	6	18	9	29	35	-3	-4	13	17					15	10	-4	9
CYS 818	DNIGSQYLLNWCVQIAK																				31	57	38	40	27	35	68	45	60		31	34	35	41	28	47	36		30			39	42	31	43																																																				32								35		29																																41	17	30	25														38	45	28	38																			37	38	45	42																	34	43	47	48	25	28													46	47	47	35	29	46	44	27																																																																																								38																42	19	38							21	42	30	29																									43			50			41	39	41	36										48	43	50													47	36	52	19
CYS 818 *	CVQIAK	50	60	70	69					73	69	63	65					69	58	59	59	60	57	59	77	72	63	62	63	74	71	72	68	67	74	68	69	73	63	59	55	66	70	70	68	68	61	64	75	64	59	53	59	59	61	68	54	67	72		74	69	38	53	57	71	58	67	68	68	64	60								61	57	52	60	65	62	53	66	59																									55	71	69	76	67	74	75	73	70	71	72	70	64	68	66	66											52	65	59	61														59	48	69	60	58	55	36																65	48	63	60	59	70	71	63	63	72			61	67	18	53											67	75	68	66													52	63	66	59									62	55	69															66	64	71	55												64	58	56					64	55	65	61	45	73	70	25	70	68	64	71	53	67	61	70																62	58	55					70	63	60	45	52	66	63	62									59	69																																																			72	54											61	72
CYS 939 *	LPQPPICTIDVYMIMVK		29							36			56	49	42	59	34	26	46	53	45	66	44	44	36	48	43	58	52	39	46	48	45	42	46	59	48	58	45	30	46	47	57	50	50	39	46	36	52	45	42	38	39	36	36	44	27					31	12										63	23	53	31	60	8	52	33	62	51	61	59	49	44	54	53									39	51	51	44	54	65	53	57	43	51	38	53									66	33	61	60	61	42	38	59								32							46	38	31	39	38	38	32	35		41								55	44	36	44	43	52	20					52	30	51	55	62	30	30	55				45	43	43	48					29	61	47	46		39							32	27	45	44	39	50	47	29	7	46	25	34	20	22					49	51	45	38	40	34	55	21									57	24	41																			51	9	38					33	45	32	47	25	33	46					27	32	21	35							43	55	59	22	43	29	43	24	48					21	45	39	42					42	55	35					25	32	65	24	48	40	33	28					53	47	46	46			46	19	46					30	39	22	29	27	11																	24	21	64	26					40			46				31	30	31				42	42					42	31	32	41	24	35	52	43	34	-4	-6					40	33	48	19					45	35	37	40
CYS 950 *	CWMIDADSRPK		47							61	44	55	70	46	51	40	13	32	48	43	46	46	53	44	58	43	45	46	55	54	48	57	51	51	47	65	57	43	47	37	48	46	68	54	51	40	51	28	41	53	49	33	32	48	20	25	35	41	41	28	39	30	39										51	48	32	32	51	36	44	48					44	29	54	48									48	43	47	41	50	49	38	46	47	61	50	62					51	58	61	69	54	39	61	64	61	58	52	65				47				34		28			37	55	44	48	37	40	52	57	41	53	46	56		41	19	54	66	36	33	49	54	41	57	47	55	28	42	50	45	46	51	37	57	53	50	52	52	65	46	41	50	52	49	49	52	30	29	51	44	44	59	43	58	24	40	47	31					55	50	54	54	49	37	47	49	21	44	44	46	30	37	47	42	49	30	63	61	55	41	48	54	60	33					28	55	43	43														52	52	46	39	55	49	68	45	21	50	45	47	39	19	40	49	57	66	56	39	44	50	34	50	50	47	45	48	41	53	46	52	53	38	30	42	57	52	45	63	39	38	37	26	46					41	54	41	52					52	49	50					16	9	49	51	40	46	48	26					62	16	31	58	53	49	55	31	56	57	57	7	31	41	52	44	59	47	41	61	23	20	32	45	43	45	53					59	50	43	-4	35	47	58	52	46	57	66	60	54			55			53	54	44	49				50	49					62	53	67	56	19	44	49	49		40	49	45	52	25	8	52	53	63	35					50	55	64	65
CYS 1049	TPLLSSLSATSNNSTVACIDR		31											30	16	20	23	9	23	21	22	30	29	24	25	40	26	36	25	22	21	21	29	26	29	26	30	45	17	16	18	36	29	22	32	24	25	17	32	41	37	15	30					19	16	15	15	23	16												29				28	33																	42	35	42	44					41	34	35	24					30	41	49	34	43	28	39	31	29	20	34	40								29							49	26	23	31			39		41	46								39	41	17	18	27	48	27	37	14	50	19	41	30	38	40	46	41	38	47				35	33	39	31					37	23											43	47	39	40			32	21	14	32	39	41	25	38					30	24	26	20	42	34	48	29					32	51	38	31														42	41	26	33	41	33	27	45	15	20	39					38	41	24	35	28	38	42					34	35	32	36							44	37	45	39			32	19	47					27	39	30	41					36	34	34							47		34	46	25	24					40	44	23	29	49	35	47	23	36	38	43	15	17			39	31	36	31																	31	24	39	47					28			29				30	41	32				26	33					26	32	16				35	22		39	35													20	7	6	27
CYS 1058	NGLQSCPIK		30															24	28	32	45	32	38	39	44	38	30	34	38	43	36	40	43	43	47	42	52	46	40		26	36	6	29	42	20		32		44	51	42	34					48	54	37	44	20	30												17		55	22	34	50																	42	40	57	49	39	46	38	52	46	31	43	31					6	39	47	34	44	23	22	31	38	39	52	51								28							62	32	47	39	39	53	36	43	37	47								43	48	29	35	45	70	35	32	14	54	35					52	48	44	51				29	45	51	41	39	39	50	54	37	29	42	49	39	41	45	35					45	38	43	47			44	42	35	39													52	33	54																							45	47	49	47								39	45	31	32	38	48	25	35	30	31	50															42	42	50	26																		44	42	33																	45	40	30	39	55	36	49	16	41							33	20	36	15																					24	32	-8	5																							42	9	43				46	56

EGFR	DNA copy number	1.13214108944071	1.37498330624223	1.24572085783884	1.24224395966337	1.68444004061865	1.59963421783799	1.17388484147859	0.874920296105918	0.988816187501611	1.27098399819888	1.01175802712821	1.4538099444745	0.984270692210935	0.975962646098449	1.10746714674445	1.03312271261213	1.1186822667286	1.06785008837962		1.3249833476519	0.646214728123304	1.27395233560188	1.03269886406905	1.08483062560747		1.1363800308231	1.03601767099829	1.18547582196931	1.17039500995853		1.13837406659744		1.13844228403266		1.33741354129278	1.34614009631025	1.03205743806574	1.32399698231109	1.03885965356006	1.30376001373616	0.903342897293527		1.1401442221705	1.34841804456683		1.02807853170218	1.2177298021841														0.916269762161808	1.51844034105499	1.30965622200778	1.2424798166596	1.02799699196884	0.98672563685263	1.06765555525935	1.24515651476054	0.937342648868863	1.06933340507899		1.65803696767012	1.3120164150165	1.08932902973738	0.894771678081665	1.49545802447857	1.21737241972169	1.0243765219868	1.13161970087697							1.19730781517682	1.00588897031684	0.847937394705937	1.00309130483451	1.12781331205935	0.987816384030014	1.01176508396365	0.968431623494522	1.23480101649662	0.98457782180227	1.62613747165809	1.06616910900278	3.67085335550115		1.18306186729702	0.753113357912793	1.04635251113944	1.06860596151054	1.38058953897153	1.10814840456332	1.18320064943176	1.03994204933279	1.0058081446376	1.03812377666003	1.29869014552301	0.984533306127092									1.1954405112586	1.01265855189498	0.823854054388994	1.28392899923897		1.25066108845455		1.4430802324478	1.02921545334302	0.958576317668148	1.18856241217064		1.4265727611964	1.24658850228503	0.995541410905578	1.21288092436168	1.41408106823655	0.812037513999711	1.49547029452661	1.11552599125312	1.16284335703923	0.850486294669871	0.89724951976598	1.15879011203618	1.27007584035348	0.959049699629263	1.28473417292692	0.963539203659212	1.11906264697067	1.16831914940265	1.15543864386256					1.84819651729354	1.26703662968055	0.885191261120428	1.11119736960365	1.47949304338984	1.67509744063324	0.986897048090632	1.09265724268325	1.25399044143443	1.17981971128085	1.29977713329763	0.971277240265016	1.06132125827399	1.29816970603445			1.24382493384887		1.26652266420779				1.12715714464805	1.17447456081733	1.01136138678026	1.08889712070188	0.945486021650816	1.02351151476622	1.37171495406896	1.34246618736259	1.12175148519376	1.30720269562121	1.04257885304567	1.03476964133785	1.08994662031966	1.31308694115295	1.03313549638331	0.93013180803371	0.998881933578161	1.27855663713967	1.37489621108669	1.23910000066975	1.12936199718175	1.02217382661782	1.83206147214113	1.71605046175682	0.88474376485063	1.11553568386958	1.26563492834005	1.57317869475917	1.04123134969887	0.961309145476694	1.0189690896361		1.16963941578844	1.29892637371904	1.11138160172144	1.32075811092868	1.11003228937001	0.970516563480336	1.80482645577723	4.87105628311712	1.92790178298606	1.58877529165723	1.3782889231592	1.76613804184907	2.87242510842576	0.85453269031572	0.60227075543016	1.30363746151768	0.926676534021907	1.01145411137857	1.25605943081763	1.1386098374483	1.03818688184649	0.982141912961883	1.22620504896882	1.28358224183162	1.6902608245943	1.15532678011902	1.04711919478455	1.00591106010385	0.998733556350701	0.600180932348743	0.992863737465231	1.00004850081523	0.940374458147165	1.58738351527405	0.990385253495311	0.754181871658662	1.17638424956771	1.02843735921052	0.922548061680918	1.03624259978459	1.20035033972704	0.949603684256136	0.95665583514226	1.05514991093918	1.21748811996981	1.07018582850024	1.09072145781975	1.02533206872573	1.17394608762845	1.08242697247394	0.989258289333001	1.52539349147004	1.30839362964736	1.03634918361876	1.36225617543244	1.4488261517161	4.72970131952453	1.62661141054242		1.53923598862816	1.19559406383536	1.18684911966372	1.13217915319333	1.06750496540728	1.64657818465225	1.3116401853701	0.980327976254982	1.45517735103448	0.958507872976138	1.42408971438124	1.42762298079611	1.98459325697518	1.16050358808926	2.04818420276846	1.72046154537756	0.931350762405542	0.948541761830692	1.08070842688267	1.20270263932001	1.12478890637203	0.9854545718296	0.993713755462081	0.902548790038864	0.983034936634405	1.00725113136815	1.29797348612159	1.04066081931771	1.2077579935055	1.26917932212179	0.98968662909803	1.11269437201635	0.998562716660001	2.46576579187809	1.33059225816469	0.835794101933556	1.00400002993162	1.20627401599641	1.03329146710786	1.30344115477616	1.12896193974014	0.906175434670948	1.20720745934413	1.05565266363002	1.1762041727514	1.25929530825758	1.31082226363693	1.08986443810086	1.0001770108578	0.902238168981873	1.21593672373524	0.879290752735597	1.83050127456695	0.600863604389119	1.07160528092201	1.13837788670284	1.09125679344545	1.04781294446491	1.22590848582056	1.04875031249068	1.13923817049139	1.21319993219468	1.50668543175063	1.25611291241995	0.94235667801913		1.10973712145262	0.814501020522694	1.097427648038	1.00324263594242	1.06591471364121	1.50038199574831	1.58263144334729	1.34066873031546	1.00680849017273	1.41204336994659	1.02492668761681	1.09366983865764	1.26645573215289	0.996421449268709	1.03396462716444	1.04039413101106	1.01651900251234	1.22128388422674	1.05592667775521	1.38178168628533	1.09167446662884	1.04812895194596	1.04721363784726	1.04574397677306	1.38396919201514	1.44128032714227	1.56420720604353	1.16702228891946	1.45791237983425	1.13617563024623	0.847965838034174	1.02499737978761	1.27572132064029	1.21732682548801	1.03625950921976	1.00386917450942	1.30477699453978	1.47390430939634	1.68936491856674	0.824459400534833	0.82544057795804	0.971918237411496	1.65192487743215	1.42685348729808	1.28581982527492	1.13899467124737	1.08206496546822	0.995570321435116	3.3964595834401	1.32520146577464	1.01439460278888	1.40534924266278	0.962756005728244	0.900489805532847	0.994293331375472	1.17314225746997	1.27600367812976	1.45764157610389	1.28167076250546	1.04150435453633	1.04289018208103	1.41624242964539	0.88693604241673	1.59039560309584	1.64043712721341	1.4926819863469	1.16206493701859	0.997813659166362	0.998995350047962	1.16443776897439	1.14891171897134	1.28338512424257	1.21215553719339	1.04819711892221	1.2831211931026
EGFR	DNA mutation status	0	0	0		1	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0		0	0	0	0		0		1		0	0	0	0	0	0	0		0	0		0	0														0	0	1	0	1	0	0	1	0	0		0	0	0	0	0	0	0	0							1	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0									0	0	0	0		0		0	0	0	0		0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0					0	0	0	0	0	0	1	0	0	0	0	0	0	0			0		0				0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	1	1	0	1	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	1	0	0	0	1	0	0	0	0	0	1	0	0	0	1	1	0	1		0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	2	0	0	0	0	1	0	1	1	0	0	0	0	1	0	0	1	0	0	0	0
EGFR	RNA expression	1.4905701304462	4.34340782229781	0.0565835283663675	0	2.63459326844576	0.0976107966264223	0.189033824390017	0.176322772640463	1.43295940727611	2.20789285164133	4.50842865253186	0.75702324650746	4.16108148227718	4.8703647195834	5.69682846458871	0.367371065648529	1.35049724708413	3.3533232911629		4.16188768237689	5.50493813164961	5.60821785302146	4.3037807481771	5.31324585178756		4.03298241669943	5.96624587322494	5.44824022521607	3.88752527074159		5.61087719947195		5.18269229751619		4.96069703930431	7.41125674622079	5.9902741833186	6.13975597548131	1.4541758931858	5.37851162325373	5.64270157183323		4.66845955691538	6.32750773458721		4.2637856138908	1.58014548442338														0.150559676575381	0.970853654340484	0.124328135002202	0.16349873228288	0.495695162624069	0.344828496997441	2.58255600301406	1.55090066464752	0.124328135002202	0.070389327891398		4.99909803370561	2.90303827011291	1.96716860753263	0.263034405833794	4.44028782084042	0.0840642647884745	3.67919857056692	5.72683121703249							4.39780296186249	5.07809742302666	0.137503523749935	0.176322772640463	0.070389327891398	0.150559676575381	0.286881147788161	0.070389327891398	0.263034405833794	0.238786859587116	5.93522399406003	4.10349763970334	9.25802418543952		4.8972404255748	3.33913738491959	3.64385618977473	5.55887985347544	4.81352468929781	5.55397480823747	5.89602960297675	5.86690797814317	0.124328135002202	0.150559676575381	0.20163386116965	0.150559676575381									4.58496250072116	4.61470984411521	4.34127418369217	5.97269265400426		0.238786859587116		2.93734439215023	2.10097764772482	0.16349873228288	1		0.137503523749935	0.0976107966264223	0.070389327891398	0.333423733725192	3.45811948117451	4.31976242766925	6.50827017556779	5.34589308568741	4.99367436175059	4.35825558670513	5.17032569441556	5.9706236144706	3.47767732756531	4.32984117653063	4.98732086592925	5.30669970727279	0.0976107966264223	5.52136487844622	4.71808758396052					7.06856333533888	5.50112063427539	3.611172380044	5.62410089462811	5.46139758992616	6.24792751344359	2.74631276642546	5.9469647411558	5.47378691161437	5.94649694120329	5.10810622368613	6.10307794659757	4.62819033461521	5.01256867350306			5.18388345903223		5.65477921695952				4.26453643099903	4.16430358309365	6.39574832817903	5.33842441478356	2.13093086982645	1.33342373372519	5.54751152364422	3.89627184880738	3.02856915219677	4.58676474335514	1.49569516262407	6.28188367456292	4.57893871309339	5.39437694495706	4.85598969730848	3.4867143730307	3.92409988564074	3.74631276642546	3.48928602262588	3.44493204894218	5.99909803370561	4.93734439215023	8.08719761557795	7.69146437341683	4.98823022306046	4.49121175600309	4.41683974191283	5.07937811111865	5.39780296186249	6.15987133677839	4.45022149589718		2.17312743348066	4.82883464946806	5.47021145739054	3.80322703643493	5.42021289061078	3.09929520433778	6.56757586852411	9.67364475243824	6.30268461411838	5.32373033752135	6.80309784950483	6.13996056954546	8.35952995532291	4.30669970727279	3.48026512205446	2.16349873228288	3.08746284125034	4.06695024392463	2.63226821549951	5.70182625841205	3.72574115650395	5.09043004232162	1.50589092972996	3.59454854955035	5.79181407116183	0.137503523749935	0.124328135002202	0.189033824390017	0.137503523749935	0.150559676575381	0.137503523749935	0.124328135002202	0.137503523749935	1.83995958748953	0.799087306074004	5.62585493136806	7.04494049127973	5.35614381022528	4.78764141448333	5.6564963705535	4.85449441815488	5.9143253300853	5.10475598696226	0.150559676575381	0.214124805352847	5.35085080548338	5.50652577904312	5.17472598770613	0.0565835283663675	5.15340002773506	5.9979697822671	6.58345891013077	5.18269229751619	5.59006301881225	3.55704241526372	6.31795521831244	9.18256816161399	3.94579495674006		4.42223300068305	5.33556900555675	5.36946648365072	5.21529030565123	3.93734439215023	5.88386515450979	5.66931028620247	3.80426011563474	5.48446041312882	1.83187724119167	0.632268215499513	0.545968369105293	7.20084957463721	5.07081863753328	5.30997649237056	6.20554891117303	2.07724299893246	4.86393845042397	4.43028527297778	3.88264304936184	5.39231742277876	0.0840642647884745	0.111031312388744	0.214124805352847	0.137503523749935	4.11270013274936	5.48574882137778	5.4757334309664	5.9797967182782	0.422233000683048	0.124328135002202	0.150559676575381	0.124328135002202	7.6442889333787	5.32373033752135	4.63343121035563	0.16349873228288	0.070389327891398	0	0.37851162325373	4.90785207184596	1.14404636961671	5.12969515665378	4.70321146739115	5.77214959078454	4.603477988254	4.47638168756724	2.72465027173297	0.176322772640463	0.31034012061215	0.263034405833794	0.111031312388744	5.29975751183932	0.495695162624069	0.286881147788161	5.32840565895857	3.72246602447109	4.78711898281334	6.97911075501579	5.27500704749987	7.43162295971329	4.84096670448742	6.07831095000713	6.47654370621426	3.97636363573276		0.111031312388744	5.5963388642052	5.37989816352469	1.22650852980868	0.704871964456353	4.74038793246835	4.63923216324928	5.74416109557041	6.14139191617073	5.54565954002547	2.72900887033786	3.1811025507538	2.85798099512757	0.298658315564515	0.622930350920177	0.0840642647884745	0.176322772640463	5.10433665981474	0.111031312388744	2.49825086752783	0.0976107966264223	0.150559676575381	3.80219321694182	5.10726939359254	4.26077843189343	6.55366768848306	7.47986108501682	5.17592374206376	7.69285956238577	5.69181329717138	3.82883464946806	0.124328135002202	5.25323293853803	0.150559676575381	0.124328135002202	4.29572302453997	4.77873424411784	5.13873256972024	6.34216358328935	0.0976107966264223	0.0976107966264223	0.124328135002202	5.53760669149529	5.4541758931858	4.66505161428921	3.03738222200308	0.20163386116965	2.28688114778816	7.88758619407687	5.85024935828633	6.92041240816079	6.10349763970334	0.0976107966264223	4.35543919724869	4.28466218548316	3.93922657772821	2.8073549220576	5.44028782084042	6.3743439890385	4.16188768237689	3.89917563048051	0.0976107966264223	0.176322772640463	4.88215391728701	5.04745114041639	6.68355610749568	3.62527048937469	0.0976107966264223	0.22650852980868	0.20163386116965	0.286881147788161	4.98686597232911	4.85648777949568	5.10894256866079	5.57288966842058
EGFR	CRISPR gene dependency	0.04	0.18	0.03				0.02	0.03		0.06		0.03	0.07	0.75	0.02	0.02	0.08	0.31			0.05	0.33	0.02	1.00		0.08	0.84	0.79			1.00		0.97		0.06	0.99		0.62	0.03	0.08	0.87		0.03	0.07		0.66	0.17														0.09	0.00	0.10	0.08		0.01	0.03		0.10	0.18		0.04		0.30	0.14		0.04	0.04	0.03							0.09			0.07	0.09	0.02	0.04	0.05	0.05		0.06	0.71	0.31		0.75	0.42	0.15	0.57	0.26	0.97	0.16	0.14	0.09	0.01	0.02	0.03									0.34	0.04	0.05	0.97					0.22	0.04	0.14			0.01	0.08	0.05	0.00		0.10	0.19	0.03	0.19	0.15	0.03	0.02	0.96	0.33	0.31	0.02	0.03	0.08					0.65	0.98		0.09	0.02	0.26	0.04	0.02	0.02	0.09	0.99	0.95	0.81	0.80			0.60		0.94				0.20	0.84	0.52	0.19	0.02	0.03	0.05	0.10	0.09		0.01	0.58	0.21	0.11	0.07	0.07	0.02	0.51	0.90	0.57	0.81	0.84	0.81	0.79		0.11	0.26	0.06	0.83	0.31	0.03		0.07	0.10	1.00	0.02	0.03	0.11	0.99	0.06	0.87	1.00	0.24	0.48	0.85	0.13	0.01	0.11	0.08	0.06	0.03	0.78	0.08	0.22	0.06	0.03	0.75			0.03	0.01		0.04	0.04	0.03	0.04	0.01	0.07	0.97	0.16	0.03	0.03	0.12	0.04	0.01	0.01	0.07	0.05	0.02	0.03	0.03	0.12	0.06	0.02	0.16	0.05	0.04	0.17	0.06	0.05		0.29	0.06	0.28	0.02	0.50	0.10	0.04	0.05		0.02	0.05		0.25	0.19	0.03	0.22	0.27	0.13	0.94	0.06	0.54	0.02		0.09	0.01	0.03	0.44	0.90	0.88	0.01	0.11		0.02	0.95	0.52	0.71		0.17	0.04		0.01	0.02	0.67	0.05	0.53	0.24	0.86	0.17	0.06	0.08		0.01	0.05	0.03	0.10	0.02	0.02	0.57	0.15	0.91	0.40	0.24	0.07	0.14	0.41		0.11	0.22	0.03			0.13	0.02	0.11	0.06	0.03	0.01	0.06	0.05			0.03	0.06			0.03	0.18	0.03	0.11	0.44	0.88	0.06	0.89	0.61	0.99	0.17	0.10	0.20		0.02	0.09	0.06	0.05	0.01	0.02	0.03	0.03	0.06	0.10	1.00	0.02	0.23			0.94	0.07	0.25	0.15	0.15	0.05	0.04	0.02	0.02		0.02	0.51	0.54	0.02	0.03	0.05	0.07	0.07	0.03	0.03	0.07	0.03	0.05		0.03	0.06	0.03

Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
EGFR	P00533	7syd	2.4	13.3	19.0	11.0	30.0	0.1	-1.9	-3.5	-0.2	-0.4	-0.9	27.5	-124.1	-135.1	160.8	E	0.0	0.0	0.1	0.1	0.1	0.6	0.0
EGFR	P00533	7syd	1.9	19.9	11.0	25.0	36.0	0.1	-1.0	-0.3	-0.2	-0.1	-0.9	45.2	40.8	-143.3	164.8	N/A	0.3	0.0	0.3	0.0	0.0	0.5	0.0
EGFR	P00533	7syd	2.0	27.5	18.0	5.0	23.0	0.1	-0.3	-0.1	-0.2	-0.1	-0.4	73.1	-95.1	-105.3	168.2	S	0.2	0.0	0.0	0.2	0.2	0.4	0.0
EGFR	P00533	7syd	2.3	8.4	17.0	14.0	31.0	0.0	-1.5	-0.2	-0.3	-0.2	-0.8	39.3	-173.8	-89.3	115.9	N/A	0.2	0.2	0.4	0.2	0.0	0.0	0.0
EGFR	P00533	7syd	2.0	17.6	25.0	12.0	37.0	0.1	-0.3	-0.1	-0.1	-0.1	-0.3	55.1	-90.4	-66.7	147.0	P	0.0	0.0	0.3	0.3	0.3	0.0	0.0
EGFR	P00533	7syd	2.7	12.9	19.0	14.0	33.0	0.1	-1.5	-0.3	-0.3	-0.2	-0.9	33.6	-173.7	-100.1	120.4	E	0.2	0.0	0.5	0.2	0.0	0.2	0.0
EGFR	P00533	7syd	5.1	0.0	20.0	20.0	40.0	0.1	-3.0	-0.4	-0.4	-0.2	-0.7	40.3	178.3	-78.7	109.5	E	0.0	0.0	0.3	0.2	0.0	0.2	0.3
EGFR	P00533	7syd	1.8	38.2	19.0	13.0	32.0	0.2	-0.2	-0.1	-0.2	-0.1	-0.2	43.2	-60.1	-79.6	171.8	N/A	0.0	0.0	0.3	0.0	0.3	0.3	0.0
EGFR	P00533	7syd	1.9	35.1	11.0	6.0	17.0	0.2	-2.8	-0.7	-0.1	-0.1	-0.4	20.3	-141.7	-69.0	145.7	P	0.1	0.3	0.1	0.1	0.1	0.0	0.1
EGFR	P00533	7syd	2.3	15.0	22.0	13.0	35.0	0.1	-1.4	-2.5	-0.5	-0.1	-0.5	16.6	-110.7	-86.4	145.7	E	0.0	0.0	0.5	0.2	0.0	0.3	0.0
EGFR	P00533	7syd	2.4	6.2	15.0	27.0	42.0	0.0	-1.7	-0.4	-0.4	-0.1	-0.4	60.2	39.3	-94.7	176.7	N/A	0.3	0.0	0.0	0.0	0.0	0.3	0.3
EGFR	P00533	7syd	2.4	5.5	16.0	13.0	29.0	0.0	-0.3	-0.9	-0.1	-0.1	-0.2	54.6	-111.1	-93.2	52.9	N/A	0.2	0.2	0.2	0.2	0.0	0.2	0.0