DrugMap: GAPDH (KB05)

name	peptide	lung_MGH0061	lung_NCIH3122	lung_MGH0651	lung_MGH0261	lung_MGH0732	lung_MGH0653	lung_MGH9153	lung_MGH0752	lung_MGH97967	lung_MGH9521R	lung_MGH92431	lung_MGH91621	lung_MGH8022	lung_MGH8021	lung_MGH8091	lung_MGH9201	lung_MGH1701	lung_MGH100151	lung_MGH1542	lung_MGH100164	lung_MGH90921	lung_ABC1	lung_A549	lung_HCC15	lung_CALU6	lung_MGH1543	lung_MGH1541	lung_MGH8222	lung_MGH1904	lung_NCIH1703	lung_LU65	lung_NCIH1155	lung_NCIH2172	lung_HCC44	lung_CORL23	lung_NCIH1299	lung_NCIH1666	lung_NCIH23	lung_SW1573	lung_NCIH1944	lung_PC14	lung_HCC827	lung_LUDLU1	lung_NCIH1975	lung_NCIH2170	lung_NCIH2122	lung_NCIH1792	lung_NCIH1048	lung_SW1271	lung_NCIH446	lung_NCIH2286	lung_NCIH1793	lung_NCIH1650	lung_CALU1	lung_NCIH358	lung_NCIH2052	lung_MSTO211H	lung_CORL88	lung_SBC5	lung_NCIH196	lung_NCIH146	lung_SHP77	lung_NCIH82	lung_NCIH2291
CYS 152	IISNASCTTNCLAPLAK	42	9	-8	24	-7	4	26	0	6	-4	19	-9	25	43	58	29	9	83	-23	11	63	19	-2	25	17	39	41	57	50	30	35	41	62	37	53	42	23	37	34	25	25	44	40	54	41	5	5	-1	5	11	30	33	29	27	29					17	27	23	23
	LTGMAFRVPTANVSVVDLTCR	50	14	-16	53	-33	6	13	9	-17	-15	5	-25	30	21	40	12	31	16	14	8	61	-28	10	-16	64	36	57	29	38	16	5	-5	14	2	3	4	11	0	6	14	-6	10	2	9	7	-12	2	-9	-13	17	-9	18	-1	29	10	-11	-1	-15	16	12	12	17	50	-16

GAPDH	DNA copy number																						0.972819466627536	1.09311458640248	1.12491344002775	1.34955515777902					1.60454435164745	0.967866526135303	0.954885713930371	0.763527404326902	1.01712545224029	0.994216638611676	1.49495793999641	0.770619679156461	1.70251037698124	1.11071889053385	1.27291746969659	1.43077887070461	1.31908266800708	1.09130614442593	0.84560565292513	1.34115109735223	0.917483723981567	0.990014299320048	1.03179890044615	1.27251714939602	1.20287117761366	1.07852202065843	0.72304662525226	1.02528628617561	1.38378414833904	0.741021514487622	1.1335962676641	1.10634268947422	1.62937070333799	1.06063810837802	0.555960475795651	1.62856545341802	0.601930231934117	1.11642279445943	1.22503623582686
GAPDH	DNA mutation status																						0	0	0	0					0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GAPDH	RNA expression																						11.9938936813662	12.4723608395839	12.604553229079	12.5809415892691					12.9844184588011	12.2228552654145	12.080584386304	11.4363992366828	11.3209697369718	11.3877481007113	12.7796783222777	11.7211419219321	12.8438621805949	11.8929601588416	12.4653623316722	12.6745453938459	13.0826813029504	12.4117228219514	11.8586027124571	13.0911378245811	12.2649703189574	12.3156590584404	12.2544381482673	13.093962186249	11.5884804128298	12.5140482688532	11.5100223588138	12.8542840201762	13.0599527793871	11.6697266062302	12.3255022239247	12.3729738565412	12.3278613590147	10.9720463978469	10.9500455053465	12.5428384165361	10.8129794712515	11.185742682247	12.4075598857255
GAPDH	CRISPR gene dependency																						0.88	0.93	0.92	1.00					1.00	0.98	1.00	0.93	1.00	1.00	1.00	1.00	1.00	0.82	0.91	0.98	1.00	0.97	0.98	0.93	0.99	1.00	1.00	0.98	0.92	0.98	1.00	0.99	1.00	0.93	0.88	1.00					0.97	1.00	1.00

Cysteine	Gene	Uniprot Accession	pdb	Depth (Å)	Absolute SASA (Å^2)	Half-Sphere Exposure (up)	Half-Sphere Exposure (down)	Coordination Number	Relative SASA	Estimated h_nho1 energy (DSSP)	Estimated h_ohn1 energy (DSSP)	Estimated h_nho2 energy (DSSP)	Estimated h_ohn2 energy (DSSP)	TCO (DSSP)	Kappa (DSSP)	Alpha (DSSP)	Phi (DSSP)	Psi (DSSP)	Structural Motif (DSSP)	Pocket Volume (Å^3)	Presence at Interface	Local Basic Content (Fraction of Local Neighbors)	Local Acidic Content (Fraction of Local Neighbors)	Local Polar Content (Fraction of Local Neighbors)	Local Cysteine Content (Fraction of Local Neighbors)	Local Structural Content (Fraction of Local Neighbors)	Local Aliphatic Content (Fraction of Local Neighbors)	Local Aromatic Content (Fraction of Local Neighbors)
	GAPDH	P04406	6ynd	7.2	0.0	25.0	24.0	49.0	0.0	-2.5	-2.2	-0.6	-0.5	-0.9	37.5	-135.7	-134.8	154.6	E	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.7	0.0